Cytogenetic toxicity and no-effect limit dose of pesticides

Integrative analysis in toxicological assessment of the insecticide Malathion in Allium cepa L. system

“…Asita and Makhalemele (2009): Commercial compounds of Malathion at 0.034, 0.069, 0.137% solution (corresponding to 0.34; 0.69; 1.37mg mL -1 ); 7. Kumar et al (1995): MT ranging from 0 to 100 mg L -1 ; 8. Kumar and Sinha (1989): concentrations of 0.1;0.5;1.0;5.0;10.0; 25.0; 100.0; 250.0; 500.0 ppm (corresponding to 0.0001mg mL -1 to 0.5 mg mL -1 ).…”

Integrative analysis in toxicological assessment of the insecticide Malathion in Allium cepa L. system

“…Asita and Makhalemele (2009): Commercial compounds of Malathion at 0.034, 0.069, 0.137% solution (corresponding to 0.34; 0.69; 1.37mg mL -1 ); 7. Kumar et al (1995): MT ranging from 0 to 100 mg L -1 ; 8. Kumar and Sinha (1989): concentrations of 0.1;0.5;1.0;5.0;10.0; 25.0; 100.0; 250.0; 500.0 ppm (corresponding to 0.0001mg mL -1 to 0.5 mg mL -1 ).…”

Genetic monitoring of malathion-exposed agricultural workers

“…As reviewed in Flessel et al [1993] and confirmed by subsequent studies [Balaji and Sasikala, 1993;Amer et al, 1996;Kumar et al, 1995], technical grade and purified malathion appeared to induce chromosomal aberrations and sister chromatid exchanges in human and animal cell culture. In vivo animal studies have shown that exposure to technical-grade malathion can induce chromosomal aberrations in bone marrow cells, whereas exposure to purified malathion did not.…”

Biological detection and analysis of toxicity of organophosphate- and azadirachtin-based insecticides in Lathyrus sativus L.

“…Many investigators have observed that the use of chemical pesticides in agriculture causes deleterious effects on hereditary materials in both mitotic and meiotic cell division and causes genetic damage to man, domestic animals, and economical plants (Kumar et al 1995;Natarajan 1996;Ghareeb 1998). Genotoxic pesticides are potentially able to increase mutations in DNA, controlling the expression of various qualitative and quantitative traits that could cause genetic instabilities of natural plant populations and in crop varieties (Crosby 1982).…”

Integrative analysis in toxicological assessment of the insecticide Malathion in Allium cepa L. system

“…Asita and Makhalemele (2009): Commercial compounds of Malathion at 0.034, 0.069, 0.137% solution (corresponding to 0.34; 0.69; 1.37mg mL -1 ); 7. Kumar et al (1995): MT ranging from 0 to 100 mg L -1 ; 8. Kumar and Sinha (1989): concentrations of 0.1;0.5;1.0;5.0;10.0; 25.0; 100.0; 250.0; 500.0 ppm (corresponding to 0.0001mg mL -1 to 0.5 mg mL -1 ).…”

Genetic monitoring of malathion-exposed agricultural workers

“…As reviewed in Flessel et al [1993] and confirmed by subsequent studies [Balaji and Sasikala, 1993;Amer et al, 1996;Kumar et al, 1995], technical grade and purified malathion appeared to induce chromosomal aberrations and sister chromatid exchanges in human and animal cell culture. In vivo animal studies have shown that exposure to technical-grade malathion can induce chromosomal aberrations in bone marrow cells, whereas exposure to purified malathion did not.…”

Biological detection and analysis of toxicity of organophosphate- and azadirachtin-based insecticides in Lathyrus sativus L.

“…Many investigators have observed that the use of chemical pesticides in agriculture causes deleterious effects on hereditary materials in both mitotic and meiotic cell division and causes genetic damage to man, domestic animals, and economical plants (Kumar et al 1995;Natarajan 1996;Ghareeb 1998). Genotoxic pesticides are potentially able to increase mutations in DNA, controlling the expression of various qualitative and quantitative traits that could cause genetic instabilities of natural plant populations and in crop varieties (Crosby 1982).…”

Integrative analysis in toxicological assessment of the insecticide Malathion in Allium cepa L. system

“…Asita and Makhalemele (2009): Commercial compounds of Malathion at 0.034, 0.069, 0.137% solution (corresponding to 0.34; 0.69; 1.37mg mL -1 ); 7. Kumar et al (1995): MT ranging from 0 to 100 mg L -1 ; 8. Kumar and Sinha (1989): concentrations of 0.1;0.5;1.0;5.0;10.0; 25.0; 100.0; 250.0; 500.0 ppm (corresponding to 0.0001mg mL -1 to 0.5 mg mL -1 ).…”

Genetic monitoring of malathion-exposed agricultural workers

“…As reviewed in Flessel et al [1993] and confirmed by subsequent studies [Balaji and Sasikala, 1993;Amer et al, 1996;Kumar et al, 1995], technical grade and purified malathion appeared to induce chromosomal aberrations and sister chromatid exchanges in human and animal cell culture. In vivo animal studies have shown that exposure to technical-grade malathion can induce chromosomal aberrations in bone marrow cells, whereas exposure to purified malathion did not.…”

Biological detection and analysis of toxicity of organophosphate- and azadirachtin-based insecticides in Lathyrus sativus L.

“…Many investigators have observed that the use of chemical pesticides in agriculture causes deleterious effects on hereditary materials in both mitotic and meiotic cell division and causes genetic damage to man, domestic animals, and economical plants (Kumar et al 1995;Natarajan 1996;Ghareeb 1998). Genotoxic pesticides are potentially able to increase mutations in DNA, controlling the expression of various qualitative and quantitative traits that could cause genetic instabilities of natural plant populations and in crop varieties (Crosby 1982).…”