Cutaneous T-Cell Lymphoma Epidemiology

Lessin, Stuart R.

doi:10.1001/archderm.143.7.916

Cited by 7 publications

(3 citation statements)

References 21 publications

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“…An increase in MF incidence in the recent past has been attributed to more awareness of the disease and improved diagnostic facilities. 2,7,19,20 MF has been reported to be more common in the middle-aged patients and rare below the age 20 years. In our series, 62% of the patients were diagnosed by the age 40 years.…”

Section: Resultsmentioning

confidence: 99%

Clinicoepidemiological features of mycosis fungoides in Kuwait, 1991–2006

et al. 2010

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Section: Resultsmentioning

confidence: 99%

Clinicoepidemiological features of mycosis fungoides in Kuwait, 1991–2006

et al. 2010

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“…Earlier studies have found that the peak age at presentation of the disease was 55-60 years. [ 22 23 ] Although MF usually affects older adults with a median age of more than 50 years, it was lower in a study in Singapore (33 years),[ 24 ] and a study in Kuwait (35.2 years). [ 25 ] In our series, the mean age of diagnosis in our patients was lower than that reported from the West (between the fourth decade and sixth decade)[ 26 27 ] and Turkey (45.6 years).…”

Section: Discussionmentioning

confidence: 99%

Primary cutaneous lymphomas: A clinical and histological study of 99 cases in Isfahan, Iran

et al. 2015

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Background:Primary cutaneous lymphomas (PCLs) represent a heterogeneous group of T- and B-cell lymphomas that present in the skin with no evidence of extracutaneous disease at the time of diagnosis. The aim of this study was to assess and report the epidemiological characteristics of PCLs in Isfahan, Isfahan Province, Iran – as a main province of Iran.Materials and Methods:A total of 99 patients were recruited over a recent 10-year period (2003-2013) with diagnosis of PCLs; the patients were classified according to the The World Health Organization/European Organization for Research and Treatment of Cancer (WHO-EORTC) criteria. Mean and standard deviations (SDs) were used to describe continuous data, numbers, and percentages for categorical data. Statistical significance was defined as P < 0.05.Results:The patients comprised 45 men and 54 women aged 5-80 years (median 36) at diagnosis. The male-to-female ratio was 1:1.2. Histological examination showed features of primary cutaneous B-cell lymphomas (PCBCLs) in four cases. The mean ± SD age in primary cutaneous T-cell lymphomas (PCTCLs) and PCBCLs was 37.9 ± 16.5 years and 39.7 ± 9.1 years, respectively (P = 0.72). The mean ± SD latent period between the time of diagnosis and initiation of skin lesions in men and women was 2.3 ± 4.1 years and 5.9 ± 10.1 years, respectively (P = 0.02). The most frequent subtypes were mycosis fungoides (MFs) (86.9%) followed by Sιzary syndrome (SS) (4%). Five patients died from PCL-related deaths.Conclusion:The distinguishing epidemiologic characteristics of PCL in Iran are the absence of a male predominance and a lower age of diagnosis. The study highlights the ethnic or regional variations in the clinicoepidemiological characteristics of PCLs.

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“…There was a higher incidence of primary CTCLs and MF in the fourth to sixth decades. Earlier studies have found that the peak age at presentation of the disease was 55–60 years [ 12 , 13 ]. Although MF usually affects older adults with a median age of more than 50 years, median ages of 33 (Singapore) [ 14 ] and 35.2 (Kuwait) [ 15 ] years have also been reported.…”

Section: Discussionmentioning

confidence: 99%

Characteristics of Primary Cutaneous T-Cell Lymphoma in Iran: A 10-Year Retrospective Study

Naeini

Sadeghiyan

Pourazizi

et al. 2014

International Scholarly Research Notices

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Background. Primary cutaneous T-cell lymphomas (CTCLs) are a group of extranodal non-Hodgkin lymphomas that may be present in the skin without any evidence of extracutaneous disease. The aim of this study was to evaluate the epidemiological characteristics of primary CTCL in Isfahan, Iran. Method. A total of 95 patients who were diagnosed as having primary CTCL were recruited during a 10-year period (2003–2013) and were classified according to the new WHO-EORTC criteria. Results. The patient group consisted of 43 (44.8%) males and 53 (55.2%) females, which indicated a female predominance (M : F ratio 1 : 1.2). The mean age at the time of diagnosis was 41.78 ± 16.88 years (range: 7–84 years). Prior to diagnosis, the lesions had persisted for a mean of 8.34 ± 4.38 years (range: 0–55 years). The age at peak diagnosis was 20–40 years (43%). The most frequent subtypes were mycosis fungoides (MF) (88.5%). Four patients died from CTCL-related complications. Conclusions. The distinguishing epidemiologic characteristics of primary CTCL, particularly those MF, in Iran, are the absence of a male predominance and lower age at diagnosis. This is likely because of the characteristic ethnic group diversity and increased susceptibility among younger population.

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Cutaneous T-Cell Lymphoma Epidemiology

Cited by 7 publications

References 21 publications

Clinicoepidemiological features of mycosis fungoides in Kuwait, 1991–2006

Clinicoepidemiological features of mycosis fungoides in Kuwait, 1991–2006

Primary cutaneous lymphomas: A clinical and histological study of 99 cases in Isfahan, Iran

Characteristics of Primary Cutaneous T-Cell Lymphoma in Iran: A 10-Year Retrospective Study

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