Cutaneous manifestations of breast carcinoma

Giorgi, Vincenzo De; Grazzini, Marta; Alfaioli, Barbara; Savarese, Imma; Corciova, Suzana Alexandra; Guerriero, Giuseppe; Lotti, Torello

doi:10.1111/j.1529-8019.2010.01365.x

Cited by 101 publications

(170 citation statements)

References 83 publications

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“…Breast cancer in women metastasizes to the skin frequently and cutaneous metastasis is observed in 23.9% of patients (1,6). Although it it (cutaneous metastasis) is generally detected in patients diagnosed with breast cancer, it can be also observed as the primary finding of the malignity (6).…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Zosteriform Cutaneous Metastasis from Breast Cancer

Demir¹,

Salaeva²,

Altunay³

et al. 2017

Haseki

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Breast cancer is the most common cancer among women and the second leading cause of cancer deaths, after lung cancer. Cutaneous breast cancer metastases often develop as direct involvement and local spread and often manifest as solid painless nodules in the anterior chest wall. Internal malignant skin metastases rarely present like soft nodules, telangiectasia-like lesions, neoplastic alopecia, erysipeloides carcinoma, erythema annulare-like, herpetiformis or zosteriform, targetlike, pyodermic and morphea-like lesions. In this article, we present a 49-year-old female patient describing a sensation of burning pain with erythematous papules and plaques in a zosteriform distribution. The diagnosis of zosteriform cutaneous metastases from a breast cancer was made. Majority of these cases may be misdiagnosed as herpes zoster infection and can be treated with antiviral drugs. Therefore, cutaneous metastases should be kept in mind in the differential diagnosis of lesions in zosteriform distribution. Keywords: Cutaneous metastasis, zosteriform cutaneous metastasis, breast cancerMeme kanseri kadınlar arasında en sık görülen kanserdir ve akciğer kanserinden sonra, kansere bağlı ölümlerin en sık sebebidir. Meme kanserinin deri metastazı genellikle direkt invazyon ve lokal yayılma şeklinde gelişir ve sıklıkla göğüs ön duvarında solid ve ağrısız nodüller şeklinde ortaya çıkar. İnternal malignitelerin deri metastazları nadiren yumuşak nodüller, telenjiektazi benzeri lezyonlar, neoplastik alopesi, karsinoma erizipeloides, eritema anüler benzeri, herpetiform veya zosteriform, target benzeri, piyodermatik ve morfea benzeri lezyonlar ile prezente olabilmektedir. Bu makalede zosteriform dizilimli, deriden kabarık, eritematöz papül ve plaklarla polikliniğimize başvuran, lezyonlarında yanma tarifleyen, bilateral mastektomi, kemoterapi ve radyoterapi öyküsü olan 49 yaşında bir kadın hasta, deri metastazların nadir görülen zosteriform dağılımına dikkat çekmek ve herpes zoster enfeksiyonlarının ayırıcı tanısında deri metastazlarını hatırlatmak amacıyla sunulmaktadır.AnahtarSözcükler: Deri metastazı, zosteriform deri metastazı, meme kanseri

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Section: Discussionmentioning

confidence: 99%

A Rare Case of Zosteriform Cutaneous Metastasis from Breast Cancer

Demir¹,

Salaeva²,

Altunay³

et al. 2017

Haseki

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“…Kutanöz metastatik lezyonların; erizipeloid, telenjiektatik, alopesi neoplastika, jeneralize eritematöz yamalar, eritema anüler sentrifigum, zosteriform ve targetoid olmak üzere diğer kötü prognozlu tipleri de rapor edilmiştir. 2,3,6,10,11 Olgumuzda sırt bölgesinde daha belirgin olmak üzere gövdede yaygın yerleşimli, Darier bulgusunun pozitif olduğu, asemptomatik, mastositoz benzeri plaklarla karakterize metastatik deri lezyonları mevcuttu (Resim 1).…”

Section: Mastositoz Benzeri Deri Lezyonları Tanı Konulmamış Meme Kansunclassified

