Cystic lesions of the brain. A classification based on pathogenesis, with consideration of histological and radiological features

Go, K.G.; Hew, J. M.; Kamman, R. L.; Molenaar, W. M.; Pruim, Jan; Blaauw, Eh

doi:10.1016/0720-048x(93)90038-o

Cited by 52 publications

(31 citation statements)

References 56 publications

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“…Although cysts of other sorts can form in left temporo-frontal area, the cysts found in these patients were classified as arachnoid cysts according to the criteria of Go et al, (1993). Importantly, they were not leptomeningeal cysts (Taveras & Ransohoff, 1953), which, given the CSF-like contents, position, and trauma undergone by Cases 1 and 2, is the most likely alternative.…”

Section: Subjectsmentioning

confidence: 94%

“…Arachnoid cysts are abnormal intracranial cavities filled with a fluid resembling cerebrospinal fluid (CSF) which apparently arise as developmental anomalies of the meninges (Starkman et al, 1958;Go et al, 1993;Go, 1995); they have the structure of arachnoid villi or granulations, but have apparently developed with no connection to venous drainage, so that they fill with fluid.…”

Section: Introductionmentioning

confidence: 99%

“…The weight of the brain at autopsy and measurements of cross-sectional surfaces on CT scans indicate that brain volume remains grossly normal but that skull volume is enlarged (Shaw, 1979;Van der Meché & Braakman, 1983;Marinov, Undjian, & Wetzka, 1989). After surgical treatment the cyst occasionally disappears, but more often the cavity persists because of the discrepancy between brain and skull volumes (Go et al, 1993). Arachnoid cysts can be discriminated from other types of cysts that have noncongenital origins, such as injury or disease, due to their contents and structure (Go et al, 1993).…”

Section: Introductionmentioning

confidence: 99%

“…After surgical treatment the cyst occasionally disappears, but more often the cavity persists because of the discrepancy between brain and skull volumes (Go et al, 1993). Arachnoid cysts can be discriminated from other types of cysts that have noncongenital origins, such as injury or disease, due to their contents and structure (Go et al, 1993).…”

Section: Introductionmentioning

confidence: 99%

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Language Localization in Cases of Left Temporal Lobe Arachnoid Cyst: Evidence against Interhemispheric Reorganization

Stowe

Pruim

et al. 2000

Brain and Language

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Section: Subjectsmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Language Localization in Cases of Left Temporal Lobe Arachnoid Cyst: Evidence against Interhemispheric Reorganization

Stowe

Pruim

et al. 2000

Brain and Language

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“…They may occur in benign conditions, when associated with a clear fluid or with malignant diseases, when they are usually filled with yellow proteinaceous fluid. Based on pathogenesis, Go et al (1993) suggested the following classification:…”

Section: Introductionmentioning

confidence: 99%

Amino acid composition of brain cysts: levels of excitatory amino acids in cyst fluid fail to predict seizures

Wieser¹,

Rudolph²,

Blau³

et al. 2003

Epilepsy Research

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Cytological diagnosis of cystic brain tumors: A retrospective study of 88 cases

Hernández

Zagzag

Kelly

et al. 2004

Diagnostic Cytopathology

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The stereotaxic aspiration of cystic brain tumors is performed to provide cyst decompression and/or to facilitate surgical resection. The purpose of our study was to determine the diagnostic value of brain cyst fluid cytology, especially in clinically suspected recurrent tumors with no histological follow-up (HF), when a diagnosis is most needed. We reviewed the cytological diagnoses of 88 aspirates from 70 patients with cystic brain tumors between 1995 and 2001, of which 31 had a prior known malignancy including 18 primary brain tumors (PBTs) and 13 adenocarcinomas (ACAs). Sixty-nine of 88 aspirates were obtained intraoperatively. Nineteen of 88 aspirates were obtained from 10 patients with recurrent or persistent cystic brain tumors (8 patients with PBT and 2 patients with ACA), with available clinicoradiological correlation (magnetic resonance imaging/computed tomography [MRI/CT] scans) in 13 of them. The 88 aspirates were classified in three categories: 28 positive (32%), 15 atypical (17%), and 45 negative (51%). Eight of 28 positive cases (5 case of PBT, 2 cases of ACA, and 1 case of melanoma) were given a nonspecific diagnosis of malignant neoplasm (9% of all cases). Fifteen of 28 positive cases (6 cases of PBT, 8 cases of ACA, and 1 case of melanoma) were diagnosed correctly and confirmed by HF (17% of all cases). Four of 28 cases were ACA diagnosed solely by cytology (<4% of all cases). One neurocytoma (1/28) case was mistaken for an oligodendroglioma despite cell blocks (CBs) and immunophenotyping (IPT) (<1% of all cases). Eleven of 15 atypical cases were 8 cases of PBT, 2 cases of ACA, and 1 case of postoperative change (PC). Four of 15 atypical cases (from three patients with suspected PBT recurrence) could not be further characterized by CB/IPT and had no HF. Twenty-seven of 45 negative cases were falsely negative (23 cases of PBT, 3 cases of ACA, and 1 case of malignant neoplasm); 11/45 cases were PC, and 7/45 (from five patients with clinically suspected tumor recurrence) cases had no HF. Cytological evaluation of brain cyst fluid is not a reliable means of diagnosing cystic brain neoplasms (including recurrences) due to a high false negative rate and a low sensitivity. Most of the negative or atypical cases (68% of all cases) were recurrent PBT of glial origin that may not be prone to exfoliate. These cytological specimens consisted of lysed blood, obscuring inflammatory cells, and degenerated diagnostic cells if any, yielding inconclusive results.

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Cystic lesions of the brain. A classification based on pathogenesis, with consideration of histological and radiological features

Cited by 52 publications

References 56 publications

Language Localization in Cases of Left Temporal Lobe Arachnoid Cyst: Evidence against Interhemispheric Reorganization

Language Localization in Cases of Left Temporal Lobe Arachnoid Cyst: Evidence against Interhemispheric Reorganization

Amino acid composition of brain cysts: levels of excitatory amino acids in cyst fluid fail to predict seizures

Cytological diagnosis of cystic brain tumors: A retrospective study of 88 cases

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