Cyclodextrin-containing layer-by-layer films and microcapsules: Synthesis and applications

Akiba, Uichi; Anzai, Jun Ichi

doi:10.3934/matersci.2017.4.832

Cited by 7 publications

(7 citation statements)

References 87 publications

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“…PAs were first synthesized in 2008 by Ogoshi and coworkers as a novel class of host compounds [ 54 , 55 ]. Diamino-pillar[5]arene (diamino-PA[5]) and dicarboxyl-pillar[ 5 ]arene (dicarboxyl-PA[5]) ( Figure 4 ) were alternately deposited on the surface of quartz plates to form LbL films through electrostatic affinity [ 56 ]. UV-VIS absorption spectroscopy revealed the successful preparation of PA[5] multilayer films.…”

Section: Ca[ N ]-Containing Lbl Filmsmentioning

confidence: 99%

“…LbL deposition affords stratified multilayer architectures on the surface. A variety of interactions, such as hydrogen bonds [ 3 , 4 ], host-guest complexations [ 5 ], charge-transfer (CT) interactions [ 6 ], DNA hybridization [ 7 ], covalent bonds [ 8 ], and protein-ligand affinity [ 9 ] are available as the driving forces for the construction of films. Consequently, both synthetic polymers and biomaterials, which include proteins [ 10 , 11 ], polysaccharides [ 12 , 13 ], and DNA [ 14 , 15 ], are often used as components of LbL films.…”

Section: Introductionmentioning

confidence: 99%

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Host-Guest Chemistry in Layer-by-Layer Assemblies Containing Calix[n]arenes and Cucurbit[n]urils: A Review

2018

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Section: Ca[ N ]-Containing Lbl Filmsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Host-Guest Chemistry in Layer-by-Layer Assemblies Containing Calix[n]arenes and Cucurbit[n]urils: A Review

2018

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“…However, their use as a film component involves some limitations, like low water absorption capacity, high molecular weight, and possible parenteral toxicity, which limits the amount of CD to be used. To overcome these limitations, an alternative is to add a polysaccharide to the polymeric matrix [ 6 , 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

Manifest/Non-Manifest Drug Release Patterns from Polysaccharide Based Hydrogels—Case Study on Cyclodextrin—κ Carrageenan Crosslinked Hydrogels

et al. 2021

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The aim of this study is to offer a comprehensive view on drug release from hydrogel, from both an experimental and a theoretical point of view. Aiming to benefit cyclodextrins’ properties (not irritant; stable; able to modify the physical, chemical and biological properties of active compounds; accessible at low prices) and those of carrageenan polysaccharide (antitumor, immunomodulatory, antihyperlipidemic, anticoagulant, biocompatibility, biodegradability), original hydrogel films based on beta cyclodextrin and kappa carrageenan using epichlorohydrin as crosslinking agent were prepared and characterized from morphological and physical/chemical points of view. The results (morphology, the swelling degree, and the loading/release capacity) proved their potential as carriers for different types of drugs. Further, a new theoretical model, from a multifractal paradigm of motion, was proposed for the drug release from hydrogel films, starting from the fundaments of its evolution at a microscopic level, and aiming to obtain information on system evolution, at both the spatial and temporal scales, inapproachable by quantitative measurements.

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“…Other molecular interactions such as charge-transfer (CT) interactions [ 21 ], DNA hybridization [ 22 ], host-guest complexations [ 23 ], π-cation interactions [ 24 ], coordination bonds [ 25 ], and covalent bonds [ 26 ] are also available as binding forces for the construction of LbL films. These molecular interactions are characterized by the high selectivity in binding.…”

Section: Introductionmentioning

confidence: 99%

“…For example, nucleotide chains with complementary base pairs can be hybridized to form LbL films [ 22 ]. Similarly, only the guest compounds with suitable shape and size are included in the cavity of host molecules in the films [ 23 ]. In addition, specifically designed polymers have to be synthesized to construct LbL films based on these molecular interactions.…”

Section: Introductionmentioning

confidence: 99%

Photosensitive Layer-by-Layer Assemblies Containing Azobenzene Groups: Synthesis and Biomedical Applications

2017

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Abstract:This review provides an overview of the syntheses of photosensitive layer-by-layer (LbL) films and microcapsules modified with azobenzene derivatives and their biomedical applications. Photosensitive LbL films and microcapsules can be prepared by alternate deposition of azobenzene-bearing polymers and counter polymers on the surface of flat substrates and microparticles, respectively. Azobenzene residues in the films and microcapsules exhibit trans-to-cis photoisomerization under UV light, which causes changes in the physical or chemical properties of the LbL assemblies. Therefore, azobenzene-functionalized LbL films and microcapsules have been used for the construction of photosensitive biomedical devices. For instance, cell adhesion on the surface of a solid can be controlled by UV light irradiation by coating the surface with azobenzene-containing LbL films. In another example, the ion permeability of porous materials coated with LbL films can be regulated by UV light irradiation. Furthermore, azobenzene-containing LbL films and microcapsules have been used as carriers for drug delivery systems sensitive to light. UV light irradiation triggers permeability changes in the LbL films and/or decomposition of the microcapsules, which results in the release of encapsulated drugs and proteins.

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Cyclodextrin-containing layer-by-layer films and microcapsules: Synthesis and applications

Cited by 7 publications

References 87 publications

Host-Guest Chemistry in Layer-by-Layer Assemblies Containing Calix[n]arenes and Cucurbit[n]urils: A Review

Host-Guest Chemistry in Layer-by-Layer Assemblies Containing Calix[n]arenes and Cucurbit[n]urils: A Review

Manifest/Non-Manifest Drug Release Patterns from Polysaccharide Based Hydrogels—Case Study on Cyclodextrin—κ Carrageenan Crosslinked Hydrogels

Photosensitive Layer-by-Layer Assemblies Containing Azobenzene Groups: Synthesis and Biomedical Applications

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