Current methods for synthesis of magnetic nanoparticles

Majidi, Sima; Sehrig, Fatemeh Zeinali; Farkhani, Samad Mussa; Soleymani-Goloujeh, Mehdi; Akbarzadeh, Abolfazl

doi:10.3109/21691401.2014.982802

Cited by 304 publications

(193 citation statements)

References 164 publications

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“…Several methods of MNPs synthesis were developed and are currently used [41,42]. The most common method for the production of MNPs is the chemical co-precipitation of iron salts [41].…”

Section: Synthesis and Characterization Of Mnpsmentioning

confidence: 99%

Magnetic Nanoparticles for Antibiotics Detection

2017

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Widespread use of antibiotics has led to pollution of waterways, potentially creating resistance among freshwater bacterial communities. Microorganisms resistant to commonly prescribed antibiotics (superbug) have dramatically increased over the last decades. The presence of antibiotics in waters, in food and beverages in both their un-metabolized and metabolized forms are of interest for humans. This is due to daily exposure in small quantities, that, when accumulated, could lead to development of drug resistance to antibiotics, or multiply the risk of allergic reaction. Conventional analytical methods used to quantify antibiotics are relatively expensive and generally require long analysis time associated with the difficulties to perform field analyses. In this context, electrochemical and optical based sensing devices are of interest, offering great potentials for a broad range of analytical applications. This review will focus on the application of magnetic nanoparticles in the design of different analytical methods, mainly sensors, used for the detection of antibiotics in different matrices (human fluids, the environmental, food and beverages samples).

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“…Several methods of MNPs synthesis were developed and are currently used [41,42]. The most common method for the production of MNPs is the chemical co-precipitation of iron salts [41].…”

Section: Synthesis and Characterization Of Mnpsmentioning

confidence: 99%

Magnetic Nanoparticles for Antibiotics Detection

2017

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“…[30]. The synthesis of the above-mentioned magnetic nanoparticles (MNPs) has attracted much attention during the last few years and a list of efficient routes to attain shape-controlled and highly stable magnetic nanoparticles with narrow size distribution has been recently reported by Majidi [31]. Several popular methods including coprecipitation, micro-emulsion, thermal decomposition, solvothermal, sonochemical, microwave-assisted, chemical vapour deposition, combustion, carbon arc, and laser pyrolysis, for the synthesis of magnetic nanoparticles have been discussed with detailed references.…”

Section: Different Types Of Nanoparticlesmentioning

confidence: 99%

A review on hyperthermia via nanoparticle-mediated therapy

et al. 2017

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“…[1][2][3][4] Such applications explore the biggest advantages of using SPIONs: biocompatibility and satisfactory magnetic response at applied magnetic field (superparamagnetic character). 5,6 The surface of the magnetic nanoparticles should be modified, not only in order to prevent oxidation and aggregation, but also to provide colloidal stability, reduced magnetic susceptibility, as well as to expand the effectiveness of cellular uptake and biodistribution. The hydroxyl groups present on the surface of nanoparticles can function as an anchor point for various types of compounds such as oleic acid, which is commonly used in the synthesis of magnetic ferrofluids.…”

mentioning

confidence: 99%

Preliminary Evaluation of Novel Triglyceride-Based Nanocomposites for Biomedical Applications

Almeida¹,

Gallo²,

Silva³

et al. 2017

J. Braz. Chem. Soc.

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This work describes the development and characterization of triglyceride-based magnetic nanocomposites for application in magnetic hyperthermia and controlled drug delivery. The magnetic solid lipid nanocomposites (MSLN) constituted by mixtures of trilaurin-tricaprylin and trilaurin-tricaprin have been successfully obtained by emulsification-solvent evaporation method. The developed MSLNs were subjected to an external oscillating magnetic field and showed significant hyperthermia. The samples were exposed to frequencies of 688 and 869 kHz causing, respectively, a temperature increase of 15.5 and 22.7 °C (trilaurin-tricaprylin) and 17.3 and 26.1 °C (trilaurin-tricaprin). Also, in vitro assays in the absence of magnetic field showed that the triglyceride-based formulations were able first to encapsulate and then to sustained release an antitumoural hydrophobic drug. After 72 h of assay trilaurin-tricaprylin and trilaurin-tricaprin released 73 and 55% of their cargo, respectively. In addition, MSLN exhibited low in vitro cytotoxic activity against human neutrophils.Keywords: lipid mixture, magnetic hyperthermia, drug delivery, oncocalyxone-A IntroductionNanotechnology is an expanding sector and the use of superparamagnetic iron oxide nanoparticles (SPIONs) is attracting increasing attention in several areas. SPIONs are widely employed for biotechnological applications through the development of magnetic systems for use in: cell separation, as contrast agents for magnetic resonance imaging (MRI), magnetic hyperthermia, targeted bioactive compounds delivery and biosensors. [1][2][3][4] Such applications explore the biggest advantages of using SPIONs: biocompatibility and satisfactory magnetic response at applied magnetic field (superparamagnetic character). 5,6 The surface of the magnetic nanoparticles should be modified, not only in order to prevent oxidation and aggregation, but also to provide colloidal stability, reduced magnetic susceptibility, as well as to expand the effectiveness of cellular uptake and biodistribution. The hydroxyl groups present on the surface of nanoparticles can function as an anchor point for various types of compounds such as oleic acid, which is commonly used in the synthesis of magnetic ferrofluids. The criteria adopted to select the appropriate coating of magnetic nanoparticles depends mainly on the intended application. In the case of this research, magnetic nanoparticles made of iron oxide were coated with oleic acid (Fe 3 O 4 @OA) for subsequent incorporation into lipid carriers. 7-9The lipid carriers have been widely used as they also possess excellent characteristics such as biocompatibility Preliminary Evaluation of Novel Triglyceride-Based Nanocomposites for Biomedical Applications J. Braz. Chem. Soc. 1548 and versatility, and they have been proposed for the delivery of bioactive compounds by oral, intravenous, topical and parenteral routes. 10,11The solid lipid nanoparticles (SLNs) emerged in the early 90's and currently are alternative encapsulation systems and carriers o...

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Current methods for synthesis of magnetic nanoparticles

Cited by 304 publications

References 164 publications

Magnetic Nanoparticles for Antibiotics Detection

Magnetic Nanoparticles for Antibiotics Detection

A review on hyperthermia via nanoparticle-mediated therapy

Preliminary Evaluation of Novel Triglyceride-Based Nanocomposites for Biomedical Applications

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