“…It stands at one end of a spectrum of renal cystic diseases of the childhood that includes MLCN, cystic partially differentiated nephroblastoma, multilocular cysts with nodules of Wilms tumor, and Wilms tumors. 1 In adults (as in our case), the order would be as follows: benign multilocular cyst, multilocular cystic renal cell carcinoma (MCRCC), and a cystic renal Several authors have reported on the difficulty of differentiating between MLCN and MLCC, whereas Omar et al 6 reported the only case of cystic renal cell carcinoma arising from MLCN existing in the literature up-to-date. Although the arousal of cystic renal cell carcinoma from MLCN is a controversial issue, there is evidence supporting a dynamic relation between those 2 conditions.…”