“…2 Ayrıca, meme karsinomu kaynaklı deri metastazlarının %80'inden fazlasında östrojen reseptör pozitifliği gösterilmiştir. 12 Olgumuzda da meme karsinomu metastazı ile uyumlu olarak dermiste yerleşmiş neoplastik hücrelerde immünkimyasal olarak östrojen reseptör pozitifliği saptanmıştır (Resim 3).…”

Section: Mastositoz Benzeri Deri Lezyonları Tanı Konulmamış Meme Kansunclassified

May Mastocytosis Like Skin Lesions, be the First Manifestation of Undiagnosed Breast Cancer?: Case Report

Erturan¹,

Ceyhan²,

Mullaaziz³

et al. 2017

Turkiye Klinikleri J Dermatol

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eri metastazı malignitelerin geç dönem bulgusudur ve sıklıkla kötü prognozun göstergesidir. Çeşitli kanser türlerinde kutanöz metastaz oranı %0,7-10,4 arasında rapor edilmiş olup, nadiren de olsa iç organ malignitelerinin ilk habercisi olabilmektedir. Primer internal malignitesi olup henüz tanı almamış hastalarda, metastatik deri lezyonlarının tanınıp diğer dermatolojik lezyonlardan ayırt edilmesi önem taşımaktadır. Deriye metastaz yapan tümörler açısından incelendiğinde, malign melanom sınıflama dışında bırakıldığında, deride en sık (%23,9) metastazı saptanan solid organ tümörü meme karsinomudur.

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“…In this context, the incidence of cutaneous presentations of breast cancer in patients showing this kind of neoplasia reaches 23.9% [2] . Among the several clinical cutaneous presentations of metastatic breast cancer, neoplastic alopecia appears as an unusual pattern of this metastasis, where neoplastic cells invade the dermis of the scalp and cause either direct or indirect damages to the pilosebaceous unit [5] .…”

Section: Introductionmentioning

confidence: 99%

Alopecia neoplastica: An uncommon presentation of metastatic breast carcinoma

Oliveira¹,

Silveira²,

Moraes

et al. 2016

J Surg Dermatol

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Cutaneous metastasis may correspond to the initial clinical presentation of hidden internal malignancies. In patients presenting said neoplasia, clinical manifestations of breast cancer reaches 23.9%. Considering that neoplastic alopecia appears as an unusual pattern of the said metastasis, this report describes a case of such uncommon neoplastic alopecia which presents itself as a cutaneous metastasis of rapid progression in a patient with prior breast cancer history. We present a 47-year-old female patient reporting lesions at the scalp, and who was asymptomatic with a one-year evolution. The patient reported prior breast cancer history and presence of lung metastasis, and was undergoing chemotherapy at the time of consultation. A dermatological evaluation showed only a nodular lesion with erythematous surface and a diameter measuring about 4 cm, firm in consistency, and immovable. She was routed to the Department of Dermatological Surgery, and the results from histopathology were consistent with a diagnosis of metastatic breast adenocarcinoma. Neoplastic alopecia appears as an unusual form of cutaneous metastasis which is predominantly described in association with breast cancer. The lesion's clinical features play a crucial role at the differential diagnosis, as the presence of erythema could distinguish neoplastic alopecia from alopecia areata. The existence of cutaneous metastasis leads to unfavorable outcomes. As a conclusion, cutaneous evaluation of patients is essential for treating visceral metastases, since the forms of cutaneous metastasis are diverse and can also affect the scalp.Keywords: Alopecia; breast cancer; metastasis; skin cancer Citation: de Oliveira FL, de Barros Silveira LKC, Moraes TS, Craide FH, Briceño MCM, et al. Alopecia neoplastica: An uncommon presentation of metastatic breast carcinoma.

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Cutaneous manifestations of breast carcinoma

Cited by 101 publications

References 83 publications

A Rare Case of Zosteriform Cutaneous Metastasis from Breast Cancer

A Rare Case of Zosteriform Cutaneous Metastasis from Breast Cancer

May Mastocytosis Like Skin Lesions, be the First Manifestation of Undiagnosed Breast Cancer?: Case Report

Alopecia neoplastica: An uncommon presentation of metastatic breast carcinoma

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