Current trends and new developments in HIV research and periodontal diseases

Ryder, Mark I.; Shiboski, Caroline H.; Yao, Tzy‐Jyun; Moscicki, Anna‐Barbara

doi:10.1111/prd.12321

Cited by 22 publications

(23 citation statements)

References 165 publications

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“…Patients with HIV or a compromised immune function, represent a group at higher risk of systemic and oral manifestations [91,92]. PD associated with HIV has been studied by several researchers [93][94][95], this possible association has been considered since PD is a source of chronic inflammation [96]. Some authors suggest that HIV is a contributing factor in the prevalence of PD.…”

Section: Hiv (Human Immunodeficiency Virus)mentioning

confidence: 99%

Is periodontal disease a risk factor for severe COVID-19 illness?

et al. 2020

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Periodontal disease (PD) comprises a group of diseases involving inflammatory aspects of the host and dysbiotic events that affect periodontal tissues and could have systemic implications. Diverse factors and comorbidities have been closely associated with PD such as diabetes, obesity, aging, hypertension, and so on; although, underlying mechanisms or causal associations have not been established completely. Interestingly, these same factors have been widely associated with progression or severe coronavirus disease 2019 (COVID-19), an illness caused by coronavirus SARS-CoV-2. Since inflammatory and dysbiotic factors as well as comorbidities affect systemic health, it is possible that periodontal status indicates the risk of complication of COVID-19. However, assessment of oral health history including periodontal status in COVID-19 patients has not been reported. Knowing PD is associated with severe COVID-19 could help identify risk groups and establish pertinent recommendations. Evaluation of hypothesis: Shared risk factors by PD and severe COVID-19 illness AgingAging is considered a process that causes degenerative changes at the cellular level and sometimes leads to various diseases that can be

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Section: Hiv (Human Immunodeficiency Virus)mentioning

confidence: 99%

Is periodontal disease a risk factor for severe COVID-19 illness?

et al. 2020

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“…Periodontal diseases are completely within the framework of the potential consequences of HIV [ 6 , 7 ]. They are multifactorial chronic infectious diseases, classically occurring around the age of 35–40 years old and are part of a rationale of co-morbidities.…”

Section: Introductionmentioning

confidence: 99%

Stage II and stage III periodontitis clinical burdens of HIV-1 undergoing antiretroviral therapy

et al. 2021

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Objectives The aim of this retrospective cross-sectional study was to estimate the association of HIV-1 infection under highly active antiretroviral treatment (HAART) on the clinical parameters of periodontitis. Materials and methods A total of 205 patients were divided in two groups: 74 HIV + and 131 HIV − . Periodontal probing depth (PPD), clinical attachment loss (CAL), bleeding on probing (BOP), and visible supragingival biofilm (VSB) were recorded. The association of HIV-1 infection with the presence of at least 3 sites with PPD ≥ 5 mm and/or CAL ≥ 4 mm in non-adjacent teeth was estimated using binary logistic regression models. Results The variables HIV-1 infection (OR = 5.53, p < 0.0001, 95% CI: 2.45–13.64), age [range 35–50 years old (OR = 5.73, p < 0.0001, 95% CI: 2.49–13.20); > 50 years old (OR = 6.29, p = 0.002, 95% CI: 1.94–20.42)], and VSB (OR = 23.68, p < 0.0001, 95% CI: 8.07–69.53) showed a significant direct association with BOP outcome. Conclusions HIV-1 infection under HAART did not have association with the presence of at least 3 sites with PPD ≥ 5 mm and/or CAL ≥ 4 mm. However, HIV patients on HAART had direct association of HIV-1 infection with BOP and an inverse association with PPD. Clinical relevance These results support that monitoring gingival bleeding associated with oral prophylaxis would be beneficial in the prevention and management of periodontitis in HIV-1 patients on HAART.

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“…59 For example, explaining how preventive periodontal treatment and oral hygiene interventions can lead to improvements in systemic inflammation, HIV outcomes, and other co-morbidities associated with HIV can help exemplify how disclosure to dentists is a separate entity from personal disclosure. [60][61][62] Limitations of this study include the collection of selfreported data, so potential information bias must be considered on account of social desirability, which can occur when research subjects participating in self-reported questionnaires provide responses that are considered more socially favorable or underreport responses that are more accurate but socially undesirable. 63 Social desirability bias can be a deterrent against women living with HIV reporting that they had not disclosed their serostatus to a dentist, which could lead to an overestimate of the disclosure percentage.…”

Section: Discussionmentioning

confidence: 99%

“…Overall, the decision‐making that precipitates selectivity of disclosure involves calculations of the perceived consequences of informing a particular individual 59 ; as such, it is critical that women living with HIV are informed of the positive implications of disclosing to their dentists as a conduit to preventing dental disease that is distinct from their disclosure to personal relations 59 . For example, explaining how preventive periodontal treatment and oral hygiene interventions can lead to improvements in systemic inflammation, HIV outcomes, and other co‐morbidities associated with HIV can help exemplify how disclosure to dentists is a separate entity from personal disclosure 60–62 …”

Section: Discussionmentioning

confidence: 99%

Women's HIV disclosure to the dentist: Does frequent contact matter?

Parish

Feaster

Pereyra

et al. 2020

J Public Health Dent

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Objectives: Research has shown inconsistent patterns of patients' HIV serostatus disclosure to their dentists. Common barriers to disclosure have included confidentiality concerns, fear of treatment refusal, and discrimination. This study evaluated the prevalence of HIV serostatus disclosure to the dentist, whether the frequency of dental care utilization is associated with disclosure, and reasons for nondisclosure among women living with HIV. Methods: We administered a cross-sectional oral health survey to 1,526 women living with HIV in the Women's Interagency HIV Study including questions regarding HIV serostatus disclosure to dentists. Logistic regression models were used to analyze the association between dental care utilization (at least annually versus less than annually) and HIV serostatus disclosure to dentists. Results: Overall, 83 percent of women reported that they disclosed their HIV serostatus to their dentist. The most common reasons for nondisclosure were: a) the dentist did not ask, b) believing that the dentist did not need to know, and c) not having a consistent dentist. In the multivariable logistic regression model, at least annual dental care utilization, compared to less than annual, led to a 59 percent reduction in the odds of HIV nondisclosure to the dentist. Discussion: Study findings highlight that dentists who see their patients infrequently should consider methods for overcoming barriers to HIV nondisclosure and the possibility that their patient's HIV serostatus is undisclosed. Educating women living with HIV about how disclosure to dentists is a critical component of their dental assessment and treatment, and how preventive dental treatment can improve overall health outcomes, is important.

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Current trends and new developments in HIV research and periodontal diseases

Cited by 22 publications

References 165 publications

Is periodontal disease a risk factor for severe COVID-19 illness?

Is periodontal disease a risk factor for severe COVID-19 illness?

Stage II and stage III periodontitis clinical burdens of HIV-1 undergoing antiretroviral therapy

Women's HIV disclosure to the dentist: Does frequent contact matter?

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