Current Epidemiology of Mild Cognitive Impairment and Other Predementia Syndromes

Panza, Francesco; D’Introno, Alessia; Colacicco, Anna M.; Capurso, Cristiano; Parigi, Angelo Del; Caselli, Richard J.; Pilotto, Alberto; Argentieri, Giovanni; Scapicchio, Pierluigi; Scafato, Emanuele; Capurso, Antonio; Solfrizzi, Vincenzo

doi:10.1097/00019442-200508000-00002

Cited by 196 publications

(83 citation statements)

References 75 publications

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“…Finally, as only 50% of the randomly selected patients consented to participate in the study, selection bias might also play a role in the sense of an overrepresentation of more healthy, cognitively unimpaired elderly. On the other hand, the prevalence rates of MCI found in our sample are comparable to other well-designed studies (2,37).…”

Section: Figuresupporting

confidence: 91%

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Do general practitioners recognize mild cognitive impairment in their patients?

Kaduszkiewicz

Zimmermann

Bussche

et al. 2010

The Journal of nutrition, health and aging

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The results show that GPs recognise MCI in a very limited number of cases when based on clinical impression only. A further development of the MCI concept and its operationalisation is necessary. Emphasis should be placed on validated, reliable and standardised tests for routine use in primary care encompassing other than only cognitive domains and on case finding approaches rather than on screening. Then a better attention and qualification of GPs with regard to the recognition of MCI might be achievable.

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Section: Figuresupporting

confidence: 91%

“…Depending on sample and study methodology, the prevalence of MCI ranges from 1% to 19%. Conversion rates to dementia between 4% and 11% per year were found (2). Persons with MCI can thus be regarded as a population at an elevated risk for developing dementia.…”

Section: Introductionmentioning

confidence: 95%

Do general practitioners recognize mild cognitive impairment in their patients?

Kaduszkiewicz

Zimmermann

Bussche

et al. 2010

The Journal of nutrition, health and aging

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“…In most, the focus was on inflammatory processes thought to be associated with aging. The Italian Longitudinal Study on Aging (ILSA) found that vascular risk factors influenced incident mild cognitive impairment and the rate of progression to dementia (Solfrizzi et al, 2004;Panza et al, 2005). The link between vascular and long term cognitive health suggests that dietary components that reduce vascular risk may also reduce risk of cognitive decline or Alzheimer's disease development.…”

Section: Wine Polyphenol Actions and Metabolismmentioning

confidence: 99%

Wine and health: state of proofs and research needs

Walzem

2008

Inflammopharmacol

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Regular moderate wine consumption is often associated with reduced morbidity and mortality from to a variety of chronic diseases in which inflammation is a root cause. Wine comes in a wide variety of styles that contain quite different ethanol and polyphenol contents. Controversy remains as to whether the alcohol or polyphenols contribute more to the health benefits of regular moderate wine consumption. The variety of wines available to consumers can be expected to affect health differently in accordance with a particular wine's total polyphenolic content and spectrum of individual polyphenols. The overall effect of wine consumption on health depends upon the total amounts consumed, the style and possibly the pattern of consumption. The apparent effect of wine consumption may be modified by the non-wine diet composition of the consumer in that alcohol may appear as the primary component in consumers with high fruit, vegetable and whole grain intakes while phytochemical benefit may become significant in diets where wine is the primary dietary source of phytochemical. In this review, wine polyphenol mechanisms of action will be reviewed in connection with the mechanism the development of atherosclerotic cardiovascular disease (ASCVD). Selected clinical studies published in 2004-2008 were reviewed. Experimental requirements for valid clinical studies, translation of in vitro to in vivo application and areas where additional evidence needs to be developed were identified.

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“…In the fifteen year period since its publication, public awareness has grown and diagnostic approaches improved and as a consequence, there has been a much greater emphasis on the importance of early intervention in the community at a stage when a patient may benefit the most (Moniz-Cook and Woods, 1997). To reflect this emphasis, older people with MCI have been included in this review on the basis that in many cases they will progress to developing dementia (at a rate of approximately 15% per year, Panza et al 2005). A range of psychotherapeutic approaches will be investigated including support groups for adjustment to diagnosis, individual psychotherapy, group programs, life review, and intergenerational community schemes.…”

Section: Introductionmentioning

confidence: 99%

Adjustment, depression, and anxiety in mild cognitive impairment and early dementia: a systematic review of psychological intervention studies

Regan

Varanelli

2013

Int. Psychogeriatr.

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Several studies have demonstrated positive findings in the treatment of depression in older adults with early dementia using problem solving and modified cognitive behavior therapy (CBT) approaches. Amongst the large range of approaches trialed to improve adjustment and quality of life for patients with MCI and early dementia, some approaches, such as modified CBT, have shown promise. There is a need for replication studies using more rigorous methodology before clear clinical recommendations can be made.

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Current Epidemiology of Mild Cognitive Impairment and Other Predementia Syndromes

Cited by 196 publications

References 75 publications

Do general practitioners recognize mild cognitive impairment in their patients?

Do general practitioners recognize mild cognitive impairment in their patients?

Wine and health: state of proofs and research needs

Adjustment, depression, and anxiety in mild cognitive impairment and early dementia: a systematic review of psychological intervention studies

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