Curative surgery for primary squamous cell carcinoma of the liver: a rare case study

Okuda, Yasuhiro; Abe, T.; Ikeda, Mario; Kurihara, Keisuke; Shimizu, Akinori; Oshita, Akihiko; Yonehara, Shuji; Hanada, Keiji

doi:10.1007/s12328-022-01740-3

Cited by 3 publications

(4 citation statements)

References 30 publications

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“…Finally, in combination with histopathological findings, PSCCL can be confirmed. Nonetheless, Yamada et al confirmed the pathological diagnosis of PSCCL by EUS‐FNA biopsy before surgery, 12,19 and Hofman et al believed that EUS‐FNA was necessary to distinguish metastatic liver cancer from primary liver cancer 42 . At present, surgical resection is the main treatment for this disease, 9,13,15 and surgical resection is very important for the overall prognosis of patients.…”

Section: Discussionmentioning

confidence: 99%

“…[5][6][7]17,18 Enhanced CT findings are as follows (Table 1): (1) slight delayed enhancement at the edge of the lesion, but no enhancement at the center of the lesion in the three phases. 9,10,12,19 (2) Mild enhancement in the focal center and margin in the arterial phase, and continuous enhancement in the focal center and margin in the portal venous and delayed phases, although the density of the lesion after enhancement was still lower than that of the liver parenchyma. 5,20,21 However, in a study by Lee et al, 13 enhanced CT demonstrated a delayed filling enhancement mode, similar to cholangiocarcinoma.…”

Section: Ct Characteristics Of Pscclmentioning

confidence: 99%

“…On CT imaging of PSCCL, most of them appear as low‐density masses with a single round or lobulated outline in the liver with an unclear boundary, 12,15,16 often accompanied by intrahepatic bile duct dilatation and intrahepatic bile duct stones 5–7,17,18 . Enhanced CT findings are as follows (Table 1): (1) slight delayed enhancement at the edge of the lesion, but no enhancement at the center of the lesion in the three phases 9,10,12,19 . (2) Mild enhancement in the focal center and margin in the arterial phase, and continuous enhancement in the focal center and margin in the portal venous and delayed phases, although the density of the lesion after enhancement was still lower than that of the liver parenchyma 5,20,21 .…”

Section: Imaging Manifestationsmentioning

confidence: 99%

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Diagnostic value of imaging modalities in primary squamous cell carcinoma of the liver

Song

Shi

Zhang

et al. 2023

J of Clinical Ultrasound

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Primary squamous cell carcinoma of the liver (PSCCL) is rare. PSCCL's lack of specific clinical manifestations and laboratory tests necessitate preoperative diagnosis via imaging examination. Conventional ultrasound (US) demonstrates a mass with mixed echogenicity, and contrast‐enhanced US shows a circular pattern of “fast forward, fast backward or slow backward, high enhancement.” Enhanced computed tomography (CT) showed enhancement in the center or edge of the lesion, and the density of the enhanced lesion was lower than that of the liver tissue in the same layer. Positron emission tomography‐CT demonstrates an inhomogeneous low‐density mass with increased 18F‐FDG metabolism. Magnetic resonance imaging shows low signal intensity on T1‐weighed images (T1WI) and high signal on T2‐weighed images (T2WI). By summarizing the imaging characteristics of PSCCL, this review aims to improve clinicians' understanding of PSCCL and its diagnosis.

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Section: Discussionmentioning

confidence: 99%

Section: Ct Characteristics Of Pscclmentioning

confidence: 99%

Section: Imaging Manifestationsmentioning

confidence: 99%

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Diagnostic value of imaging modalities in primary squamous cell carcinoma of the liver

Song

Shi

Zhang

et al. 2023

J of Clinical Ultrasound

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“…[1][2][3][4] To date, its pathogenesis remains unclear, and clinical recognition is difficult, relying only on pathology and immunohistochemistry to confirm the diagnosis. 1,[5][6][7] Only a few sporadic cases of primary squamous carcinoma of the liver have been reported, and their PET/CT findings have rarely been described. 8,9…”

Section: Figurementioning

confidence: 99%

Unusual Case of Primary Hepatic Squamous Carcinoma on 18F-FDG PET/CT

Li,

Liu,

Zhang

2023

Clin Nucl Med

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Primary hepatic squamous carcinoma is an extremely rare liver tumor type with high malignancy and poor prognosis. We present 18F-FDG PET/CT findings of primary squamous carcinoma of the liver in a 65-year-old man, who was admitted to the hospital with subxiphoid pain in the epigastric region radiating to the left lower back for 2 months. 18F-FDG PET/CT demonstrated a large heterogeneous mild enhancing mass in the left lobe of the liver, with intense circumferential 18F-FDG activity.

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Primary hepatic squamous cell carcinoma: case report and systematic review of the literature

Zhao,

Zhou,

Ding

et al. 2023

Front. Oncol.

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Primary hepatic squamous cell carcinoma (SCC) is extremely rare, and only a few dozen cases have been reported to date. It can barely be diagnosed before histopathological examination, which necessitates the exclusion of metastatic tumors. In this case, we present a 60-year-old female patient with no comorbidity. As laboratory tests and imaging examinations were not diagnostic, ultrasonography (US)-guided liver biopsy was performed and eventually revealed a definitive pathological diagnosis of hepatic SCC. After excluding metastasis, the diagnosis of primary hepatic SCC was established, and then chemotherapy and immunotherapy were performed. Additionally, a comprehensive literature search was conducted on primary hepatic SCC using PubMed, Google Scholar, and Web of Science, and a total of 53 articles were retrieved with a time range from 1972 to 2022. A critical analysis was then performed to evaluate previous literature focusing on the clinical characteristics, imaging features, treatments, and prognosis.

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Curative surgery for primary squamous cell carcinoma of the liver: a rare case study

Cited by 3 publications

References 30 publications

Diagnostic value of imaging modalities in primary squamous cell carcinoma of the liver

Diagnostic value of imaging modalities in primary squamous cell carcinoma of the liver

Unusual Case of Primary Hepatic Squamous Carcinoma on 18F-FDG PET/CT

Primary hepatic squamous cell carcinoma: case report and systematic review of the literature

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