Cypermethrin synergism by pyrethroid esterase inhibitors in adults of the whitefly Bemisia tabaci

Ishaaya, I.; Mendelson, Zmira; Ascher, K. R. S.; Casida, John E.

doi:10.1016/0048-3575(87)90014-9

Cited by 46 publications

(30 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, several other B. tabaci strains, homozygous for the AChE-R allele, have shown significantly higher resistance than the original AChE-R strain analyzed, suggesting the involvement of at least one additional mechanism (Denholm et al, 1998). Esterase-based resistance was the most likely explanation because profenofos has been shown to be sequestered by esterases in an OPresistant strain of B. tabaci (Byrne and Devonshire, 1991), and also to inhibit pyrethroid hydrolyzing esterases (Ishaaya et al, 1987). Additional evidence for this type of resistance has been driven primarily from associations between increased levels of esterase activity and the expression of resistance (Dittrich et al, 1990) or the ability of specific esterase-inhibiting synergists to restore the toxicity of OPs in bioassays of resistant populations (Prabhaker et al, 1988).…”

Section: Introductionmentioning

confidence: 88%

Organophosphates' resistance in the B-biotype of Bemisia tabaci (Hemiptera: Aleyrodidae) is associated with a point mutation in an ace1-type acetylcholinesterase and overexpression of carboxylesterase

Alon

Nauen

et al. 2008

Insect Biochemistry and Molecular Biology

165

124

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 88%

Organophosphates' resistance in the B-biotype of Bemisia tabaci (Hemiptera: Aleyrodidae) is associated with a point mutation in an ace1-type acetylcholinesterase and overexpression of carboxylesterase

Alon

Nauen

et al. 2008

Insect Biochemistry and Molecular Biology

165

124

View full text Add to dashboard Cite

“…Specific research on the esterases involved revealed different degrees of substrate specificity toward the pyrethroids or their isomers (Chang and Whalon 1987;. Inhibition of the esterases by organophpsphorus insecticides (Ishaaya et al 1987) or formamidine insecticides (Kamel et al 1987) contributes to the synergism of pyrethroids by these other insecticides. Resistance or tolerance of the brown plant hopper and whitefly may be in large part due to esterases that detoxify pyrethroids.…”

Section: Biotransformationmentioning

confidence: 98%

Comparative Toxicology of the Pyrethroid Insecticides

Bradbury¹,

Coats

1989

Reviews of Environmental Contamination and Toxicology

274

142

View full text Add to dashboard Cite

“…[3], Spodopteva eridanra 1151 and T . ni [2,16], and in whiteflies [6]. However, the esterase inhibitor profenofos was not synergistic with any of the cyanopyrethroids for Triboliuriz castaneum larvae.…”

Section: Pyrethroid Detoxification and Synergismmentioning

confidence: 91%

“…4). According to log dose-probit mortality plots, monocrotophos synergized the toxicity of cypermethrin about 50-and 38-fold at 3 and 10 days after treatment, respectively [6]. [3], Spodopteva eridanra 1151 and T .…”

Section: Pyrethroid Detoxification and Synergismmentioning

confidence: 99%

Insect detoxifying enzymes: Their importance in pesticide synergism and resistance

Ishaaya

1993

Arch Insect Biochem Physiol

Self Cite

View full text Add to dashboard Cite

Pyrethroid esterases of Trichoplusia ni, Spodoptera littoralis and Bemisia tabaci hydrolyze the trans-isomers of various pyrethroids more extensively than the cis-isomers. Profenofos fed to T. ni larvae at a level inhibiting the gut pyrethroid esterases by 65% with trans-permethrin and of 95% with cis-cypermethrin increased the toxicity of topically applied trans-permethrin by fourfold and cis-cypermethrin by 20-fold. Similar assays with S. littoralis resulted in an increase of about threefold in the toxicity of both compounds. Monocrotophos, profenofos, acephate, and methidathion inhibited pyrethroid esterase activity in B. tabaci and synergized considerably the toxicity of cypermethrin. The remarkable tolerance of the predator Chrysopa carnea to pyrethroids is attributed to the presence of a high level of pyrethroid esterase activity with a unique specificity for hydrolyzing the cis-isomer. Phenyl saligenin cyclic phosphonate, a potent inhibitor for larval pyrethroid esterases synergized the toxicity of trans-permethrin by 68-fold from an LD50 of 17,000 micrograms/g to 250 micrograms/g. In contrast, oxidase inhibitors such as piperonyl butoxide, SV-1, and MPP synergized considerably the toxicity of pyrethroids in Tribolium castaneum and Musca domestica. Hence the predominant pathway for pyrethroid detoxification in insects, whether hydrolytic or oxidative, depends largely on the insect species. The high toxicity of the recent developed acylureas results from their high retention in the insects. Assays using radiolabeled diflubenzuron and chlorfluazuron applied to fourth instar T. castaneum larvae revealed a rapid elimination of diflubenzuron (T1/2 approximately equal to 7 h) as compared with chlorfluazuron (T1/2 > 100 h). Addition of 100 ppm DEF to the diet increased both the retention time and the toxicity of diflubenzuron in both T. castaneum and S. littoralis, which was due probably to the inhibition of diflubenzuron hydrolase activity. Esterases, hydrolyzing pyrethroids, and acylureas may serve as tools for evaluating potential synergists and for monitoring resistance in various agricultural pests due to increased metabolism.

show abstract

Cypermethrin synergism by pyrethroid esterase inhibitors in adults of the whitefly Bemisia tabaci

Cited by 46 publications

References 13 publications

Organophosphates' resistance in the B-biotype of Bemisia tabaci (Hemiptera: Aleyrodidae) is associated with a point mutation in an ace1-type acetylcholinesterase and overexpression of carboxylesterase

Organophosphates' resistance in the B-biotype of Bemisia tabaci (Hemiptera: Aleyrodidae) is associated with a point mutation in an ace1-type acetylcholinesterase and overexpression of carboxylesterase

Comparative Toxicology of the Pyrethroid Insecticides

Insect detoxifying enzymes: Their importance in pesticide synergism and resistance

Contact Info

Product

Resources

About