Cutaneous Mucormycosis

Roberts, H. J.

doi:10.1001/archinte.1962.03620190110017

Cited by 25 publications

(1 citation statement)

References 10 publications

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“…This infection is ,histologically characterized by broad nonseptate hyphae invasion of the blood vessels and their walls, resulting in vascular thrombosis and tissue necrosis [3-51. The different forms of mucormycosis are categorized by the anatomic area involved: rhinocerebral [6,7J, pulmonary [8,9], gastrointestinal [10,11], cardiac [k2], renal [13,14], primary cutaneous [15][16][17] and disseminated.…”

Section: Introductionmentioning

confidence: 99%

Primary cutaneous mucormycosis: a diagnosis to consider

García‐Bustínduy

Guimerá‐Martín‐Neda

Noda

et al. 1999

Acad Dermatol Venereol

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Primary cutaneous mucormycosis is a deep fungal infection, mainly seen in diabetics and immunocompromised subjects. Rapid diagnosis and therapy are necessary to avoid fatal outcome. We describe the complete histopathological and microbiological studies of primary cutaneous mucormycosis in a 74-year-old man with several risk factors, such as chronic obstructive pulmonary disease, respiratory acidosis, hemolytic anemia, myelodysplastic syndrome and iatrogenic diabetes, due to corticosteroid therapy. He developed two cutaneous necrotic scars on his left leg. Mucormycosis was suspected and specimens from surgical débridement were histopathologically and microbiologically studied confirming the clinical diagnosis. Amphotericin B was given topically and intravenously resulting in complete healing of the ulcer. Risk factors and microbiological studies are compared with those in the current literature. It is necessary in certain cases to suspect mucormycosis infections in diabetics, immunocompromised subjects and even in healthy individuals. Rapid diagnosis and treatment are important, but they should be based on complete histopathological and microbiological studies, to establish the genus of the causal agent.

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