CT-based postimplant dosimetry of prostate brachytherapy: comparison of 1-mm and 5-mm section CT

Tanaka, Osamu; Hayashi, Shinya; Kanematsu, Masayuki; Nakano, Masahiro; Maeda, Sunaho; Deguchi, Takashi; Hoshi, Hiroaki

doi:10.1007/s11604-006-0096-0

Cited by 2 publications

(1 citation statement)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For patients with disease confined to the gland, there has been a renewed interest in brachytherapy (4-6) following the advent of ultrasound image-guided seed implants (7-9) and more recently computerized tomography (CT)-guided (10, 11) and magnetic resonance (MR)-guided (12, 13) implants. In such a procedure, on the order of 100 radioactive sources are permanently placed within the prostate gland in such a manner as to deliver the prescribed dose to the prostate.…”

Section: Introductionmentioning

confidence: 99%

A Magnetic Resonance-based Seed Localization Method for I-125 Prostate Implants

et al. 2007

View full text Add to dashboard Cite

This study was performed to develop and evaluate a semi-automatic seed localization algorithm from magnetic resonance (MR) images for interstitial prostate brachytherapy. The computerized tomography (CT) and MR images (3 mm-slice thickness) of six patients who had received real-time MR imaging-guided interstitial prostate brachytherapy were obtained. An automatic seed localization method was performed on CT images to obtain seed coordinates, and an algorithm for seed localization from MR images of the prostate was developed and tested. The resultant seed distributions from MR images were then compared to CT-derived distribution by matching the same seeds and calculating percent volume receiving 100% of the prescribed dose and the extent of the volume in 3-dimensions. The semiautomatic seed localization method made it possible to extract more than 90% of the seeds with either less than 8% of noises or 3% of missing seeds. The mean volume difference obtained from CT and MR receiving 100% of the prescribed dose was less than 3%. The maximum extent of the volume receiving the prescribed dose were 0.3, 0.6, and 0.2 cm in x, y, and z directions, respectively. These results indicate that the algorithm is very useful in identifying seeds from MR image for post-implant dosimety.

show abstract