Current trends in the analysis and quality control of food supplements based on plant extracts

Fibigr, Jakub; Šatı́nský, Dalibor; Solich, Petr

doi:10.1016/j.aca.2018.08.017

Cited by 86 publications

(79 citation statements)

References 70 publications

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“…In Italy, more than 20% of the Italian population is considered “regular” consumer of these herbal products, as highlighted from the recent European PlantLibra (Plant Food Supplements: Levels of Intake, Benefit and Risk Assessment) consumer survey [ 5 ]. The wide range of herbal food supplements on the market and the non-attendance of effective legislation to guarantee the safety and quality aspects make these products vulnerable for fraud, falsification and adulteration [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

“…Although gemmotherapy has been used since ancient times because of the peculiar content of buds in bio-active compounds, especially polyphenols, nowadays BDs are still a little studied “niche” production [ 18 , 19 ]. The lack of detailed scientific information and a clear and unique regulation, as well as for the category of herbal food supplements in overall [ 6 , 7 , 20 ], it makes these products high risk and there is an increase request for efficient quality control to ensure the proper identification of the botanical source and their content [ 21 ].…”

Section: Introductionmentioning

confidence: 99%

“…A strategy based on the untargeted UV-Visible fingerprinting coupled to chemometrics (Principal Component Analysis—PCA) has been proposed for the screening of the polyphenolic BDs profile in order to obtain a rapid control tool [ 43 ]. Finally, HPLC methods were used to obtain a targeted chromatographic profile [ 7 , 44 ] of the main polyphenol classes (i.e., flavonols, benzoic acids, catechins, cinnamic acids). Polyphenols are correlated with their potential health-promoting activity [ 45 ], even if they are strongly influenced both by the methods and protocols used [ 35 ].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Bud-Derivatives, a Novel Source of Polyphenols and How Different Extraction Processes Affect Their Composition

Turrini

Donno

Beccaro

et al. 2020

Foods

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The use of herbal food supplements, as a concentrate form of vegetable extracts, increased so much over the past years to count them among the relevant sources of dietetic polyphenols. Bud-derivatives are a category of botanicals perceived as a “new entry” in this sector since they are still poorly studied. Due to the lack of a manufacturing process specification, very different products can be found on the market in terms of their polyphenolic profile depending on the experimental conditions of manufacturing. In this research two different manufacturing processes, using two different protocols, and eight species (Carpinus betulus L., Cornus mas L., Ficus carica L., Fraxinus excelsior L., Larix decidua Mill., Pinus montana Mill., Quercus petraea (Matt.) Liebl., Tilia tomentosa Moench), commonly used to produce bud-derivatives, have been considered as a case study. An untargeted spectroscopic fingerprint of the extracts, coupled to chemometrics, provide to be a useful tool to identify these botanicals. The targeted phytochemical fingerprint by HPLC provided a screening of the main bud-derivatives polyphenolic classes highlighting a high variability depending on both method and protocol used. Nevertheless, ultrasonic extraction proved to be less sensitive to the different extraction protocols than conventional maceration regarding the extract polyphenolic profile.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Bud-Derivatives, a Novel Source of Polyphenols and How Different Extraction Processes Affect Their Composition

Turrini

Donno

Beccaro

et al. 2020

Foods

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“…The European Food Safety Authority (EFSA) defines food supplements as “concentrated sources of nutrients or other substances with a nutritional or physiological effect, whose purpose is to supplement the normal diet”. The Food and Drug Administration (FDA) says the dietary supplements are products taken by mouth that contain a “dietary ingredient” intended to supplement the diet [ 1 , 2 , 3 , 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

Quality of Dietary Supplements Containing Plant-Derived Ingredients Reconsidered by Microbiological Approach

Ratajczak

Kamińska

Światły-Błaszkiewicz

et al. 2020

IJERPH

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Dietary supplements cover a wide range of products, the most popular are those containing plant-based ingredients. Supplements are consumed by consumers of all ages as well as by both healthy and sick people. The lack of unified regulation in this sector increases the probability that supplements are poor chemical and microbiological quality and can be dangerous for patients. The aim of this paper is to highlight selected issues associated with the microbiological quality of dietary supplements containing plant materials. We focus on the most recent reports referring to bacterial and fungal contaminations as well as the presence of mycotoxins. Dietary supplements containing plant ingredients commonly show a variety of microbial contaminants, which might be crucial for consumer safety. They often contain microorganisms potentially pathogenic to humans. Metabolites produced by microorganisms may pose a threat to the health of consumers. Because of that, in this review, we emphasize the risk that may be associated with the lack of appropriate studies of the quality of the supplements.

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“…The combination of CA and PCA has been widely used in current quality assessment, classification and identification of different medicinal plants [7][8][9]. Usually, classification and identification/ authentication of herbs extracts is carried out based on a chromatographic fingerprint [10][11][12][13][14]. Spectral analysis including ultraviolet-visible (UV-Vis) and infrared (IR) spectroscopy can also be used for these purposes [7,[15][16][17].…”

Section: Introductionmentioning

confidence: 99%

Ultraviolet-visible (Uv-Vis) spectroscopy and cluster analysis as a rapid tool for classification of medicinal plants

Cobzac¹,

Casoni²,

Badea³

et al. 2019

Studia UBB Chemia

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The ultraviolet-visible (UV-Vis) spectroscopy coupled with cluster analysis (CA) was evaluated for the classification of some medicinal plants of different geographical growing area. To have a deeper view, the experiment was carried out on herbs belonging to different families. The UV-Vis spectra of hydroalcoholic extracts were acquired in the range of 200-800 nm. The hierarchical clustering analysis (HCA) was applied to the data matrix provided by unprocessed, normalized and standardized spectra respectively. Different types of distance measuring of (dis)similarity between the samples as well as different kinds of linkage or amalgamation rule were taken into account. The best results for the classification of the selected medicinal plants were obtained using Ward's method as the amalgamation rule combined with 1-Pearson r clustering distance measurement. The obtained results reveal the ability of HCA with Ward and 1-Pearson r algorithm to identify plant species even when the raw material has different provenience areas and different pedoclimatic growing conditions. In addition, this methodology revealed a direct link between herbs from different families.

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Current trends in the analysis and quality control of food supplements based on plant extracts

Cited by 86 publications

References 70 publications

Bud-Derivatives, a Novel Source of Polyphenols and How Different Extraction Processes Affect Their Composition

Bud-Derivatives, a Novel Source of Polyphenols and How Different Extraction Processes Affect Their Composition

Quality of Dietary Supplements Containing Plant-Derived Ingredients Reconsidered by Microbiological Approach

Ultraviolet-visible (Uv-Vis) spectroscopy and cluster analysis as a rapid tool for classification of medicinal plants

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