CT colonography at low tube potential: using iterative reconstruction to decrease noise

Chang, Kevin J.; Heisler, M.A.; Mahesh, Mahadevappa; Baird, Grayson L.; Mayo-Smith, William W.

doi:10.1016/j.crad.2015.05.005

Cited by 5 publications

(2 citation statements)

References 42 publications

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“…The increase in the CNR at low tube potential therefore allows the tube current to be set lower while maintaining perceived image quality, with a consequent reduction in the radiation dose (32,33). The availability of more-efficient detectors and iterative reconstruction techniques aids in denoising examinations performed with lower tube potential, augmenting the potential dose savings (34,35).…”

Section: Low-kilovolt Imaging Technical Principlesmentioning

confidence: 99%

Advanced CT Techniques for Decreasing Radiation Dose, Reducing Sedation Requirements, and Optimizing Image Quality in Children

et al. 2019

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Section: Low-kilovolt Imaging Technical Principlesmentioning

confidence: 99%

Advanced CT Techniques for Decreasing Radiation Dose, Reducing Sedation Requirements, and Optimizing Image Quality in Children

et al. 2019

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“…Contrast medium with a low concentration will result in a reduction of the iodine concentration in blood under the same infusion protocol and might even lower the CT attenuation, while the application of lower tube voltage may produce a higher CT attenuation value for iodinated structures and thus provide an opportunity to use low iodine concentration. Though a drawback of reduced tube voltage is that the noise of CTA images might increase and potentially compromise the diagnostic accuracy, the recent introduction of iterative reconstruction algorithm can dramatically reduce image noise and improve image quality (18,19). According to the Society of Cardiovascular Computed Tomography (SCCT) guidelines on radiation dose and dose-optimization strategies in cardiovascular CT, a tube voltage of 80-100 kVp is suitable for individuals weighing 90 kg or with a BMI 30 kg/m 2 (20).…”

Section: Discussionmentioning

confidence: 99%

An open label, prospective, multicenter, non-interventional study of iodixanol 270 mg I/mL for use in individuals undergoing computed tomography angiography in real-world clinical practice

Lü²,

et al. 2018

Acta Radiol

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Background Concern about radiation exposure is leading to an increasing interest in low-concentration contrast medium administration. Purpose To evaluate the image quality and safety profile after administration of iodixanol 270 mg I/mL at 100-kVp tube voltage with iterative reconstruction in subjects undergoing computed tomography angiography (CTA). Material and Methods Patients who completed CTA examination using iodixanol 270 mg I/mL and 100-kVp tube voltage along with iterative reconstruction for coronary, aortic, head and neck, renal, or pulmonary arteries were included. Image quality was qualitatively and quantitatively evaluated. Incidence of adverse events (AEs) and adverse drug reactions (ADRs) within seven days and radiation dose were also analyzed. Results A total of 4513 individuals in 42 centers in China were enrolled, among which 4367 were included in efficacy analysis. The mean image quality score was 4.8 ± 0.45 across all arteries (all above 4.6) and 99.7% of the individuals' images were classified as evaluable. The CT attenuation, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) in the regions of interest (ROIs) were 431.79 ± 99.018, 18.29 ± 11.947, and 28.21 ± 19.535 HU, respectively. Of all the participants, 68 (1.5%) and 65 (1.4%) experienced AEs and ADRs, respectively. No serious AEs or AEs leading to discontinuation occurred. The average effective radiation dose was 3.13 ± 2.550 mSv. Conclusion Iodixanol 270 mg I/mL in combination with 100-kVp tube voltage and iterative reconstruction could be safely applied in CTA and yield high-quality and evaluable images with reduced radiation dose.

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CTC technique: methods to ensure an optimal exam

Chang

Kim

2018

Abdom Radiol

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CT colonography (CTC) has demonstrated equivalent accuracy to optical colonoscopy in the detection of clinically relevant polyps and tumors but this is only possible when technique is optimized. The two most important features of a high-quality CTC are a well-prepared colon and a distended colon. This article will discuss the dietary, bowel preparation, and fecal/fluid tagging options to best prepare the colon. Strategies to optimally distend the colon will also be discussed. CT scan techniques including patient positioning and radiation dose optimization will be reviewed. With proper technique which includes sufficient bowel preparation, fecal/fluid tagging, bowel distension, and optimized scan technique, high-quality CTC examinations should become more feasible, easier to interpret, and more consistently reproducible leading to increased utilization and increased referrals.

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CT colonography at low tube potential: using iterative reconstruction to decrease noise

Cited by 5 publications

References 42 publications

Advanced CT Techniques for Decreasing Radiation Dose, Reducing Sedation Requirements, and Optimizing Image Quality in Children

Advanced CT Techniques for Decreasing Radiation Dose, Reducing Sedation Requirements, and Optimizing Image Quality in Children

An open label, prospective, multicenter, non-interventional study of iodixanol 270 mg I/mL for use in individuals undergoing computed tomography angiography in real-world clinical practice

CTC technique: methods to ensure an optimal exam

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