Amino acid composition of brain cysts: levels of excitatory amino acids in cyst fluid fail to predict seizures

Wieser, Heinz‐Gregor; Rudolph, Uwe; Blau, Nenad; Boison, Detlev; Imhof, Hans-Georg; Bernays, René L.; Yonekawa, Yasuhiro

doi:10.1016/s0920-1211(03)00106-2

Cited by 7 publications

(2 citation statements)

References 23 publications

(23 reference statements)

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“…Seizures are the most frequent clinical presentation of supratentorial neurenteric cysts. Epileptogenicity of brain cystic lesion is probably independent to the composition of cyst fluid, as stated by Weiser et al 23. Nevertheless they did not analyse the amino acid composition of any neurenteric cyst.…”

Section: Discussionmentioning

confidence: 94%

Supratentorial neurenteric cyst associated with a intraparenchymal subependymoma

et al. 2012

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Neurenteric cyst is a rare developmental lesion that very infrequently is localised supratentorially. Intraparenchymal subependymoma is an even more rare benign tumour. The authors report the case of a 45-year-old gentleman with a background of drug resistant epilepsy. An MRI was performed which showed a left frontal cystic lesion with a solid component. Histopathology confirmed a type C neurenteric cyst associated with an intraparenchymal subependymoma. Following enlargement of the lesion and worsening of symptoms he was referred to our institution for further management. A frontotemporal craniotomy was performed for excision of the lesion but recurrence occurred within 1 year. The lesion was further excised and 19 months post re-excision the patient is seizure free with no evidence of recurrence on MRI.

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Section: Discussionmentioning

confidence: 94%

Supratentorial neurenteric cyst associated with a intraparenchymal subependymoma

et al. 2012

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“…No increase in amino acids was observed in non-epileptogenic brain regions, findings that led the authors to suggest that drug resistance was associated with the presence of intracystic amino acids. Wieser et al (2003) [ 20 ] studied the CSF concentration of amino acids in 23 patients with arachnoid brain cysts submitted to surgery and observed that only three presented elevated levels of aspartate and/or glutamate in the cysts. Only two of these patients presented seizures before surgery.…”

Section: Discussionmentioning

confidence: 99%

Quantification of Amino Acid Neurotransmitters in Cerebrospinal Fluid of Patients with Neurocysticercosis

Camargo

Bertolucci

2015

TONEUJ

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Background : Neurocysticercosis is a parasitic disease that affects the central nervous system. Its main clinical manifestations are epileptic seizures. The objective of this study was to investigate the correlation between neurotransmitter concentrations in cerebrospinal fluid (CSF) and the different evolutive forms of neurocysticercosis with or without seizures. Methods : Neurotransmitter concentrations (Aspartate, Glutamate, GABA, Glutamine, Glycine, Taurine) were determined in CSF samples from 42 patients with neurocysticercosis divided into patients with the active cystic form (n = 24, 12 with and 12 without seizures) and patients with calcified form (n = 18, 12 with and 6 without seizures), and a control group consisting of 59 healthy subjects. Results : Alterations in amino acid concentration were observed in all patients with neurocysticercosis.Conclusion : We conclude that disturbances in amino acid metabolism accompany the presentation of neurocysticercosis. Replacement of the terms inactive cyst by reactive inactive cyst and calcification by reactive calcification is suggested.

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Epilepsy and Arachnoid Cysts

Satte¹

2023

Arachnoid Cysts

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Amino acid composition of brain cysts: levels of excitatory amino acids in cyst fluid fail to predict seizures

Cited by 7 publications

References 23 publications

Supratentorial neurenteric cyst associated with a intraparenchymal subependymoma

Supratentorial neurenteric cyst associated with a intraparenchymal subependymoma

Quantification of Amino Acid Neurotransmitters in Cerebrospinal Fluid of Patients with Neurocysticercosis

Epilepsy and Arachnoid Cysts

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