Cystic Renal Cell Carcinomas in Adults. Is Preoperative Recognition of Multilocular Cystic Renal Cell Carcinoma Possible?

Aubert, Sébastien; Zini, Luca; Delomez, J.; Biserte, J; Lemaître, L.; Leroy, Xavier

doi:10.1097/01.ju.0000181210.72528.ab

Cited by 45 publications

(31 citation statements)

References 20 publications

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“…Since these early theories, it is apparent that there are several permutations on the renal cysts and RCC theme that merit separation (33)(34)(35)(36)(37)(38)(39)(40). These are noted in Table 3 with comments on their significance.…”

Section: Resultsmentioning

confidence: 99%

Renal Cystic Diseases and Renal Neoplasms

Bonsib¹

2009

Clinical Journal of the American Society of Nephrology

105

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The past two decades have witnessed recognition of several new types of renal cell carcinoma, each with distinct cytogenetic abnormalities. Included are several genetic and acquired cystic kidney diseases associated with development of renal cell carcinoma, the topic of this review. The risk in patients with autosomal dominant polycystic kidney disease is not accurately known but may be slightly increased. The risk for patients with von Hippel-Lindau disease is substantial, and death from renal cancer is common. For patients with tuberous sclerosis complex, the challenge is recognition of the occasional malignancy arising in a field of many benign tumors. Patients with end-stage kidney disease and acquired cystic kidney disease may develop a variety of renal cell carcinoma types. Progress in understanding the molecular basis of renal cyst formation and neoplastic disease has fostered development of targeted therapies that now hold promise for a group of neoplasms whose cure was traditionally dependent on surgical approaches.

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Section: Resultsmentioning

confidence: 99%

Renal Cystic Diseases and Renal Neoplasms

Bonsib¹

2009

Clinical Journal of the American Society of Nephrology

105

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“…mcRCCs have consistently fared better than their counterparts on both cancer-specific and overall survival. 24,[66][67][68][69][70][71][72][73] One potential explanation for this better prognosis is that the majority of mcRCCs tumour volume is fluid and thus, the actual tumour burden is much lower when compared to similar sized solid tumours. 67 As the outcomes of these tumours do not seem to be influenced by the overall lesion size, some experts have even suggested to abandon the current pathological T staging for mcRCC and to reassigned them a new stage called pT1c (c for cystic).…”

Section: Bosniak Category IVmentioning

confidence: 99%

CUA guideline on the management of cystic renal lesions

Richard¹,

Violette²,

Jewett³

et al. 2017

CUAJ

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“…MCRCC must be differentiated from clear-cell RCC with cystic change, which has a worse prognosis [25]. On imaging, MCRCC is a multilocular cystic mass with regular thin cyst walls and regular septa and importantly, lacks an expansile nodule.…”

Section: Cystic Rccmentioning

confidence: 99%

The expanding role of imaging in the management of renal cell carcinoma

Murphy¹,

Jhaveri

2011

Expert Review of Anticancer Therapy

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The management of renal cell carcinoma (RCC) is evolving owing to the increasing detection of small renal masses, greater understanding of the metabolic pathways involved, new targeted medical treatments for metastatic RCC, and evolving surgical and minimally invasive image-guided treatment techniques. Consequently, the role of imaging and radiology has expanded, with new challenges encompassing all aspects of management, including diagnosis, predicting cell type, staging, preoperative vascular mapping, image-guided treatment and biopsy, detection of recurrence and the use of imaging as a biomarker to assess response to treatment. This article is a comprehensive review of RCC, outlining the etiology of the disease, RCC histological subtypes and their imaging characteristics, imaging modality techniques for evaluation of RCC, treatment strategies and the management of small renal masses.

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Cystic Renal Cell Carcinomas in Adults. Is Preoperative Recognition of Multilocular Cystic Renal Cell Carcinoma Possible?

Abstract: Preoperative recognition of MCRCC is possible using strict computerized tomography and/or magnetic resonance imaging criteria. The current study confirms the low malignant potential of MCRCC. Nephron sparing surgery should be proposed when MCRCC is suspected.

Cited by 45 publications

References 20 publications

Renal Cystic Diseases and Renal Neoplasms

Renal Cystic Diseases and Renal Neoplasms

CUA guideline on the management of cystic renal lesions

The expanding role of imaging in the management of renal cell carcinoma

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