Cutaneous spreading of parathyroid carcinoma after fine needle aspiration cytology

Spinelli, Claudio; Bonadio, Angelo Giovanni; Berti, Piero; Materazzi, Gabriele; Miccoli, Paolo

doi:10.1007/bf03343718

Cited by 92 publications

(53 citation statements)

References 10 publications

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“…First, the diagnosis of parathyroid carcinoma can be extremely difficult histologically and sampling error may lead to false-negatives, thus misleading the surgeon preoperatively. Second, by violating the capsule of the tumor there is a risk of seeding parathyroid cells [20,21].…”

Section: Resultsmentioning

confidence: 99%

Parathyroid carcinoma: a 16-year experience in a single institution

et al. 2010

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Section: Resultsmentioning

confidence: 99%

Parathyroid carcinoma: a 16-year experience in a single institution

et al. 2010

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“…Larger volumes are less tolerated and add a significant risk of complications. Additionally, there is always the possibility to implant parathyroid carcinoma in the needle tract (16,17). In fact, this was a potential complication in the present case, but the procedure was considered the last available palliative method at that time.…”

confidence: 79%

Ethanol injection under ultrasound guidance to palliate unresectable parathyroid carcinoma

Montenegro

Chammas

Juliano

et al. 2008

Arq Bras Endocrinol Metab

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Background: Severe hypercalcemia is the leading cause of death in patients with parathyroid carcinoma. Non-curative resection and pharmacological measures may be useful for palliation in cases with recurrent and metastatic disease. Palliative treatment with intra-neoplastic ethanol injection has not been reported yet. Methods: Ultrasound-guided percutaneous alcohol injection in one patient with unresectable parathyroid carcinoma is reported. Results: One male patient with extensive recurrent parathyroid carcinoma suffering from severe hypercalcemia, refractory to all available medical measures has undergone two percutaneous ethanol injections. No major complications ensued and parathormone levels decreased from 2,990 pg/mL to 2,230pg/ml after the first injection, and to 1,104pg/mL after the second one. Calcium levels decreased from 19.8 mg/dL to 16.1 mg/dL and to 14.5 mg/dL, respectively. The patient died of metabolic hypercalcemia complications about two months later, probably due to mediastinal disease progression. Conclusion: Ultrasound-guided percutaneous ethanol injection may be employed to palliate parathyroid carcinoma in selected cases, with a transitory decrease in PTH and calcium levels. Arq Bras Endocrinol Metab 2008; 52/4:707-711)

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“…A cell spreading along the biopsy tract has also been described (29). This is a rare case of non-functioning cystic parathyroid cancer misdiagnosed prior to surgery as a cystic thyroid nodule.…”

confidence: 83%