Cyprodinil: A New Fungicide with Broad-Spectrum Activity

Müller, Urs; Hubele, Adolf; Zondler, Helmut; Herzog, J.

doi:10.1021/bk-1998-0686.ch024

Cited by 9 publications

(4 citation statements)

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“…The fungicide fluazinam (23), an uncoupler of the oxidative phosphorylation, was found during a synthesis campaign with the aim to improve the profile of the structurally related acaricide fentrifanil (22). Fluazinam is used for the control of diverse diseases in fruits and vegetables, especially downy mildews and molds.…”

Section: Fungicides Originating From Insecticide Acaricide and Nemati...mentioning

confidence: 99%

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The power of cross‐indication testing: agrochemicals originally stemming from a different indication

Lamberth

2022

Pest Management Science

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Cross‐indication testing is the assaying of final compounds, but also their intermediates or side products, from one agrochemical indication against target species of other product lines. This approach has proven to be a highly successful source of lead compounds, which led to several important crop protection products. This review article describes, which herbicides came from fungicides and insecticides, how fungicides have been obtained from herbicide and insecticide leads and which insecticides have their roots in herbicide and fungicide chemistry. © 2022 Society of Chemical Industry.

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Section: Fungicides Originating From Insecticide Acaricide and Nemati...mentioning

confidence: 99%

“…Cyprodinil belongs to the methionine biosynthesis inhibiting anilinopyrimidine fungicides and shows potent efficacy against different Ascomycetes pathogens, such as Botrytis cinerea , causal agent of gray mold, and Alternaria solani , causal agent of early blight (Scheme 3). 21,22 …”

Section: Fungicides Originating From Herbicide Leadsmentioning

confidence: 99%

The power of cross‐indication testing: agrochemicals originally stemming from a different indication

Lamberth

2022

Pest Management Science

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“…For example, the methionine synthesis-inhibiting fungicide cyprodinil (Figure 2) was discovered by derivatization of an acetolactate synthase (ALS) inhibitor herbicide. 8,9 Lamberth discusses other examples of fungicides derived from herbicides, but without the same molecular targets. 5 However, there is one case of molecular site overlap that led to the development of a herbicide from a fungicide.…”

Section: ■ Introductionmentioning

confidence: 99%

“…However, this approach does not consider the molecular target of the starting compound, and the result of this strategy is often a compound with a molecular target on the second pest type different from that on the starting pest type. For example, the methionine synthesis-inhibiting fungicide cyprodinil (Figure ) was discovered by derivatization of an acetolactate synthase (ALS) inhibitor herbicide. , Lamberth discusses other examples of fungicides derived from herbicides, but without the same molecular targets . However, there is one case of molecular site overlap that led to the development of a herbicide from a fungicide.…”

Section: Introductionmentioning

confidence: 99%