Cutaneous Complications of Injection Drug Abuse

Kanish, Bimal; Bhatia, Anuradha; Goyal, Sandeep

doi:10.14260/jemds/2014/2967

Cited by 3 publications

(6 citation statements)

References 64 publications

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“…[20] IDU is associated with various vasculitic and vasculopathic processes including urticarial vasculitis, Churg–Strauss vasculitis, Raynaud phenomenon, Henoch–Schonlein purpura, necrotizing vasculitis, Buerger's disease and pseudovasculitis, acute generalized exanthematous pustulosis, and Steven Johnson's syndrome. [30]…”

Section: Discussionmentioning

confidence: 99%

Local complications of pentazocine abuse: Case report and review

Kumar¹,

Soren

Simlai

et al. 2018

Ind Psychiatry J

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The skin is the tissue most commonly affected by intravenous drug addiction with pentazocine. The present article attempts to review the adverse effects of injecting drug use along with one case report of cutaneous complications of injection pentazocine abuse underlining the need for early identification, management, and above all prevention. It also provides credence to the fact that pentazocine abuse is common in paramedical staff, and easy accessibility of pentazocine injection can easily lead to serious complications.

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Section: Discussionmentioning

confidence: 99%

Local complications of pentazocine abuse: Case report and review

Kumar¹,

Soren

Simlai

et al. 2018

Ind Psychiatry J

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“…20 Vasculitis associated with cocaine reported in various studies are; urticarial vasculitis, retiform purpura, Henoch Schonlein purpura, Raynaud's phenomenon and Churg-Strauss Vasculitis. 10,17,20,21,22 Urticaria is a common skin manifestation observed in heroin addicts in the past studies. It results from mast cell degranulation and mast cell release.…”

Section: Table-iv Distribution Of Patient According To Mode Of Drug Intakementioning

confidence: 99%

“…Skin and soft tissue infections are the most common acute changes observed in drug abusers and considered to be main cause of admission among intravenous drug addicts. 10 Abscesses and cellulitis the most frequently noted skin and soft tissue infections in drug addicts. Skin pop induces trauma to skin and underlying soft tissue and use of unsterilized needles may help the pathogens like bacteria to enter the human body through skin resulting into cellulitis.…”

Section: Table-iv Distribution Of Patient According To Mode Of Drug Intakementioning

confidence: 99%

“…26 Generalized hyperpigmentation of body and at the site of injection has been noted in the literature. 10 Oral mucosal changes are reported with different modes of drug administration; sniffing, ingesting with food, mucosal application, inhalation and intravenous injection. 27 Drugs including opiates, amphetamines, miscellaneous hallucinogens, marijuana, and alcohol may produce xerostomia and other changes on lips.…”

Section: Table-iv Distribution Of Patient According To Mode Of Drug Intakementioning

confidence: 99%

“…It had been observed in the previous studies that majority of patients seeking treatment in medical clinic for drug addictions had skin manifestations due to drug abuse. 10 The rationale of carrying out this study was to identify cutaneous findings related to drug abuse especially in chronic skin lesions which may have severe implications on human body if not treated timely.…”

Section: Introductionmentioning

confidence: 99%

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Frequency of cutaneous manifestations in drug abuse patients.

Rafiq¹,

Mehdi²,

Shafi³

2021

TPMJ

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Objective: Drug abuse and drug addiction cases have been increased immensely in last few decades in Pakistan. This study was conducted to assess the frequency of cutaneous manifestations in drug abuse patients. Study Design: Cross Sectional study. Settings: Dermatology Department of a DHQ Teaching Hospital/Sahiwal Medical College, Sahiwal and Central Jail Hospital, Sahiwal. Period: November 2019 to June 2020. Material & Methods: 50 patients with drug abuse irrespective of age and gender were selected. Skin manifestations based on history and examination recorded on predesigned proforma. Laboratory investigations and skin biopsies were performed to confirm diagnoses in doubtful cases. Results: A total of 50 male patients with age above 16 years were enrolled. Single drug addiction was noticed in 62% (n=31) and polydrug abuse was observed in 38% (n=19). Regarding mode of drug intake, single and multiple modes of drug administration were seen in equal number 50% (n=25) each. Major bulk of skin manifestations were chronic including skin scars 66% (n=33), xerosis 60% (n=30), hyperpigmentation 58% (n=29), oral mucosal changes 94% (n=47) and facial skin changes 60% (n=30). Acute along with chronic skin changes were observed in 30% (n=15) mainly including injection marks 30% (n=15), vascular changes 12% (n=6) and infections 8% (n=4). Conclusion: Skin scars, xerosis, hyperpigmentation and oral mucosal changes are the common skin changes observed among drug abusers. Thus, physicians need to be aware of skin signs of drug abuse for timely recognition of substance abuse disorders and effective management.

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The Experrience of Successful Treatment of Phegmonous Lesion of the Patient With Parenteral Drug Addiction

Bekbaev

Melnikov

Topchiev

et al. 2022

Tavricheskiy Mediko-Biologicheskiy Vestnik

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The case of development of the vast purulent necrotic lesion of the left upper limb complicated by the development of sepsis appeared after the parenteral introduction of synthetic drug surrogate («speed»). The peculiarities of the disease course, surgical and complex treatment are described in details. The clinical case is interesting because on the background of chronic alcoholism, the injection of synthetic drug surrogate was complicated by the development of phlegmon of the back surface of the left hand and the generalization of infection in the form of purulent necrotic damage of the upper limb, sepsis. The use of oxygenated water «OxyEnergy» in the complex treatment in its pure form (per os, 30 ml 2 times a day) and in dressings with the «Levomekol» ointment in combination with NO-therapy allowed to obtain a good clinical result.

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Cutaneous Complications of Injection Drug Abuse

Cited by 3 publications

References 64 publications

Local complications of pentazocine abuse: Case report and review

Local complications of pentazocine abuse: Case report and review

Frequency of cutaneous manifestations in drug abuse patients.

The Experrience of Successful Treatment of Phegmonous Lesion of the Patient With Parenteral Drug Addiction

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