Current State of Combined Heart–Liver Transplantation in the United States

Te, Helen S.; Anderson, Allen S.; Millis, J. Michael; Jeevanandam, Valluvan; Jensen, Donald M.

doi:10.1016/j.healun.2008.04.004

Cited by 80 publications

(65 citation statements)

References 42 publications

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“…Rather than transplanting the liver following the heart transplant and weaning from CPB, which appears to be the standard approach, these cases are distinguished by the fact that both organs were transplanted during CPB. [4][5][6][7][8][9][10][11] It is difficult to compare surgical strategies for CHLT because only scant data are provided in the literature. Bearing this caveat in mind, the following comparisons may be of interest.…”

Section: Discussionmentioning

confidence: 99%

“…3 According to the few published reports, the preferred technique is transplantation of the liver, with or without veno-venous bypass, once the heart transplantation has been completed and the patient has been separated from cardiopulmonary bypass (CPB). [4][5][6][7][8][9][10][11] The purported advantages of this strategy include a shorter period of myocardial ischemia and a reduced length of CPB with its attendant problems of hemodilution, platelet dysfunction, and inflammation. Ostensibly, there is the benefit of improved cardiac function of the transplanted heart to support the considerable hemodynamic alterations associated with liver transplantation.…”

Section: Résumémentioning

confidence: 99%

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Combined heart and liver transplantation on cardiopulmonary bypass: report of four cases

Hennessey

Backman

Cecere

et al. 2010

Can J Anesth/J Can Anesth

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Section: Discussionmentioning

confidence: 99%

Section: Résumémentioning

confidence: 99%

Combined heart and liver transplantation on cardiopulmonary bypass: report of four cases

Hennessey

Backman

Cecere

et al. 2010

Can J Anesth/J Can Anesth

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“…Patients with chronic hepatitis C or chronic hepatitis B should be treated before HTx to avoid antiviral drug intake after HTx which may be associated with graft rejection [125] . Finally, patients with heart failure and irreversible cirrhosis could be offered combined heart and liver transplantation [126] .…”

Section: Heart Transplantationmentioning

confidence: 99%

Hepato-cardiac disorders

Fouad¹,

Yehia²

2014

WJH

111

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Understanding the mutual relationship between the liver and the heart is important for both hepatologists and cardiologists. Hepato�cardiac diseases can be classified into heart diseases affecting the liver, liver diseases affecting the heart, and conditions affecting the heart and the liver at the same time. �ifferential diagnoses of liver injury are extremely important in a cardiologist's clinical practice calling for collaboration between cardiologists and hepatologists due to the many other diseases that can affect the liver and mimic haemodynamic injury. Acute and chronic heart failure may lead to acute ischemic hepatitis or chronic conges� tive hepatopathy. Treatment in these cases should be directed to the primary heart disease. In patients with advanced liver disease, cirrhotic cardiomyopathy may develop including hemodynamic changes, diastolic and systolic dysfunctions, reduced cardiac performance and electrophysiological abnormalities. Cardiac evaluation is important for patients with liver diseases especially before and after liver transplantation. Liver transplanta� tion may lead to the improvement of all cardiac chang� es and the reversal of cirrhotic cardiomyopathy. There are systemic diseases that may affect both the liver and the heart concomitantly including congenital, metabolic and inflammatory diseases as well as alcoholism. This review highlights these hepatocardiac diseases

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“…Current indications for CHLT can be summarized as end stage heart and liver disease, and end stage heart disease which need liver transplantation to correct an underlying disorder. Familial amyloid polyneuropathy and heart failure with associated cardiac cirrhosis are the most common indications for CHLT (14,15,17,18).…”

Section: There Were 208 Chlt Operations Performed In the Unitedmentioning

confidence: 99%

Combined Heart and Liver Transplantation: The Asan Medical Center Experience

Choi

Yun

Jung

et al. 2017

Korean J Transplant

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Combined heart-liver transplantation (CHLT) is an increasingly accepted treatment for select patients with advanced heart and liver disease. However, CHLT are infrequently performed, despite growing optimism about their effectiveness. Here, we report Asan Medical Center experience with CHLT in three patients presenting with advanced heart and liver failure. One patient died of brain swelling because of intractable hyperammonemia on postoperative day 9. The two other patients were still alive at 53 and 9 months postsurgery. None of these patients required readmission for cardiac or hepatic graft dysfunction and no rejection episodes were detected on routine cardiac biopsies. This is the first report of CHLT cases from Korea.

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Current State of Combined Heart–Liver Transplantation in the United States

Cited by 80 publications

References 42 publications

Combined heart and liver transplantation on cardiopulmonary bypass: report of four cases

Combined heart and liver transplantation on cardiopulmonary bypass: report of four cases

Hepato-cardiac disorders

Combined Heart and Liver Transplantation: The Asan Medical Center Experience

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