Current concepts in the management of primary hyperparathyroidism

Iyer, N. Gopalakrishna; Shaha, Ashok R.

doi:10.1007/s13193-010-0023-9

Cited by 4 publications

(1 citation statement)

References 21 publications

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“…This result revealed that the excitability of the cerebral cortex was elevated in the acute and subacute phases and subsequently suppressed in the chronic phase. Another study showed that non-primed iTBS could increase the input-output curve of motor-evoked potentials (IO-MEP), which revealed that iTBS could increase cortical excitability ( 46 ). For the recovery-promoting effect of iTBS, increasing the excitability of suppressed cortex is the primary therapeutic mechanism.…”

Section: Discussionmentioning

confidence: 99%

Intermittent theta-burst stimulation with physical exercise improves poststroke motor function: A systemic review and meta-analysis

et al. 2022

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BackgroundIntermittent theta-burst stimulation (iTBS) is an optimized rTMS modality that could modulate the excitability of neural structures. Several studies have been conducted to investigate the efficacy of iTBS in improving the motor function of stroke patients. However, the specific role of iTBS in motor function recovery after stroke is unclear. Hence, in our study, we performed a meta-analysis to investigate the efficacy of iTBS for the motor function improvement of stroke patients.MethodsMEDLINE, Embase, and Cochrane Library were searched until May 2022 for randomized controlled trials (RCTs).ResultsThirteen RCTs with 334 patients were finally included in our study. The primary endpoints were the Fugl-Meyer assessment scale (FMA) and Motor Assessment Scale (MAS) change from baseline. We found that iTBS led to a significant reduction in FMA score (P = 0.002) but not in MAS score (P = 0.24) compared with the sham group. Moreover, standard 600-pulse stimulation showed a better effect on motor function improvement than the sham group (P = 0.004), however, 1200-pulse iTBS showed no effect on motor function improvement after stroke (P = 0.23). The effect of iTBS for improving motor function only exists in chronic stroke patients (P = 0.02) but not in subacute patients (P = 0.27).ConclusionThis study supports that iTBS has good efficacy for improving motor function in stroke patients. Therefore, standard 600-pulse stimulation iTBS therapy is proper management and treatment for chronic stroke.

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Section: Discussionmentioning

confidence: 99%

Intermittent theta-burst stimulation with physical exercise improves poststroke motor function: A systemic review and meta-analysis

et al. 2022

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Radioguided occult lesion localization for minimally invasive parathyroidectomy

Ilgan

Özbaş²,

Bilezikçi³

et al. 2014

Nuclear Medicine Communications

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The use of ROLL-MIP in patients with PHPT due to a single parathyroid adenoma in the neck is technically safe and effective. It is more valuable in scintigraphy-negative patients when parathyroid adenoma is either demonstrated on ultrasonography by typical findings or confirmed by PTH washout. The ROLL-MIP technique does not impair the postoperative histopathologic examination of the parathyroid glands.

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“The Importance of ROLL Tecnique at Surgical Treatment of Paratyroid Adenomas-Our Clinical Experiences”

Güven¹,

Karadeniz²,

Filik³

et al. 2020

Sakarya Medical Journal

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Objective The most important cause of primary hyperparathyroidism (PHP) is parathyroid adenomas. While the reason is mostly the adenomas originating from the parathyroid glands, which are mostly localized around the thyroid gland, ectopic localization can also be seen. The gold standard is surgical excision of adenoma. One of the most important factors affecting surgical success is the correct localization of adenoma preoperatively. Our aim is to investigate the contribution of ROLL technique to the surgical treatment of parathyroid adenomas. Materials and Methods 40 cases, which were directed due to clinic and laboratory data or incidentally detected, clearly localized preoperatively with ultrasonography (US) and/or scintigraphy findings and surgically excised using ROLL technique between November 2017 and October 2019 were included in the study. Cases where could not be clearly localized preoperatively on US were excluded from the study. The preoperative and postoperative PTH (parathyroid hormone) and Ca (calcium) values were analyzed retrospectively. Results Postoperative PTH and Ca values were found to decrease in all cases. Histopathological results were confirmed as parathyroid adenoma. In cases, which were operated by using ROLL technique, the duration of the operation was significantly reduced and therefore shorter anesthesia and earlier hospital discharge were provided. PTH values were found to be increased only in 3 cases in postoperative controls, and no other problems were detected in the follow-ups of other cases. Conclusions In surgical excision of parathyroid adenoma, the ROLL technique is a safe adjuvant method that can contribute positively to the duration and process of treatment. Keywords parathyroid adenoma; ultrasonography; minimally invasive parathyroidectomy Öz Amaç Primer hiperparatiroidizmin (PHP) en önemli nedeni paratiroid adenomlarıdır. Sebep, çoğunlukla tiroid bezi çevresinde yerleşmiş paratiroid bezlerinden kaynaklanan adenomlar olmakla birlikte daha nadir olarak ektopik yerleşim de görülebilmektedir. Tedavide altın standart cerrahi olarak adenomun eksizyonudur. Cerrahi başarıyı etkileyen en önemli faktörlerden birisi ise preoperatif olarak adenomun doğru olarak lokalize edilebilmesidir. Bu çalışmada amaç, ROLL tekniğinin paratiroid adenomlarının cerrahi tedavisinde tedaviye katkısını araştırmaktır. Gereç ve Yöntemler Çalışmaya Kasım 2017 ile Ekim 2019 yılları arasında, klinik ve laboratuvar verileri nedeniyle yönlendirilen veya insidental olarak saptanan, ultrasonografi ve/veya sintigrafi bulgularıyla preoperatif olarak net olarak lokalize edilen ve ROLL tekniği kullanılarak cerrahi eksizyon yapılan 40 olgu dahil edilmiştir. Herhangi bir nedenle ROLL tekniği uygulanamayan veya ultrasonografide preoperatif net olarak lokalize edilemeyen olgular çalışma dışı bırakılmıştır. Çalışmaya dahil edilen tüm olgulara ait preoperatif ve postoperatif PTH (parathormon) ve Ca (kalsiyum) değerleri retrospektif olarak incelenerek ROLL tekniğinin tedavi sürecine katkısı araştırılmıştır. Bulgular Çalı...

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Current concepts in the management of primary hyperparathyroidism

Cited by 4 publications

References 21 publications

Intermittent theta-burst stimulation with physical exercise improves poststroke motor function: A systemic review and meta-analysis

Intermittent theta-burst stimulation with physical exercise improves poststroke motor function: A systemic review and meta-analysis

Radioguided occult lesion localization for minimally invasive parathyroidectomy

“The Importance of ROLL Tecnique at Surgical Treatment of Paratyroid Adenomas-Our Clinical Experiences”

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