Cutaneous temperature and pressure pain threshold in individuals with knee osteoarthritis

Alfieri, Fábio Marcon; Silva, Natália Cristina de Oliveira Vargas e; Santos, Antonio Carlos; Battistella, Linamara Rizzo

doi:10.5114/reum.2020.100195

Cited by 8 publications

(10 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Lower PPTs have been described as a risk factor for worsening knee OA symptoms and pain conditions [ 38 ]. PPT values in the present study were consistent with the values in previous studies of patients with knee OA [ 39 ]. The PPTs increased significantly in the TENS and IFC groups compared with the placebo groups after treatment and the third month compared with the baseline.…”

Section: Discussionsupporting

confidence: 92%

Comparison of the effects of transcutaneous electrical nerve stimulation and interferential current therapies in central sensitization in patients with knee osteoarthritis

Artuç,

Uçkun,

Sivas

et al. 2023

Korean J Pain

View full text Add to dashboard Cite

Background: This study is primarily aimed to determine whether transcutaneous electrical nerve stimulation (TENS) and interferential current (IFC) treatments have any effect on central sensitization (CS) in patients with knee osteoarthritis (OA) and to investigate which treatment is more effective. Methods: In this randomized controlled trial, 80 patients were randomized into four treatment groups: TENS, Plasebo-TENS, IFC, and Plasebo-IFC. All interventions were applied 5 times a week for 2 weeks. Primary outcome was pressure pain threshold (PPT), which is accepted as the objective indicator of CS, at the painful knee and at the shoulder as a painless distant point. Other outcome measures were the visual analog scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index, Timed Up and Go Test, pain catastrophizing scale, Beck Depression Inventory, and Tampa Scale of Kinesiophobia. Results: All assessment parameters were improved, without a significant difference among the groups except PPT. PPT scores were significantly improved in TENS and IFC groups when compared with the sham groups at 2 weeks and 3 months. In addition, this improvement was even more pronounced in the TENS group. Multivariable logistic regression analysis showed that the patient's inclusion in the TENS group, an initial high PPT, and an initial low VAS score were independent risk factors for improvement in the PPT. Conclusions: This study shows that TENS and IFC reduced pain sensitivity as compared to placebo groups in patients with knee OA. This effect was more pronounced in the TENS group.

show abstract

Section: Discussionsupporting

confidence: 92%

Comparison of the effects of transcutaneous electrical nerve stimulation and interferential current therapies in central sensitization in patients with knee osteoarthritis

Artuç,

Uçkun,

Sivas

et al. 2023

Korean J Pain

View full text Add to dashboard Cite

show abstract

“…This initial significant ΔST can be explained by the underlying knee osteoarthritis characterizing the majority of patients that arrive for TKA. Previous studies report that osteoarthritis causes elevated ST compared to the unaffected knee (0.1–0.6 °C) 8 , 25 , 26 . However, patients with bilateral osteoarthritis, or other bilateral pathologies such as rheumatoid arthritis, may not show this difference 27 .…”

Section: Discussionmentioning

confidence: 92%

“…Infrared thermography is a noninvasive method that has been used in a variety of clinical entities to measure skin temperature distribution 5 . The latter is subtended by microcirculatory blood flow 6 which is altered in inflammatory processes such as osteoarthritis 7 , 8 , infections 9 , or as a normal physiological response following surgical procedures. Incisions of the skin, muscle, and bone have been shown to be associated with an increase in C-reactive protein (CRP) and pro-inflammatory cytokines as well as local edema–all of which can contribute to increases in skin temperature (ST) 10 , 11 .…”

Section: Introductionmentioning

confidence: 99%

Natural history of changes in knee skin temperature following total knee arthroplasty: a systematic review and meta-analysis

