Cyclodextrins as Supramolecular Hosts for Organometallic Complexes

New Phosphane Based on a β‐Cyclodextrin, Exhibiting a Solvent‐Tunable Conformation, and its Catalytic Properties

“…For the catalytic system [Rh- 2 ]BF 4 /PM-b-CD-PPh 2 , the conversion was low at 20 8C and it was necessary to increase the temperature up to 60 8C to reach high conversion after 4 h ( Table 1, entries 1 and 2). When 2 ] was used as a catalytic precursor, the conversion was four times lower ( Table 1, entry 3).…”

“…When 2 ] was used as a catalytic precursor, the conversion was four times lower ( Table 1, entry 3). The increase in PM-b-CD-PPh 2 /Rh ratio decreased the conversion; indeed the catalytic species are the most stable and, therefore, the least active (Table 1, entry 4).…”

Enantioselective Transfer Hydrogenation of Aliphatic Ketones Catalyzed by Ruthenium Complexes Linked to the Secondary Face of β‐Cyclodextrin

“…Beautiful examples have been reported [3][4] which could be classified as systems in which the cyclodextrins act as first-and transient second-sphere ligand. [5] We report here on a new supramolecular catalyst in which a b-cyclodextrin derivative provides the first ligand sphere for ruthenium, simultaneously binds lipophilic molecules and participates in orientation and activation of the substrates. Such a system could be useful for the enantioselective reduction of non-conjugated ketones by ruthenium complex-catalyzed hydrogen transfer reactions which still remain a challenge.…”

Crystal Structure of β‐Cyclodextrin‐Felbinac Inclusion Complex

“…It has a hydrophilic exterior and a hydrophobic central cavity, which results in its ability to form inclusion complexes with a variety of hydrophobic molecules in aqueous solution. [3][4][5][6] The physicochemical properties of the included molecules are different from the uncomplexed ones. This beneficial property has been applied to the pharmaceutical field, 7,8 and several studies have been performed on felbinac.…”