CT and MRI appearances of a thoracic chordoma

Murphy, Jennifer; Wallis, F.; Toland, J.; Toner, Mary; Wilson, Graham

doi:10.1007/s003300050611

Cited by 44 publications

(16 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These septa have been reported in 70% of chordomas and are characteristic features of chordomas. 24 However, we only found these in 2 of 5 patients. Four cases of chordoma demonstrated mild to moderate enhancement after contrast material injection.…”

Section: Discussionmentioning

confidence: 59%

Primary Chordoma in the Nasal Cavity and Nasopharynx: CT and MR Imaging Findings

Zhang¹,

Yang²,

Wang³

et al. 2009

AJNR Am J Neuroradiol

View full text Add to dashboard Cite

BACKGROUND AND PURPOSE:Primary chordoma in the nasal cavity and nasopharynx is an extremely rare tumor in the extraosseous axial skeleton. Unlike intracranial chordomas, lesions in these sites primarily present as a soft tissue mass without involvement of the skull base bone (clivus), so the preoperative diagnosis of the tumor is possibly difficult. Here, we reviewed the imaging features of 5 cases of chordomas in the nasal cavity and nasopharynx that resulted in successful diagnosis and differential diagnosis of this rare tumor.

show abstract

Section: Discussionmentioning

confidence: 59%

Primary Chordoma in the Nasal Cavity and Nasopharynx: CT and MR Imaging Findings

Zhang¹,

Yang²,

Wang³

et al. 2009

AJNR Am J Neuroradiol

View full text Add to dashboard Cite

show abstract

“…The initial symptoms of thoracic chordoma are subtle and nonspecific. Usually, symptoms are seen with spinal cord compression or thoracic viscera compression (1,9,11,15). The second tumor of our case was at the thoracal region, T3 level.…”

Section: Discussionmentioning

confidence: 67%

A case of chordoma invading multiple neuroaxial bones:report of ten years follow up

Aydın¹,

Sasani²,

Öktenoğlu³

et al. 2012

Turkish Neurosurgery

View full text Add to dashboard Cite

AIm: Chordoma is a rare, slow-growing primary malignant tumor of the axial skeleton, arising from the embryonic cells of primitive notochord. Chordomas may arise at different sites of the vertebral column simultaneously or more probably they may metastasise along the neural axis insidiously. Recurrence despite radical surgery and following adjuvant therapy is possible. mAterIAl and methOds:A 46-year-old female patient presented weakness and numbness of the lower extremities. She was operated for clivus chordoma five years ago at another institute.results: First the patient underwent surgery for resection of the tumor at the cervical region. a second surgery was performed to resect tumor on the foramen magnum and at the C1 level. Histologic examination of the removed vertebra confirmed the diagnosis of chordoma involving the vertebral body. Radiotherapy was administered after the second surgery. Follow-up neurological and radiological examinations revealed no abnormal neurological symptoms 2,5 years after second surgery. There were no distant organ metastases.COnClusIOn: A patient with diagnosed chordoma of the spine must be investigated with MRI of other regions of the neuraxis to exclude second or even third source of chordoma metastases. In metastatic chordoma cases, radical or gross total resection should be performed for each lesion but if complete surgical resections are impossible, preoperative or postoperative radiation therapy should be planned to improve life expectancy.KeywOrds: Chordoma, Cervical tumor, Thoracal tumor, Spinal tumor, Metastasis ÖZ AmAÇ: Kordoma, omurganın ender rastlanan, yavaş ilerleyen malign karakterli bir tümörüdür. Primitif notokordun embryo hücrelerinden köken alır. Omurganın farklı bölgelerinde, birbirinden bağımsız kordoma odakları eş zamanlı olarak gelişmeye başlayabilir. Fakat daha sıklıkla, birinci tümör odağından kaynaklanan metastatik kordoma lezyonları tüm nöral aks boyunca yayılabilir. Radikal cerrahiye ve ek onkolojik tedaviye rağmen rekürens sık görülür. yÖntem ve GereÇler: Bu sunumda tartışılan 46 yaşındaki kadın hasta, bacaklarında kuvvet ve his kaybı şikayetiyle kliniğimize başvurmuştur. Hasta, beş yıl önce, ayrı bir merkezde klivus kordoması tanısıyla opere edilmiştir.BulGulAr: Hasta öncelikle servikal bölgedeki tümör için opere edilmiştir. İkinci seansta foramen magnum ve C1 seviyesindeki tümör çıkarılmıştır. Patolojik inceleme sonucunda, omurga cismini tutan kordoma lezyonu tanısı konmuştur. İkinci cerrahi seansından sonra hasta radyoterapiye yönlendirilmiştir. Bu tedaviden ikibuçuk yıl sonra yapılan değerlendirmede, hastanın nörolojik muayenesinde progresyon gözlenmemiştir.sOnuÇ: Omurganın herhangi bir lokalizasyonunda kordoma tanısı konulan bir hastada, tüm spinal bölge manyetik rezonans görüntüleme (MRG) tetkiki ile incelenmelidir. Bu hastalarda birden fazla kordoma odağına rastlanabilir. Birden fazla odak tespit edilmesi durumunda, her ayrı tümör odağı için rezeksiyon planlanmalıdır. Total rezeksiyonun mümkün olmaması durumunda, yaşam süresini uzatmak...