Gavish

Kandel

Rivkin

et al. 2023

Sci Rep

View full text Add to dashboard Cite

Patients undergoing total-knee arthroplasty (TKA) have transient increases in anterior knee skin temperature (ST) that subside as recovery progresses–except in cases of systemic or local prosthetic joint infections (PJI). This meta-analysis was designed to quantify the changes in knee ST following TKA in patients with uncomplicated recovery as a prerequisite for assessing the usefulness of thermal imaging for diagnosis of PJI. This meta-analysis (PROSPERO-CRD42021269864) was performed according to PRISMA guidelines. PUBMED and EMBASE were searched for studies reporting knee ST of patients that underwent unilateral TKA with uncomplicated recovery. The primary outcome was the weighted means of the differences in ST between the operated and the non-operated knees (ΔST) for each time point (before TKA, and 1 day; 1,2, and 6 weeks; and 3,6, and 12-months post-TKA). For this analysis, 318 patients were included from 10 studies. The elevation in ST was greatest during the first 2-weeks (ΔST = 2.8 °C) and remained higher than pre-surgery levels at 4–6 weeks. At 3-months, ΔST was 1.4 °C. It decreased to 0.9 °C and 0.6 °C at 6 and 12-months respectively. Establishing the baseline profile of knee ST following TKA provides the necessary first step for evaluating the usefulness of thermography for the diagnosis of post-procedural PJI.

show abstract

“…(≈3 °C) often occurs in the articular cartilage of OA patients. [94] An even more significant thermal difference between the lesion and normal tissue can be potentially promoted using the near-infrared ray (NIR) photothermal [95,96] or magnetocaloric effects, [97] or via high-intensity focused ultrasound.…”

Section: Thermal Responsive In Situ Drug Delivery Nanoplatforms For O...mentioning

confidence: 99%

Stimulus‐Responsive Drug Delivery Nanoplatforms for Osteoarthritis Therapy

Jiang

Zhang

2023

Small

View full text Add to dashboard Cite

Fundamentally degenerative, OA represents a considerably negative impact on the quality of life. [1,2] With an increasingly aging global population, greater numbers of OA patients are representing a clear increase in economic and societal burden. OA is primarily characterized by the degeneration or deterioration of articular cartilage. [3] More specifically, as a result of the excessive recruitment of inflammatory cells at the joint site, [4] matrix metalloproteinase (MMP) [5] and a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) [6] are overexpressed during the development of OA, which leads to the destruction of the collagen II network and glycosaminoglycan (GAG). Articular cartilage dysfunction and degradation then eventually result, often presenting with permanent pathologic alterations to the entire joint.Current pharmacological treatments, (primarily focused on pain relief and antiinflammation), and/or surgery, (including microfracture surgery and joint replacement), are the most conventional therapeutic approaches for OA. [1,7] There are several disadvantages to these conventional approaches. Whilst microfracture surgery provides a measure of relief and functional recovery of the smaller-scale joint defects through the local generation of fibrocartilage from bone marrow obtained from the subchondral bone, due to the lower abrasion-resistance ability of fibrocartilage this method is often unsuitable to provide long-term relief, or for situations where large-scale defects have occurred. [8] A number of clinical strategies of joint replacement, including osteochondral autografts or allografts, are also limited by the restricted availability of donor grafts or by complications requiring secondary surgery. [9] Along with the continued development of surgical treatments, more advanced therapeutic methods have also been developed for OA surgery. These include ACI (autologous chondrocyte implantation) and MACI (matrix-induced autologous chondrocyte implantation). However, for ACI, the viability and loss of chondrocytes during the planting procedure seem to be an unavoidable problem. MACI was developed as a potential solution to this, where the in vitro use of a biodegradable (collagen matrix membrane) material as a temporary scaffold for the pre-plantation of chondrocytes could effectively lessen the loss of cells during the process of transplantation. However, for patients of more advanced ages or with too large an area of injury to the cartilage, MACI remains an unsuitable therapeutic approach.Osteoarthritis (OA) is one of the most prevalent age-related degenerative diseases. With an increasingly aging global population, greater numbers of OA patients are providing clear economic and societal burdens. Surgical and pharmacological treatments are the most common and conventional therapeutic strategies for OA, but often fall considerably short of desired or optimal outcomes. With the development of stimulus-responsive nanoplatforms has come the potential for improved therapeutic strategies for...

show abstract

Cutaneous temperature and pressure pain threshold in individuals with knee osteoarthritis

Cited by 8 publications

References 22 publications

Comparison of the effects of transcutaneous electrical nerve stimulation and interferential current therapies in central sensitization in patients with knee osteoarthritis

Comparison of the effects of transcutaneous electrical nerve stimulation and interferential current therapies in central sensitization in patients with knee osteoarthritis

Natural history of changes in knee skin temperature following total knee arthroplasty: a systematic review and meta-analysis

Stimulus‐Responsive Drug Delivery Nanoplatforms for Osteoarthritis Therapy

Contact Info

Product

Resources

About