Cutaneous Presentation of Neuroblastoma in 8 Months Old Boy: A Rare Case Report

Abstract

Background: Neuroblastoma is the neurogenic, extracranial solid tumor of infancy and children emerging anywhere along with the peripheral sympathetic nervous system. Methods: An eight months old boy presented with chief complaints of sub-cutaneous non-tender nodule on the flexor aspect of forearm, pain and fullness of abdomen, emesis, mild bone pain. Complete blood profile and other biochemical parameter were within normal limits. Results: Fine needle aspiration cytology revealed tumour cells having high nucleo-cytoplasmic ratio bare nuclei, which were round to oval in shape. Homer wright rosette arrangement was formed by tumor cells that were radially arranged in a circle. The neuropil, which was stained as eosinophilic material was seen in the center of rosette arrangement. Conclusions: Hence on the basis of age and rare cutaneous presentation along with cytological findings; clinical features and radiological findings we can provide a diagnosis of metastasis neuroblastoma.