show abstract

“…En bloc spondylectomy and even intralesional resection however are not devoid of complications. Of the 15 reported cases that detail outcomes, 2 died from perioperative complications [13,15]. As always, the balance between treatment morbidity and long-term disease control must be carefully discussed with the patient.…”

Section: Discussionmentioning

confidence: 99%

Chordoma of the thoracic spine in an 89-year-old

Fontes

O’Toole

2011

Eur Spine J

View full text Add to dashboard Cite

Study design Case report and literature review. Objective Report the highly unusual presentation of thoracic spine chordoma in an 89-year-old and review existing literature as it impacts treatment in the elderly. Summary of background data Chordomas are infrequent tumors of the spine that commonly present during midadulthood at the spheno-occipital or sacrococcygeal junctions. The mobile spine is affected in 10-15% of cases but chordomas are extremely rare in the thoracic spine. Chordoma rarely enters the differential diagnosis of spinal tumors in elderly patients, for whom metastases and multiple myeloma are by far the most common. Methods A case report is detailed of an 89-year-old male presenting with incapacitating pain and early signs of thoracic myelopathy. A lytic, expanding lesion of the T10 vertebral body with epidural spinal cord compression was identified. In the absence of evidence of other primary tumor, a CT-guided needle biopsy revealed chordoma. A literature review of reported thoracic spine chordomas was also performed. Results An intralesional posterolateral resection and reconstruction was performed with good results and no recurrence at 13 months' follow-up. 30 reports of thoracic spine chordomas were identified in the literature since 1902. Mean age of presentation at 35.7 years is earlier than for most chordomas. The oldest previously reported patient was 68-year-old. Neurological impairment at presentation is rare with the usual presenting symptom being pain.Response to radiation and chemotherapy is limited. 5-year survival rates range from 50 to 60%. Conclusion Chordoma is a highly uncommon epidural neoplasm of the thoracic spine and is vanishingly rare in elderly patients. This report documents the oldest reported patient with thoracic spine chordoma at 89-year-old. Their locally aggressive behavior typically prompts consideration of aggressive surgical resection. When tailored to the individual patient, such procedures are feasible without excessive morbidity even in elderly patients.

show abstract

CT and MRI appearances of a thoracic chordoma

Cited by 44 publications

References 8 publications

Primary Chordoma in the Nasal Cavity and Nasopharynx: CT and MR Imaging Findings

Primary Chordoma in the Nasal Cavity and Nasopharynx: CT and MR Imaging Findings

A case of chordoma invading multiple neuroaxial bones:report of ten years follow up

Chordoma of the thoracic spine in an 89-year-old

Contact Info

Product

Resources

About