Cutaneous lymphangitis carcinomatosa in a patient with lung adenocarcinoma: Case report and literature review

Prat, L.; Chouaïd, C.; Kettaneh, A.; Fardet, L.

doi:10.1016/j.lungcan.2012.09.009

Cited by 16 publications

(29 citation statements)

References 17 publications

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“…There are few published cases of cutaneous lymphangitis carcinomatosa and, to our knowledge, this is the first case of cutaneous lymphangitis carcinomatosa associated with paraneoplastic DM 11 – 13…”

Section: Discussionmentioning

confidence: 81%

Rapidly lethal dermatomyositis associated with cutaneous lymphangitis carcinomatosa

et al. 2013

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SUMMARYA 70-year-old woman with a recent diagnosis of dermatomyositis (DM) presented to the dermatology department for study of a probably paraneoplastic syndrome. On examination, we observed discrete, indurated, reddish, painful plaques and nodules on her abdomen and both thighs. A cutaneous biopsy from an abdominal nodule, performed as part of the paraneoplastic workup, was suggestive of cutaneous lymphangitis carcinomatosa, secondary to unknown malignancy. An extensive investigation to locate the site of the primary tumour revealed no specific findings. A course of palliative chemotherapy with cisplatin and 5-fluorouracil was then given, but the patient's condition deteriorated and 6 months after her initial observation the patient died. We describe this case because, to our knowledge, the association between DM and cutaneous lymphangitis carcinomatosa has not been described yet in the literature and to highlight that, DM can be a rapidly lethal disease. BACKGROUND

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Section: Discussionmentioning

confidence: 81%

Rapidly lethal dermatomyositis associated with cutaneous lymphangitis carcinomatosa

et al. 2013

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“…Although little data exist on the prevalence of other subtypes, smaller case reports of cutaneous metastases from lung cancer include descriptions of telangiectatic, erysipelas-like, and zosteriform patterns. Carcinoma erysipeloides secondary to lung cancer is rarely described, with our search finding only 7 prior case reports 7, 8, 9. In women, skin metastases are overwhelmingly related to breast cancer followed by ovarian and oral cavity cancers 4 .…”

Section: Discussionmentioning

confidence: 95%

Rare presentation of cutaneous lung cancer metastasis presenting as carcinoma erysipeloides

et al. 2019

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“… 2 7 The most common histological feature observed in patients with lung cancer who develop CLC is adenocarcinoma, as in the present case. 8 Cutaneous metastasis in lung cancer tends to occur in order in the anterior chest wall, back and abdomen. 7 9–11 Cutaneous metastases are considered a late event in the evolution of the majority of malignancies.…”

Section: Discussionmentioning

confidence: 99%

“… 3 7 12 The only known treatment for CLC is systemic chemotherapy, but early diagnosis can lead to earlier anticancer treatment. 8 Osimertinib may improve the prognosis of the patients harbouring the EGFR T790M mutation; however, osimertinib was not available for treatment at the time of this diagnosis. 13–15 Supportive care for lymphoedema due to CLC, as follows, can improve patients’ quality of life and may even influence the progression of the disease: manual lymph drainage, compression therapy with bandages or special stockings, dermatological skin care and psychological treatment.…”

Section: Discussionmentioning

confidence: 99%

Cutaneous lymphangitis carcinomatosa made cervicofacial oedema intractable in a patient with superior vena cava syndrome

et al. 2018

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Cutaneous lymphangitis carcinomatosa (CLC) is a rare form of cutaneous metastasis that causes lymphoedema and various eruptions. We report a case of lung cancer with CLC that caused both superior vena cava (SVC) stenosis and cervicofacial oedema, suggestive of SVC syndrome. A 64-year-old woman with lung adenocarcinoma presented with cervicofacial oedema and erythema, followed by severe dyspnoea 2 months after four cycles of carboplatin, pemetrexed and bevacizumab triplet therapy. Although chest CT indicated SVC stenosis, cervicofacial oedema remained despite treating the SVC stenosis via balloon dilation. A skin biopsy of the erythematic sample confirmed CLC as the cause of the patient’s symptoms. CLC should be considered as a differential diagnosis of cervicofacial oedema in addition to SVC syndrome, especially when it is observed in combination with skin erythema and induration. Moreover, a skin biopsy should be performed promptly for accurate diagnosis of CLC and to decide on appropriate treatment.

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Cutaneous lymphangitis carcinomatosa in a patient with lung adenocarcinoma: Case report and literature review

Cited by 16 publications

References 17 publications

Rapidly lethal dermatomyositis associated with cutaneous lymphangitis carcinomatosa

Rapidly lethal dermatomyositis associated with cutaneous lymphangitis carcinomatosa

Rare presentation of cutaneous lung cancer metastasis presenting as carcinoma erysipeloides

Cutaneous lymphangitis carcinomatosa made cervicofacial oedema intractable in a patient with superior vena cava syndrome

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