Abstract:Objective: to establish the level of chromosomal instability in peripheral blood lymphocytes (PBL) from healthy individuals and cells from patients with B-cell chronic lymphocytic leukemia (CLL) under co-cultivation conditions and to determine the possibility of inducing manifestations of the universal phenomenon of bystander response in them. Materials and methods. Cytogenetic analysis of uniformly stained chromosomes from human PBL, which differed by cytogenetic markers of sex; the presence of oncological tr… Show more
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