Cumulative Radiation Dose and Cancer Risk Estimation in Common Diagnostic Radiology Procedures

Nikzad, Safoora; Pourkaveh, Maryam; Vesal, Naghi Jabbari; Gharekhanloo, Farideh

doi:10.5812/iranjradiol.60955

Cited by 7 publications

(10 citation statements)

References 20 publications

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“…In addition, when the pelvis is examined likewise, the total radiation dose can be increased (e.g., up to 15.5 mGy based on the data in Tables 2 and 3). These values are higher than accepted values from other studies in routine conditions [19][20][21][22][23][24][25][26][27] (Table 4). Also, Metaxas et al, 23 Although patient dose is less in plain radiography compared to other X-ray procedures, severely injured trauma patients may be exposed to several radiation fields leading to higher doses to the pelvis (see Table 3).…”

Section: Discussioncontrasting

confidence: 78%

Pelvic radiation dose measurement for trauma patients in multifield radiographic examinations: A phantom‐based TLD dosimetry study

Peiro

Chegeni

Danyaei

et al. 2023

Health Science Reports

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Background and Aims: Trauma patients often suffer from multiple injuries and require undergoing various radiography which is referred to as multifield radiographic examinations. Protective measures may be ignored for these examinations due to stressful emergency situations or patients' conditions. This study was conducted to evaluate the scattered doses received by the pelvis during different common multifield radiographic examinations with an emphasis on field size adjustment.Methods: A whole-body phantom, PBU-50, resembling the body mass, was used to carry out the common examinations for trauma patients (extremities, skull, chest, abdomen, pelvis, femur, and lumbar radiography), using a Pars Pad X-ray machine. To measure the primary entrance skin doses, three calibrated GR 200 thermoluminescence dosimeter (TLD) chips were placed in the central X-ray beam of scanned organs. Three TLDs were also placed on the pelvis symphysis pubis to measure the scattered dose received by the pelvis due to each carried-out radiography for standard and clinically used field sizes. A Harshaw 3500 TLD Reader was used to read the chips. TLD readouts (nano-Coulomb) were converted to dose (milli Gray [mGy]) using the predefined calibration curve. Results:The scattered doses to the pelvis due to scanning a single organ differed from 0.80 to 1.70, and 0.82 to 4.09 mGy for standard and clinically used field sizes, respectively. The scattered doses to the pelvis in multifield examinations varied from 0.80 to 8.43 and 0.82 to 13.6 mGy for standard and clinically used field sizes, respectively, depending on the number of scanned organs and their distances from the pelvis. Conclusions: Multiple and repeated radiographs combined with insufficient protective measures can increase the patient's dose. The findings indicate that the scattered doses received by the pelvis can exceed the reference values in multifield Health Sci. Rep.

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Section: Discussioncontrasting

confidence: 78%

Pelvic radiation dose measurement for trauma patients in multifield radiographic examinations: A phantom‐based TLD dosimetry study

Peiro

Chegeni

Danyaei

et al. 2023

Health Science Reports

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“…In contrast, CALDose-X software estimates the effective dose closer to the actual values (33) . It seems that one of the reasons for the high effective dose in this study compared to other ones was the difference between the dose calculation software and how to calculate the method with other studies (27,30,34,35) .…”

Section: Discussionmentioning

confidence: 74%

“…This confirms the need to continue such studies and to extend them to other X-ray diagnostic methods. Mashhad (36) 0.34 1.78 Kashan (37) 0.37 1.39 ChaharmahalBakhtiari (38) 0.7 6.92 Iran (39) 0.41 2.83 Esfahan (40) 0.74 6.84 Hamedan (34) 0.43 2.15 Mean ESD (in other studies in Iran) 0.49…”

Section: Discussionmentioning

confidence: 98%

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Entrance dose determination and effective dose calculation in chest and skull radiographies: an experimental and computational study

et al. 2021

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The use of ionizing radiation is popular as the most essential human-made source for medical diagnosis in most countries (1) . Medical images should provide enough information to make medical decisions with appropriate accuracy. In many cases, higher quality images are obtained using a high rate of radiation, which increases the dose of radiation received by patients (2) .The potential risk of losing diagnostic information due to a low radiation dose should be balanced

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“…TLDs that have minimum fading, high sensitivity, and high thermoluminescence are used exclusively for external dosimetry of the patient. More ever, due to their small size and proper structure, they do not cause any harm to the patient [21,22]. Assessment of The TLD tablets placed on the patient's body indicated that the absorbed radiation dose of patients is 7.72 ± 4.73 mSv.…”

Section: Absorbed Doses Measurementmentioning

confidence: 99%

Human exposure to low dose ionizing radiation affects miR-21 and miR-625 expression levels

et al. 2021

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Background Recently exposure to ionizing radiation driven by artificial radiation sources such as Medical X-rays and Nuclear medicine has increased hastily. Ionizing radiation-induced the DNA damage and activate the DNA damage response signaling pathways. The aim of this study was to evaluate the role of miR-21 and miR-625 in response to low-dose ionizing radiation. Materials and methodsIn this study, the blood sample of 38 volunteer patients who underwent Cardiac scans before and after 99m Tc-MIBI injection were used. The WBC of patients was used for RNA extraction and after cDNA synthesis by the poly-A method the expression level of miR-21 and miR-625 was evaluated by real-time PCR method. ResultsThe results of this study indicated that miR-21 and miR-625 were significantly upregulated under exposure to low-dose ionizing radiation. The expression level of these miRNAs was not significantly correlated with the age and BMI of patients. More ever the bioinformatics analysis indicated that SP1 was a common target of both miRNAs and had the highest degree between hub genes. Conclusion In summary miR-21 and miR-625 can contribute to the response to acute low dose ionizing radiation by targeting the SP1. However further studies should be carried out on the molecular mechanism of effects of miR-21 and miR-625 in response to low dose ionizing radiation by targeting the SP1.

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Cumulative Radiation Dose and Cancer Risk Estimation in Common Diagnostic Radiology Procedures

Cited by 7 publications

References 20 publications

Pelvic radiation dose measurement for trauma patients in multifield radiographic examinations: A phantom‐based TLD dosimetry study

Pelvic radiation dose measurement for trauma patients in multifield radiographic examinations: A phantom‐based TLD dosimetry study

Entrance dose determination and effective dose calculation in chest and skull radiographies: an experimental and computational study

Human exposure to low dose ionizing radiation affects miR-21 and miR-625 expression levels

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