Cutaneous lymphangiectasia of the vulva secondary to tuberculosis

Abstract

Cutaneous lymphangiectasia, also called as acquired lymphangioma, is a benign cutaneous disorder involving the dermal and subcutaneous lymphatic channels. It can rarely occur on the vulva. We describe a 35-year-old woman who came with multiple raised lesions over the vulva and left upper thigh of 1 year duration. She gave history of getting treated for multiple swellings that developed over right side of the neck and inguinal regions on both sides three decades ago. On local genital examination, the patient had a large polypoidal growth involving both sides of the vulva, left upper thigh, and over pubic area. Multiple linear scars were present over the upper thighs and groin bilaterally. The patient underwent simple vulvectomy and left thigh growth excision. Histopathological examination of the vulvectomy specimen confirmed our diagnosis.

Vulval Tuberculosis: The Histomorphological Spectrum in Patients with HIV Co-Infection and AIDS

“…Esthiomene, woody vulva, elephantiasis, cutaneous lymphangiectasia and lymphangioma circumscriptum have been recognized sequelae of such lymphatic obstruction, that may be associated with active inguinal tuberculous lymphadenitis [10,36,38,41,53]. Biopsies of 3 patients with clinically edematous vulval lesions and inguinal lymphadenopathy in the present study demonstrated the common finding of prominent dilated lymphatic and blood vessels ( Figures 6B and 6C).…”

“…In the last 40 years, additional descriptive terms have been employed, including nodules, ulcers, abscesses, papules, papulonecrotic discrete lesions or vulval hypertrophy and edema. To date, most of the described vulval histomorphology has focused on classic TB or tuberculous hypersensitivity responses [36][37][38][39][40][41][42][43][44][45][46].…”

Lymphovenous Anastomosis and Secondary Resection for Noonan Syndrome with Vulvar Lymphangiectasia

“…7 Histologically, dilated lymphatic channels are present in the superficial and mid-dermis; few dilated lymphatics are seen in the deep dermis. 8 As the lesions progress, functional impairment regarding urination and sexual intercourse can develop, in addition to cosmetic problems. However, the treatment of lymphangiectasia can be very challenging because of high recurrence rate after surgery, which is reported to be 23.1%.…”

“…3,9 The prognosis for patients with diffuse lymphangiomatosis is poor if the condition is resistant to standard therapies. 8 More conservative treatments such as skin care compression are difficult to apply considering the location of the lesions. 10 Carbon dioxide lasers causing superficial vaporization of the lesions have been also described in the treatment.…”

A Rare Case of Pregnancy Induced Lymphangioma of Vulva in A Primigravida with Singleton Pregnancy

“…Differential diagnoses of ALV include primary LC of vulva, genital warts, herpes zoster, molluscum contagiosum, syringoma, leiomyoma, cellular angiofibroma, haemangioendothelioma, angiomyofibroblastoma, and aggressive angiomyxoma. [11][12][13] Histopathologic confirmation of the clinical diagnosis may be done to avoid misdiagnosis and wrong treatment.…”