CT-derived left ventricular global strain in aortic valve stenosis patients: A comparative analysis pre and post transcatheter aortic valve implantation

Marwan, Mohamed; Ammon, Fabian; Bittner, Daniel O.; Röther, Jens; Mekkhala, N.; Hell, Michaela M.; Schuhbaeck, Annika; Gitsioudis, Gitsios; Feyrer, R.; Schlundt, Christian; Achenbach, S.; Arnold, Martin

doi:10.1016/j.jcct.2018.01.010

Cited by 42 publications

(22 citation statements)

References 26 publications

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“…They noticed a significant decrease in GLS in symptomatic AS patients compared to the asymptomatic group (P value = 0.02). Besides, Marwan et al [10] found that global longitudinal strain was significantly lower after transcatheter aortic valve replacement operation compared to its baseline value. They included 25 patients with severe symptomatic aortic stenosis.…”

Section: Discussionmentioning

confidence: 99%

“…Recently, published studies have demonstrated an improvement in LV systolic function assessed by tissue Doppler and speckle tracking strain imaging in patients with severe AS and preserved EF after conventional surgical aortic valve replacement in a mid-term and long-term follow up [8] [9] [10]. Global Longitudinal strain (GLS) is considered as the most robust myocardial strain component [11].…”

Section: Introductionmentioning

confidence: 99%

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Assessment of Left Ventricular Function after Transcatheter Aortic Valve Implantation in Sever Aortic Stenosis: A Speckle Tracking Imaging Study

Saad¹,

Montaser²,

Emara³

et al. 2020

WJCD

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Background: Long standing aortic stenosis leads to elevated left ventricular (LV) pressure and as a result LV hypertrophy and myocardial fibrosis shall increase. The left ventricular ejection fraction (EF) usually remains adequately-preserved until advanced and late stages of aortic stenosis. But the preserved muscle of the LV is only limited to a portion of the entire myocardium. Speckle tracking echocardiography has proved its superiority to the standard two-dimensional echocardiography method in the detection of Left Ventricular (LV) function. Global Longitudinal strain (GLS) is considered as the most robust myocardial strain component. Objective: The aim of the study is to assess the early course of left ventricular reverse remodelling after Transcutaneous Aortic Valve Implantation (TAVI) in patients with symptomatic severe aortic valve stenosis. Methods: 50 patients with severe symptomatic valvular aortic stenosis undergoing TAVI as decided by the heart team after comprehensive discussion. Standard transthoracic echocardiography including Doppler analysis was performed. 2D speckle-tracking strain assessment of Global radial, circumferential and longitudinal strain at parasternal mid-ventricular short-axis view (at the level of papillary muscle) and from the apical long-axis, two-chamber and four-chamber views with a frame rate between 40 and 80 frames per second. Tracing of endocardial borders was done. Patients with significant coronary artery disease were fully revascularized by percutaneous coronary intervention prior to the study and the procedure. Results: 23 (46%) patients were males, while 27 (54%) were females. The patients' stratification according to comorbidities/associated risk factors re

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Assessment of Left Ventricular Function after Transcatheter Aortic Valve Implantation in Sever Aortic Stenosis: A Speckle Tracking Imaging Study

Saad¹,

Montaser²,

Emara³

et al. 2020

WJCD

View full text Add to dashboard Cite

show abstract

“…CTA-derived assessment of strain has emerged as a valuable method for the assessment of cardiac function, and it shows close correlations with both echocardiography and CMR [10][11][12][13]. The usefulness of CT-derived assessments of left ventricular strain in severe aortic stenosis [11], aortic valve stenosis [14], adult congenital heart disease [15] and myocardial infarction [16] has been reported. However, to the best of our knowledge, there have been no studies on CAD.…”

Section: Introductionmentioning

confidence: 99%

Assessment of Regional Left Ventricular Myocardial Strain in Patients with Left Anterior Descending Coronary Stenosis Using Computed Tomography Feature Tracking

