Cutaneous manifestations of liver diseases

Ghosn, Samer; Kibbi, Abdul‐Ghani

doi:10.1016/j.clindermatol.2008.02.001

Cited by 37 publications

(31 citation statements)

References 60 publications

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“…Outras lesões vasculares já descritas incluem: unhas de Terry, manchas de Bier, hemangioma arteriovenoso, flushing, fácies pletórica, telangiectasias nevoides unilaterais e caput medusae. Os pacientes podem também apresentar lesões purpúricas, epistaxes e hemorragia gengival devido à fragilidade vascular e deficiência de fatores de coagulação 8,13 . O prurido foi um achado comum, presente em 17,2% dos pacientes hepatopatas e manifesta-se tipicamente por sensação de coceira em palma das mãos e planta dos pés, embora o prurido difuso seja comum e escoriações possam ser evidentes.…”

Section: Materiais E Métodosunclassified

“…O tratamento desta condição é bastante difícil, e uma resina ligadora de ácidos biliares (colestiramina) é a terapia de primeira linha. Outros tratamentos incluem inibidores da recaptação de serotonina, plasmaférese e antagonistas opioides 8,34 .…”

Section: Materiais E Métodosunclassified

“…Muitos tipos de interações entre estes dois órgãos são encontrados: a doença no fígado pode causar lesões de pele; a pele e o fígado podem estar envolvidos no mesmo processo patogênico (tais como vistos na doença dos histiócitos, hemangiomas, sarcoidose, deficiência de α1-antitripsina, hemocromatose); doenças de pele podem levar a alterações hepáticas (tais como implantes secundários de tumores malignos de pele); e o fígado pode ser lesado por drogas do tratamento de doenças de pele (e.g., metotrexato na terapia da psoríase) ou vice-versa (e.g., interferon [IFN] para o tratamento na infecção pelo vírus C) 8 .…”

Section: Introductionunclassified

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Manifestações dermatológicas em uma casuística de doença hepática crônica de um hospital de referência em Belém, Estado do Pará, Brasil

Maia¹,

Araújo

Pires

et al. 2014

Rev Pan-Amaz Saude

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Section: Materiais E Métodosunclassified

Section: Introductionunclassified

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Manifestações dermatológicas em uma casuística de doença hepática crônica de um hospital de referência em Belém, Estado do Pará, Brasil

Maia¹,

Araújo

Pires

et al. 2014

Rev Pan-Amaz Saude

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“…Hautveränderungen bei Leberkrankheiten sind zahlreich, jedoch meist unspezifisch [2,10,14]. Am häufigsten sind sie im Rahmen einer chronisch aktiven Hepatitis oder im Rahmen einer äthylisch bedingten Lebererkrankung vorhanden.…”

Section: Hautveränderungen Bei Leberkrankheitenunclassified

Hautveränderungen bei internistischen Krankheiten

Lautenschlager

2008

Internist

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Many aspects of cutaneous signs are of importance to nondermatologists, as skin manifestations can reflect internal disease states, either directly or as a result of a complication or treatment and therefore can lead to the diagnosis of systemic illness. Serious morbidity and mortality can be avoided by early recognition of only minor cutaneous manifestations signaling internal problems. Limited forms of collagen vascular disease exemplify the important marker function of the skin for diagnosis as well as for prognosis with their typically favorable course permitting a less aggressive treatment. The utmost important prerequisite of diagnosing skin conditions is an accurate and thorough examination of the skin, the adjacent mucous membranes and the integumentary appendages. In a first step, the primary site of the cutaneous condition should be identified (e.g. epidermal, dermal or subdermal) and then the form, the pattern, and distribution should be recognized. There are many comprehensive and excellent textbooks available for guidance. This article focuses on the more common dermatologic conditions linked to different organ systems involved (excluding infectious diseases, metabolic diseases and drug induced conditions).

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“…Alcohol was shown to increase the activity of earlier enzymes in this pathway, which leads to further accumulation of porphyrins and worsens the condition in patients with preexisting PCT. Agents or conditions that adversely affect the liver, such as alcohol abuse and/or hepatitis C, can lead to acquired PCT [97]. Newonset PCT in patients with other stigmata of alcoholic liver disease should alert clinicians of possible alcohol abuse.…”

Section: Alcoholmentioning

confidence: 99%

Dermatologic Signs and Symptoms of Substance Abuse

Raiker¹,

Aouthmany²

2016

J Clin Exp Dermatol Res

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Various substances of abuse are known to cause specific cutaneous manifestations. In this review, we highlight the cutaneous manifestations associated with the use of cocaine, heroin, marijuana, methamphetamine, alcohol, and anabolic steroids. Cutaneous signs of tanning addiction are also discussed, as tanning bed use is a particularly relevant and growing problem in Dermatology. We also provide examples of general signs of drug abuse, including stigmata of injection drug use, vascular complications, and infectious complications. This review aims to make clinicians more aware of these signs in order to better recognize substance abuse disorders and guide effective treatment.

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Cutaneous manifestations of liver diseases

Cited by 37 publications

References 60 publications

Manifestações dermatológicas em uma casuística de doença hepática crônica de um hospital de referência em Belém, Estado do Pará, Brasil

Manifestações dermatológicas em uma casuística de doença hepática crônica de um hospital de referência em Belém, Estado do Pará, Brasil

Hautveränderungen bei internistischen Krankheiten

Dermatologic Signs and Symptoms of Substance Abuse

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