Cutaneous Crohn's disease successfully treated with adalimumab

Stingeni, Luca; Neve, Diletta; Bassotti, Gabrio; Simonetti, S.; Bianchi, Leonardo; Hansel, Katharina

doi:10.1111/jdv.13315

Cited by 6 publications

(3 citation statements)

References 10 publications

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“…By the period of three months, signs of clinical improvement were noted. In light of the literature, adalimumab has been reported to work effectively for MCD patients [ 14 - 17 ]. In one case of cutaneous CD, significant improvement of skin lesions was observed after starting adalimumab 160 mg, 80 mg after two weeks, and 40 mg every other week.…”

Section: Discussionmentioning

confidence: 99%

“…In one case of cutaneous CD, significant improvement of skin lesions was observed after starting adalimumab 160 mg, 80 mg after two weeks, and 40 mg every other week. Remission was obtained after four months [ 14 ]. A similar situation was reported previously, which utilized the dosage of adalimumab for CD, with 160 mg administered as four injections over the first two days, 80 mg on day 15, and then 40 mg every other week following that.…”

Section: Discussionmentioning

confidence: 99%

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Metastatic Crohn’s Disease in External Genitalia With Good Outcome on Adalimumab: A Rare Case of a Saudi Female and a Short Review

Alotaibi,

Fathaddin,

AlMutairi

et al. 2023

Cureus

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Crohn’s disease (CD), an inflammatory bowel disease that involves the gastrointestinal tract, is observed in daily hospital practice. On the other hand, metastatic Crohn's disease (MCD) is a rare entity in which cutaneous lesions are found in regions apart from the digestive system. This article describes a rare case of cutaneous CD in a Saudi female, which manifested initially as vulvar and perianal skin lesions. The diagnosis was proven by skin biopsy, and adalimumab offered effective treatment. Although cutaneous MCD is rare, it is an important cutaneous manifestation, as early detection creates the possibility of accessing effective management.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Metastatic Crohn’s Disease in External Genitalia With Good Outcome on Adalimumab: A Rare Case of a Saudi Female and a Short Review

Alotaibi,

Fathaddin,

AlMutairi

et al. 2023

Cureus

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“…Cury, et al presentaron el caso de un hombre con enfermedad de Crohn colónica y lesiones acneiformes diagnosticadas como ECC en el tronco, que remitieron por completo luego del tratamiento con adalimumab 12 . Asimismo, Stingeni, et al informaron el caso de un paciente sin enfermedad intestinal y con lesiones de ECC nodulares-ulcerativas en glúteos, que se resolvieron con este fármaco anti-TNF 13 . Por el contrario, el paciente comunicado desarrolló ECC a pesar de la enfermedad intestinal estable en tratamiento con adalimumab.…”

Section: Discussionunclassified

Enfermedad de Crohn cutánea en un adulto con enfermedad intestinal estable en tratamiento con adalimumab

Miranda¹,

Elías²,

Herrero³

et al. 2021

MCUT

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afección en la piel. Caso clínico: Varón de 43 años de edad que presentaba una úlcera en el glúteo izquierdo, asintomática, de cuatro meses de evolución. Tenía como antecedente enfermedad de Crohn ileal de fenotipo estenosante, tratado con adalimumab desde dos años antes, sin actividad al momento de la consulta. La histopatología reveló granulomas confluentes sin caseosis central. Las técnicas de Ziehl Neelsen y PAS resultaron negativas. No hubo desarrollo de bacterias, micobacterias u hongos en los cultivos. Con el antecedente de enfermedad inflamatoria intestinal, la clínica y los estudios complementarios se confirmó el diagnóstico de enfermedad de Crohn cutánea. Conclusión: Se comunica un caso infrecuente de enfermedad de Crohn cutánea, debido a su aparición en un paciente con enfermedad de Crohn intestinal estable tratado con adalimumab. Además, debido a la presentación clínica inicial en forma de pústula y su posterior evolución a úlcera, es importante distinguirlo del pioderma gangrenoso.

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Miscellaneous Uses of Biologic and Systemic Agents in Other Dermatologic Conditions

Kimmel

Nia

Hashim

et al. 2017

Biologic and Systemic Agents in Dermatology

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Cutaneous Crohn's disease successfully treated with adalimumab

Cited by 6 publications

References 10 publications

Metastatic Crohn’s Disease in External Genitalia With Good Outcome on Adalimumab: A Rare Case of a Saudi Female and a Short Review

Metastatic Crohn’s Disease in External Genitalia With Good Outcome on Adalimumab: A Rare Case of a Saudi Female and a Short Review

Enfermedad de Crohn cutánea en un adulto con enfermedad intestinal estable en tratamiento con adalimumab

Miscellaneous Uses of Biologic and Systemic Agents in Other Dermatologic Conditions

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