Customised design of a patient specific 3D printed whole mandible implant

Abstract

<p>In this study we investigate the design methodology for the creation of a patient specific, whole mandible implant based on a patient’s medical imaging data. We tailor the implant as a treatment option for a patient who will undergo a mandibulectomy due to cancer infiltration of the jaw. We create a 3D representative model of the patient’s skeletal structure from CT scan data, and us this to generate the implant from the patient’s corrupt mandible. In this particular case study the cancer is restricted to the right region of the mandible, and so the left side is used in a symmetry matching approach to create the final model for manufacturing. The final design was 3D printed in medical grade titanium and finished using a mechanical polishing technique, the yield a near mirror finish. We found the final implant to be highly robust, and an excellent fit to a representative model of the patient’s skeletal anatomy. We believe this approach to hold considerable potential for implementation as a treatment option for mandibular complications. </p>

Patient-Specific Surgical Implants Made of 3D Printed PEEK: Material, Technology, and Scope of Surgical Application

“…Reconstructive surgeries can be extremely challenging even to the most experienced surgeon especially due to complex anatomy, sensitivity of the involved systems, and uniqueness of each defect [ 1 ]. The need to reconstruct the defect in the best possible way along with time minimization for the surgical procedure is of crucial importance to surgeons for improving patient outcomes and well-being [ 2 ]. Patient-specific implant (PSI) can be an effective solution in this situation designed to fit precisely in the anatomical defects or malformations.…”

“…Recently, the US Food and Drug Administration (FDA) increased their approval of 3D printed implants under the 510k (premarket notification) approval system. This will allow the healthcare providers to use the parts manufactured by AM in routine and for complex surgical procedures [ 2 , 9 ].…”

Evaluation of Dimensional Accuracy of 3D printed mandibular model using two different Additive Manufacturing Techniques based on Ultra-Low Dose Multislice Computed Tomography scan data

“…This goal has led to considerable research interest in the area of patient specific technologies. Modern design techniques and additive manufacturing are beginning of positively impact areas of pre-operative planning (Mohammed et al, 2017) 3D printing involves creating a real-world physical 3D model from a computer model. When printing from computed tomography (CT) data, CT slices can be printed sequentially as two-dimensional (2D) layers, and these can be arranged to create the 3D model.…”

Biomechanical Assessment of Design Parameters on a Self-Developed 3D-Printed Titanium-Alloy Reconstruction/Prosthetic Implant for Mandibular Segmental Osteotomy Defect

“…Ti powders were heated using lasers and then fused layer by layer until a complete 3D-printed Ti mandibular implant was produced. The product implants were later implanted onto the craniofacial bone of an 83-year-old woman [7,8]. This successful clinical application of 3D metal printing has garnered considerable interest.…”

“…This successful clinical application of 3D metal printing has garnered considerable interest. Subsequently, many studies have been conducted involving 3D-printed Ti mandibles, including studies on the manufacturing process and clinical evaluation [8][9][10][11], an in vivo experiment [12], an animal experiment [13], and finite element (FE) analyses [10,14,15]. Adopting 3D printing could provide many exciting possibilities for the medical industry, including customized or patient-matched 3D-printed implants.…”