Cyanoacrylate adhesive use in primary operation and reoperation in rabbit eye muscle surgery

Campomanes, Alejandra G. de Alba; Lim, Annie K.; Fredrick, Douglas R.

doi:10.1016/j.jaapos.2009.04.015

Cited by 9 publications

(4 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In 2009, a study was performed in rabbits to evaluate the use of a new long chain cyanoacrylate tissue adhesive 90. It provided tensile strength similar to older generations but with an inflammatory reaction rate closer to fibrin.…”

Section: Strabismus Surgerymentioning

confidence: 99%

Surgical adhesives in ophthalmology: history and current trends

et al. 2018

View full text Add to dashboard Cite

Tissue adhesives are gaining popularity in ophthalmology, as they could potentially reduce the complications associated with current surgical methods. An ideal tissue adhesive should have superior tensile strength, be non-toxic and anti-inflammatory, improve efficiency and be cost-effective. Both synthetic and biological glues are available. The primary synthetic glues include cyanoacrylate and the recently introduced polyethylene glycol (PEG) derivatives, while most biological glues are composed of fibrin. Cyanoacrylate has a high tensile strength, but rapidly polymerises upon contact with any fluid and has been associated with histotoxicity. Fibrin induces less toxic and inflammatory reactions, and its polymerisation time can be controlled. Tensile strength studies have shown that fibrin is not as strong as cyanoacrylate. While more research is needed, PEG variants currently appear to have the most promise. These glues are non-toxic, strong and time-effective. Through MEDLINE and internet searches, this paper presents a systematic review of the current applications of surgical adhesives to corneal, glaucoma, retinal, cataract and strabismus surgeries. Our review suggests that surgical adhesives have promise to reduce problems in current ophthalmic surgical procedures.

show abstract

Section: Strabismus Surgerymentioning

confidence: 99%

Surgical adhesives in ophthalmology: history and current trends

et al. 2018

View full text Add to dashboard Cite

show abstract

“…However, obtaining positive results in wound healing has been a difficult task ( Ryou and Thompson 2002;Neto et al 2008;Sangwan et al 2014;Li et al 2019;Vanerio et al 2019;Hamedi et al 2022). Negative effects of suturing occur due to more tension in stitches and placement of stitches for a long time upon wound area (Chan et al 2002;Campomanes et al 2009;Barton et al 2013;Daykan et al 2017;Rodrigues et al 2022;Huang et al 2023). Tight stitches produce imprints along with stitch line and lead to inside growth of epidermis (Gabay et al 2011;Hussain et al 2016;Lee et al 2022;Zhao et al 2022).…”

Section: Introductionmentioning

confidence: 99%

Comparison of Photosensitized Tissue Bonding and Vet Glue in Closure of Incisional Wounds

2023

Agrobiol. Records

View full text Add to dashboard Cite

Photochemical tissue bonding (PTB) is considered to be used in surgery to enhance healing of cutaneous wounds and to minimize the complications i.e., wound dehiscence, inflammatory reactions, and infections affecting animal health. The aim of this study is to analyze the wound healing process by using PTB and cyanoacrylate-based tissue adhesive. The results showed that PTB group had quicker healing time, good healing score and stronger tensile strength for incisional wounds of rabbits. However, Vetbond group showed delayed healing, poor healing score, and weaker tensile strength. The 14-days post-surgery PTB treated rabbits cutaneous layers were stained with hematoxylin and eosin stain. The histological examinations of these cutaneous specimens revealed higher thicknesses (μm) of regenerated Epidermal, Dermal and Hypodermal layers, collagen fibers, and epithelial ridges. Whereas, for 14 days Vetbond treated rabbits cutaneous layers showed less thickness of these cutaneous layers, degenerated collagen fibers and no ridges. In future, large-scale analysis of combined suture less technique is required to enhance wound healing processes.

show abstract

“…Not all materials that are used for implants possess these properties. Many polymers or metals are too rigid and almost impossible to suture, so adhesion between the rigid implant and the native tissue is achieved by cyanoacrylate glue or fibrin glue, which bond the tissue in situ . However, clinical tissue adhesives are faced with challenges regarding adhesion strength, toxicity, and biocompatibility .…”

Section: Introductionmentioning

confidence: 99%

Adhesion between polymer surface modified by graft polymerization and tissue during surgery using an ultrasonically activated scalpel device

Nam

Iwata

Kimura

et al. 2014

J of Applied Polymer Sci

View full text Add to dashboard Cite

In the field of surgery, achieving adhesion between a polymer implant and tissue poses a challenge considering that suturing is not appropriate for the stability of such implants. An ultrasonically activated scalpel that generates heat by mechanical vibration and promotes adhesion between a polymer implant and native tissue by pressing the two materials together has very good potential for application in the field. To determine the type of polymer that is suitable for the purpose, we investigated polyethylene (PE) and polystyrene (PS) films, the surfaces of which were activated by corona discharge. Graft polymerization was then performed on the corona‐treated surfaces to vary their properties. The corona‐treated PE and PS films grafted with poly(acrylic acid), poly(methacrylic acid), poly(vinyl benzylacrylic acid), and poly(hydroxylethyl acrylate), respectively, adhered to the tissue when the ultrasonically activated scalpel was applied. The heat generated by the mechanical vibration and the applied pressure enabled the carboxyl or hydroxyl groups to bond with the proteins in the extracellular matrix. We therefore concluded that it was possible to integrate this technique in the development of new types of polymer devices that could be stably implanted in a living body. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40885.

show abstract

Cyanoacrylate adhesive use in primary operation and reoperation in rabbit eye muscle surgery

Cited by 9 publications

References 13 publications

Surgical adhesives in ophthalmology: history and current trends

Surgical adhesives in ophthalmology: history and current trends

Comparison of Photosensitized Tissue Bonding and Vet Glue in Closure of Incisional Wounds

Adhesion between polymer surface modified by graft polymerization and tissue during surgery using an ultrasonically activated scalpel device

Contact Info

Product

Resources

About