Han

Cao

et al. 2020

Preprint

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Background Computed Tomography feature tracking (CT-FT) has emerged as a valuable method for the assessment of cardiac function. However, there have been no study about the usefulness of CT-derived assessments of left ventricular strain on coronary artery disease (CAD). Our aim was to evaluate the regional left ventricular (LV) systolic deformation in patients with left anterior descending coronary (LAD) stenosis using CT-FT. Methods Seventy-six patients with LAD stenosis were enrolled. The patients were divided into four groups according to the percentage of LAD stenosis: ≤25% was defined as group I (24 patients), 26–49% as group II (17 patients), 50–74% as group III (21 patients), and ≥ 75% as group IV (14 patients).Thirty-two sex- and age-matched normal subjects were included as controls. Results No intergroup differences were found between groups I-IV and the controls in terms of the left ventricular ejection fraction, end-diastolic volume and end-systolic volume. However, the longitudinal strain (LS) of the LAD territory was significantly reduced in groups I-IV compared with the controls (-20.8% and − 18.5% and − 18.6% and − 17.0% vs -23.7%, respectively). The circumferential strain (CS) of the LAD territory was significantly reduced in groups III and IV compared with the controls and groups I and II (-22.4% and − 22.2% vs -25.4% and − 24.1% and − 25.3%, respectively). Compared with non-LAD territory, groups II-IV had significantly increased LS (-19.9% vs -21%; -18.6% vs -21.9%; -16.4% vs -20.1%). The severity of LAD stenosis had a positive correlation with the LS of the LAD territory (r = 0.438, p = 0.002). Conclusion CT‑FT can detect decreasing LV systolic function in patients with LAD stenosis. With the increasing severity of LAD stenosis, the LV regional systolic deformation of the LAD territory was reduced.

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“…CTA-derived assessment of strain has emerged as a valuable method for the assessment of cardiac function, and it shows close correlations with both echocardiography and CMR [ 10 – 13 ]. The usefulness of CT-derived assessments of left ventricular strain in severe aortic stenosis [ 11 ], aortic valve stenosis [ 14 ], adult congenital heart disease [ 15 ] and MI [ 16 ] has been reported. However, to the best of our knowledge, there have been no studies on CAD.…”

Section: Introductionmentioning

confidence: 99%

Assessment of regional left ventricular myocardial strain in patients with left anterior descending coronary stenosis using computed tomography feature tracking

Han

Cao

et al. 2020

BMC Cardiovasc Disord

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Background: Computed tomography feature tracking (CT-FT) has emerged as a valuable method for the assessment of cardiac function. However, no studies have investigated the usefulness of CT-derived assessments of left ventricular (LV) strain in coronary artery disease (CAD). Our aim was to evaluate regional LV systolic deformation in patients with left anterior descending coronary artery (LAD) stenosis using CT-FT. Methods: Seventy-six patients with LAD stenosis were enrolled. The patients were divided into four groups according to the percentage of LAD stenosis: ≤25% was defined as group I (24 patients), 26 to 49% as group II (17 patients), 50 to 74% as group III (21 patients), and ≥ 75% as group IV (14 patients). Thirty-two sex-and age-matched healthy subjects were included as controls. Results: No intergroup differences were found between groups I-IV and the controls in terms of the left ventricular ejection fraction, end-diastolic volume and end-systolic volume. However, the longitudinal strain (LS) of the LAD territory was significantly reduced in groups I-IV compared with the controls (− 20.8, − 18.6%, − 18.6%, and − 17.0% vs − 23.7%, respectively). The circumferential strain (CS) of the LAD territory was significantly reduced in groups III and IV compared with the controls and groups I and II (− 22.4% and − 22.1% vs − 25.4, − 24.1%, and − 25.3%, respectively). Compared with the non-LAD territory, the LAD territory in groups II-IV showed significantly increased LS (− 18.6% vs − 21.9%, p = 0.07; − 18.6% vs − 21.9%, p = 0.024; − 17.5% vs − 20%, p = 0.032, respectively). The severity of LAD stenosis was positively correlated with the LS of the LAD territory (r = 0.438, p = 0.002). Conclusion: CT-FT can detect decreasing LV systolic function in patients with LAD stenosis. LV regional systolic deformation of the LAD territory was reduced with increasing LAD stenosis severity.

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CT-derived left ventricular global strain in aortic valve stenosis patients: A comparative analysis pre and post transcatheter aortic valve implantation

Cited by 42 publications

References 26 publications

Assessment of Left Ventricular Function after Transcatheter Aortic Valve Implantation in Sever Aortic Stenosis: A Speckle Tracking Imaging Study

Assessment of Left Ventricular Function after Transcatheter Aortic Valve Implantation in Sever Aortic Stenosis: A Speckle Tracking Imaging Study

Assessment of Regional Left Ventricular Myocardial Strain in Patients with Left Anterior Descending Coronary Stenosis Using Computed Tomography Feature Tracking

Assessment of regional left ventricular myocardial strain in patients with left anterior descending coronary stenosis using computed tomography feature tracking

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