Current Trends in Biomaterials and Bio-manufacturing

Singh, Harjit; Singh, Sunpreet; Prakash, Chander

doi:10.1007/978-3-030-13951-3_1

Cited by 45 publications

(15 citation statements)

References 129 publications

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“…Many polymers derived from biomass have been widely evaluated for biomedical applications, such as tissue engineering, drug delivery and wound healing, among others, in order to provide a green alternative to avoid the employment of toxic solvents and non-biodegradable polymers [1]. Among natural polymers, proteins such as collagen [2] and polysaccharides such as chitosan [3] may be very valuable due to their intrinsic bioactivity, biocompatibility and biodegradability [4].…”

Section: Introductionmentioning

confidence: 99%

Physicochemical and Biological Performance of Aloe Vera-Incorporated Native Collagen Films

et al. 2020

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Collagen was obtained from porcine skin by mechanical pretreatments with the aim of preserving the triple helix structure of native collagen, which was indirectly corroborated by differential scanning calorimetry (DSC) and Fourier transform infrared spectroscopy (FTIR) results. Moreover, aloe vera (AV), with inherent biological properties, was incorporated into collagen film formulations, and films were prepared by compression and characterized to assess their suitability for biomedical applications. SEM images showed that the fibrillar structure of collagen changed to a rougher structure with the addition of AV, in accordance with the decrease in the lateral packaging of collagen chains observed by XRD analysis. These results suggested interactions between collagen and AV, as observed by FTIR. Considering that AV content higher than 20 wt % did not promote further interactions, this formulation was employed for biological assays and the suitability of AV/collagen films developed for biomedical applications was confirmed.

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Section: Introductionmentioning

confidence: 99%

Physicochemical and Biological Performance of Aloe Vera-Incorporated Native Collagen Films

et al. 2020

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“…Indeed, a wide range of finishing processes, including grinding [ 22 ], honing [ 23 ], ball burnishing [ 24 ], flexible abrasive tools [ 25 ], etc., have been developed for processing the free-form surfaces of the developed implants. As per [ 26 ], the manual finishing of the implant surfaces is non-effective, imprecise, and takes more time. Apart from the conventional finishing processes, the chemical mechanical polishing is effective in polishing Ti implants [ 27 ] and to obtain mirror-polished surfaces without any contamination and reacted layers [ 28 ].…”

Section: Introductionmentioning

confidence: 99%

“…The magneto-rheological fluid assisted abrasive finishing (MRF-AF) process has been successful in producing nano-finished precise components [ 26 ]. Further, the finishing of β-phase Ti-Nb-Ta-Zr alloy is difficult because of low surface hardness as compared to other biomaterial [ 31 ].…”

Section: Introductionmentioning

confidence: 99%

Magneto-Rheological Fluid Assisted Abrasive Nanofinishing of β-Phase Ti-Nb-Ta-Zr Alloy: Parametric Appraisal and Corrosion Analysis

et al. 2020

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The present work explores the potential of magneto-rheological fluid assisted abrasive finishing (MRF-AF) for obtaining precise surface topography of an in-house developed β-phase Ti-Nb-Ta-Zr (TNTZ) alloy for orthopedic applications. Investigations have been made to study the influence of the concentration of carbonyl iron particles (CIP), rotational speed (Nt), and working gap (Gp) in response to material removal (MR) and surface roughness (Ra) of the finished sample using a design of experimental technique. Further, the corrosion performance of the finished samples has also been analyzed through simulated body fluid (SBF) testing. It has been found that the selected input process parameters significantly influenced the observed MR and Ra values at 95% confidence level. Apart from this, it has been found that Gp and Nt exhibited the maximum contribution in the optimized values of the MR and Ra, respectively. Further, the corrosion analysis of the finished samples specified that the resistance against corrosion is a direct function of the surface finish. The morphological analysis of the corroded morphologies indicated that the rough sites of the implant surface have provided the nuclei for corrosion mechanics that ultimately resulted in the shredding of the appetite layer. Overall results highlighted that the MRF-AF is a potential technique for obtaining nano-scale finishing of the high-strength β-phase Ti-Nb-Ta-Zr alloy.

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“…The EDS spectrum confirms the presence of Ti and Nb elements. Apart from the presence of base metal elements, the element O (possible oxides) was noticed as well on the surface, which is a common observation in the SPS-treated surface [35,36,37,38,39,40]. Figure 3d shows the associated XRD pattern of the sintered Ti-Nb alloy and endorses the phase composition of the sample at the different sintering temperature.…”

Section: Resultsmentioning

confidence: 77%

Surface Modification of Ti-6Al-4V Alloy by Electrical Discharge Coating Process Using Partially Sintered Ti-Nb Electrode

et al. 2019

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In the present research, a composite layer of TiO2-TiC-NbO-NbC was coated on the Ti-64 alloy using two different methods (i.e., the electric discharge coating (EDC) and electric discharge machining processes) while the Nb powder were mixed in dielectric fluid. The effect produced on the machined surfaces by both processes was reported. The influence of Nb-concentration along with the EDC key parameters (Ip and Ton) on the coated surface integrity such as surface topography, micro-cracks, coating layer thickness, coating deposition, micro-hardness has been evaluated as well. It has been noticed that in the EDC process the high peak current and high Nb-powder concentration allow improvement in the material migration, and a crack-free thick layer (215 μm) on the workpiece surface is deposited. The presence of various oxides and carbides on the coated surface further enhanced the mechanical properties, especially, the wear resistance, corrosion resistance and bioactivity. The surface hardness of the coated layer is increased from 365 HV to 1465 HV. Furthermore, the coated layer reveals a higher adhesion strength (~118 N), which permits to enhance the wear resistance of the Ti-64 alloy. This proposed technology allows modification of the mechanical properties and surface characteristics according to an orthopedic implant’s requirements.

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Current Trends in Biomaterials and Bio-manufacturing

Cited by 45 publications

References 129 publications

Physicochemical and Biological Performance of Aloe Vera-Incorporated Native Collagen Films

Physicochemical and Biological Performance of Aloe Vera-Incorporated Native Collagen Films

Magneto-Rheological Fluid Assisted Abrasive Nanofinishing of β-Phase Ti-Nb-Ta-Zr Alloy: Parametric Appraisal and Corrosion Analysis

Surface Modification of Ti-6Al-4V Alloy by Electrical Discharge Coating Process Using Partially Sintered Ti-Nb Electrode

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