A Magnetic Resonance-based Seed Localization Method for I-125 Prostate Implants

Lee, Rena J; Suh, Hyun Suk; Lee, Kyung Ja; Lim, Soome; Kim, Yookyung; Kim, Sungkyu; Choi, Jin-Ho

doi:10.3346/jkms.2007.22.s.s129

Cited by 5 publications

(1 citation statement)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Meanwhile, in addition to external radiotherapy, innovations in brachytherapy, commonly used to treat prostate cancer, have made it possible to insert radioactive isotopes more accurately and more precisely by incorporating transrectal ultrasound images. Recently, attempts to fuse MRI images with ultrasound images or CT for initial treatment or post-implant dosimetry planning have been made ( 15 16 ). In the case of brachytherapy for uterine cervical cancer or other high dose rate brachytherapy, 3D brachytherapy plans using CT or MRI images have been widely applied, and finer and safer treatments are being implemented accordingly ( 17 ).…”

Section: Decreases Of the Effects Of Radiation On Normal Tissues Follmentioning

confidence: 99%

Evolving Clinical Cancer Radiotherapy: Concerns Regarding Normal Tissue Protection and Quality Assurance

Choi

Cho

2016

J Korean Med Sci

View full text Add to dashboard Cite

Radiotherapy, which is one of three major cancer treatment methods in modern medicine, has continued to develop for a long period, more than a century. The development of radiotherapy means allowing the administration of higher doses to tumors to improve tumor control rates while minimizing the radiation doses absorbed by surrounding normal tissues through which radiation passes for administration to tumors, thereby reducing or removing the incidence of side effects. Such development of radiotherapy was accomplished by the development of clinical radiation oncology, the development of computers and machine engineering, the introduction of cutting-edge imaging technology, a deepened understanding of biological studies on the effects of radiation on human bodies, and the development of quality assurance (QA) programs in medical physics. The development of radiotherapy over the last two decades has been quite dazzling. Due to continuous improvements in cancer treatment, the average five-year survival rate of cancer patients has been close to 70%. The increases in cancer patients’ complete cure rates and survival periods are making patients’ quality of life during or after treatment a vitally important issue. Radiotherapy is implemented in approximately 1/3 to 2/3s of all cancer patients; and has improved the quality of life of cancer patients in the present age. Over the last century, as a noninvasive treatment, radiotherapy has unceasingly enhanced complete tumor cure rates and the side effects of radiotherapy have been gradually decreasing, resulting in a tremendous improvement in the quality of life of cancer patients.

show abstract

Section: Decreases Of the Effects Of Radiation On Normal Tissues Follmentioning

confidence: 99%

Evolving Clinical Cancer Radiotherapy: Concerns Regarding Normal Tissue Protection and Quality Assurance

Choi

Cho

2016

J Korean Med Sci

View full text Add to dashboard Cite

show abstract

Automatic seed localization of iodine brachytherapy implants from CT images

Lin

Jin

et al. 2014

Australas Phys Eng Sci Med

View full text Add to dashboard Cite

Radioactive seed implantation has emerged as an effective treatment modality where small radioactive seeds are implanted into the target organ to eradicate the cancer by emitting radiation. Precise seeds localization can indicate whether those seeds deliver sufficient doses of radiation. However, it is challenging and laborious to identify all seeds manually in a short time. Therefore, our purpose in this study was to develop an automatic technique for identifying implanted seeds on any parts of body. The algorithm relies on a 3D adaptive median filter to remove bone structure; white top-hat transform to extract seeds-like objects and further seed classification analysis based on size, shape and their connection etc. Preliminary results on ten patients and seven simulated data show that this approach to be effective and accurate. It resulted in a 96.9 % detection rate with a corresponding 4.7 % false-positive rate for clinical data; a 98.5 % detection rate with a corresponding 4.1 % false-positive rate for the simulated data; and sub-millimeter accuracy for both data sets. This method can achieve robust and accurate seed segmentation through the proposed workflow.

show abstract