Cutaneous Involvement in a High Grade B-Cell Lymphoma With Rearrangement of MYC, BCL2, and BCL6 Transformed From Follicular Lymphoma

Histologic transformation of follicular lymphoma: pathologists’ viewpoint

“…Transformation to high-grade B-cell lymphoma (HGBL) with MYC and BCL2 and/or BCL6 rearrangements (i.e., double-hit lymphoma, HGBL-DH) or HGBL, not otherwise specified; [6][7][8][9][10] classic Hodgkin lymphoma (CHL); [11][12][13][14][15] B-lymphoblastic leukemia/lymphoma (B-ALL); [16][17][18][19] B-prolymphocytic leukemia; 20 plasmablastic lymphoma; [21][22][23][24] anaplastic large-cell lymphoma-like lymphoma; [25][26][27] and histiocytic/dendritic cell (H/ DC) sarcoma 28,29 is also rarely observed. This review focused on the histopathologic variety and proposal of definition of HT.…”