Current biocompatible materials in oral regeneration: a comprehensive overview of composite materials

Tahmasebi, Elahe; Alam, Mostafa; Yazdanian, Mohsen; Tebyanian, Hamid; Yazdanian, Alireza; Seifalian, Alexander M.; Mosaddad, Seyed Ali

doi:10.1016/j.jmrt.2020.08.042

Cited by 47 publications

(35 citation statements)

References 120 publications

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“…Nanotechnology, a vast field, is receiving considerable attention. Bio nanotech (microbes to higher plants) has gained global attention since chemical synthesizing produces very few NPs and is toxic and unsustainable [32][33][34][35][36][37]. A study conducted by Barbosa et al described the use of Brazilian propolis to synthesize silver nanoparticles (AgNP-P) and assess their antimicrobial properties.…”

Section: Discussionmentioning

confidence: 99%

Green Synthesize and Characterization of Copper Nanoparticles Using Iranian Propolis Extracts

Hajizadeh

Harzandi

Babapour

et al. 2022

Advances in Materials Science and Engineering

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The propolis produced by bees is used by them to protect their hives. The cavity inside the hive’s walls is filled in during cold days to reduce entry points and mummify any intruders to ensure their survival. A current focus in nanotechnology and nanoscience is the green biosynthesis of nanoparticles (NPs) using biomaterials. Research on green methods for making metal oxide NPs is gaining momentum to safeguard the environment from the potential dangers associated with toxic chemicals. This study aimed to synthesize copper NPs (CuNPs) via propolis extraction, a novel application of nanoscience. The study was conducted under a range of pH, time conditions, and concentration ratios, and its properties were characterized by UV-Vis absorption spectra, XRD, and FTIR. An FTIR analysis revealed that compounds found in propolis extract could have an effect on the surface modification of the synthesized NPs. The propolis (Khalkhal) extract spectrum exhibited a sharp peak at 3422 cm−1, caused by free hydroxyl groups and their intra/intermolecular hydrogen bonds. There were sharp peaks at 2925, 1637, and 1515 to 1076 cm−1 associated with the C = O and C = C aromatic stretching frequencies. According to UV-Vis spectrophotometry investigation, CuO NPs exhibit a characteristic peak at 385 nm, showing significant surface plasmon resonance (SPR) with propolis (Khalkhal) extract. Furthermore, specific wavelengths of CuO NPs demonstrate peaks at 243, 292, and 350 nm for propolis (Gilan) extract. The green synthesis of CuNPs from Gilan and Khalkhal propolis can be an appropriate candidate for clinical applications such as drug delivery systems, drug formulation, and biomedical applications.

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Section: Discussionmentioning

confidence: 99%

Green Synthesize and Characterization of Copper Nanoparticles Using Iranian Propolis Extracts

Hajizadeh

Harzandi

Babapour

et al. 2022

Advances in Materials Science and Engineering

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“…Scaffolds and biomaterials are important factors supporting tissue regeneration. They must mimic, in vitro, the physiological environment necessary for cellular growth, expansion, and differentiation [ 99 , 100 ]. Scaffolds must be biocompatible, ensure adequate diffusion of nutrients, and have porous structures that allow cell penetration.…”

Section: Overview Of Different Types Of Dental Stem Cellsmentioning

confidence: 99%

Hypes and Hopes of Stem Cell Therapies in Dentistry: a Review

Baena

Casasco

Monti

2022

Stem Cell Rev and Rep

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One of the most exciting advances in life science research is the development of 3D cell culture systems to obtain complex structures called organoids and spheroids. These 3D cultures closely mimic in vivo conditions, where cells can grow and interact with their surroundings. This allows us to better study the spatio-temporal dynamics of organogenesis and organ function. Furthermore, physiologically relevant organoids cultures can be used for basic research, medical research, and drug discovery. Although most of the research thus far focuses on the development of heart, liver, kidney, and brain organoids, to name a few, most recently, these structures were obtained using dental stem cells to study in vitro tooth regeneration. This review aims to present the most up-to-date research showing how dental stem cells can be grown on specific biomaterials to induce their differentiation in 3D. The possibility of combining engineering and biology principles to replicate and/or increase tissue function has been an emerging and exciting field in medicine. The use of this methodology in dentistry has already yielded many interesting results paving the way for the improvement of dental care and successful therapies. Graphical abstract

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“…Overall, a growing amount of evidence is supporting the fact that the use of polymer composites might be of great aid in those issues affecting the oral structures, including the periodontal structures, alveolar process, and jawbone. However, future studies should address some issues in this area, including the development of less invasive technologies, the creation of drug carrier and delivery scaffolds, and the establishment of optimized protocols and approaches to achieve complete restoration of craniofacial and oral alterations, in terms of either hard or soft tissues [ 123 ].…”

Section: Polymer Composites and Jawbone Regenerationmentioning

confidence: 99%

Applications of Polymeric Composites in Bone Tissue Engineering and Jawbone Regeneration

et al. 2021

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Polymer-based composites are a group of biomaterials that exert synergic and combined activity. There are multiple reported uses of these composites in multiple biomedical areas, such as drug carriers, in wound dressings, and, more prominently, in tissue engineering and regenerative medicine. Bone grafting is a promising field in the use of polymeric composites, as this is the second most frequently transplanted organ in the United States. Advances in novel biomaterials, such as polymeric composites, will undoubtedly be of great aid in bone tissue engineering and regeneration. In this paper, a general view of bone structure and polymeric composites will be given, discussing the potential role of these components in bone tissue. Moreover, the most relevant jawbone and maxillofacial applications of polymeric composites will be revised in this article, collecting the main knowledge about this topic and emphasizing the need of further clinical studies in humans.

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Current biocompatible materials in oral regeneration: a comprehensive overview of composite materials

Cited by 47 publications

References 120 publications

Green Synthesize and Characterization of Copper Nanoparticles Using Iranian Propolis Extracts

Green Synthesize and Characterization of Copper Nanoparticles Using Iranian Propolis Extracts

Hypes and Hopes of Stem Cell Therapies in Dentistry: a Review

Applications of Polymeric Composites in Bone Tissue Engineering and Jawbone Regeneration

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