Cysts of sellar and pharyngeal hypophyses

McGrath, P

doi:10.3109/00313027109071331

Cited by 61 publications

(18 citation statements)

References 5 publications

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“…RATHKE'S cleft cysts (RCC), found in 2-33% of routine autopsy series [1,2], are considered to arise in the remnants of Rathke's pouch, an invagination of the stomodeum [3,4]. They are classically described as benign epithelial cysts containing mucoid material.…”

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confidence: 99%

Symptomatic Rathke's Cleft Cyst Coexisting with Central Diabetes Insipidus and Hypophysitis: Case Report.

et al. 1999

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Symptomatic Rathke's Cleft Cyst Coexisting with Central Diabetes Insipidus and Hypophysitis: Case Report.

et al. 1999

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“…Turcu et al (8) reported that 1.3% of pituitary stalk lesions were caused by RCC. RCC has been indicated in 13-22% of normal autopsies (9)(10)(11)(12), and it has become more common as an incidental cyst due to the widespread use of MRI (13). RCC may become enlarged because of either inflammation or hemorrhagic change (4,14), but pituitary dysfunction does not always relate to the size of RCC (5,15).…”

Section: Discussionmentioning

confidence: 99%

Hypothalamic Type of Hypopituitarism and Central Diabetes Insipidus Probably Linked to Rathke's Cleft Cyst

et al. 2015

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A 73-year-old woman was admitted due to weight loss and generalized malaise. The basal levels of all the anterior pituitary hormones, except for prolactin, were reduced. However, they were all elevated in response to exogenous hypothalamic hormones. After starting hydrocortisone replacement, the patient had polyuria of >5,000 mL/day. T1-weighted MRI depicted a low signal of an oval mass in the sella turcica and an isointense signal of another mass at the pituitary stalk. These findings indicate a hypothalamic type of hypopituitarism and masked central diabetes insipidus which possibly derived from the atypical occupation of Rathke's cleft cyst at the pituitary stalk.

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“…Endocrinological data at the postoperative examinations a mixed form of Rathke's cleft cyst and craniopharyngioma that is rare and neoplastic in its behavior. Small, asymptomatic Rathke's cleft cysts are relatively common, found in 13 to 33% of cases at autopsy [6]. The clinical symptoms of Rathke's cleft cysts are usually the result of a local mass effect [5].…”

Section: Discussionmentioning

confidence: 99%

A Boy with Rathke's Cleft Cyst

Okada¹,

Hashimoto²,

Koga³

et al. 1993

Clin Pediatr Endocrinol

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Abstract. We report a 13-year-old boy with Rathke's cleft cyst who had diabetes insipidus (DI), visual disturbance, and GH deficiency. He was admitted to our hospital in 1988 because of polyuria and visual disturbance. He had homonymous hemianopsia and DI; however, the brain computed tomography (CT) was normal. He received 1-deamino-8-D-arginine vasopressin (DDAVP) therapy. In 1989, he was found to have GH deficiency and GH treatment was started. In 1991, a 1.2 cm sized mass was found in the sella area by magnetic resonance imaging (MRI) and removed by microscopic transsphenoidal surgery. Histological examination revealed a Rathke's cleft cyst with craniopharyngioma.In spite of visual disturbance at the first visit, no mass had been found in the brain by CT or MRI during the first two years of GH treatment. However, the mixed form of Rathke's cleft cyst and craniopharyngioma had grown rapidly and was subsequently detected by MRI. He has to be followed up very carefully by MRI for a long period.

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Cysts of sellar and pharyngeal hypophyses

Cited by 61 publications

References 5 publications

Symptomatic Rathke's Cleft Cyst Coexisting with Central Diabetes Insipidus and Hypophysitis: Case Report.

Symptomatic Rathke's Cleft Cyst Coexisting with Central Diabetes Insipidus and Hypophysitis: Case Report.

Hypothalamic Type of Hypopituitarism and Central Diabetes Insipidus Probably Linked to Rathke's Cleft Cyst

A Boy with Rathke's Cleft Cyst

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