Cytogenetic Profiling in Paediatric Acute Leukaemia; a Report on 746 Newly Diagnosed Paediatric Cases Analyzing the Spectrum of Recurring Chromosomal Rearrangements in B Cell Lymphoblastic and Acute Myeloid Leukaemia
Abstract:Background: Cytogenetics is evolving and different molecular mechanisms we know now have proved to be of diagnostic and prognostic significance in both acute lymphoid (ALL) and myeloid leukaemia (AML). This study aims to find out and compare the occurrence of different cytogenetics in paediatric acute leukaemia. Methods: This is a cross-sectional study of diagnosed B-ALL and AML patients presenting at The Indus Hospital. We studied FISH and karyotype in B-ALL and FISH in AML patients. FISH analysis shows a tot… Show more
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