Crystal structure of 1,3-bis[(E)-benzylideneamino]propan-2-ol

Abstract

In the title compound, C 17 H 18 N 2 O, the central carbon atom with the OH substituent and one of the (E)-benzylideneamino substituents are disordered over two sets of sites with occupancies of 0.851 (4) and 0.149 (4). The relative positions of the two disorder components is equivalent to a rotation of approximately 60 about the C-N single bond. In the crystal, the molecules are held together by O-HÁ Á ÁN hydrogen bonds, forming simple C(5) chains along the b-axis direction. In addition, pairs of the chains are further aggregated by weak C-HÁ Á Á interactions.

1,3-Bis{(E)-[4-(dimethylamino)benzylidene]amino}propan-2-ol: chain structure formation via an O—H...N hydrogen bond

“…Schiff bases play important roles in the development of coordination chemistry related to catalysis, enzymatic reactions, and supramolecular architectures. Crystal structures of Schiff bases derived from substituted benzaldehydes and 1,3-diaminopropan-2-ol have been reported earlier Azam, Hussain et al, 2012;Rivera et al, 2016bRivera et al, , 2017Elmali, 2000). The title compound, (I), acts as an important raw material for the synthesis of Schiff base complexes.…”

1,3-Bis[(E)-(3-bromobenzylidene)amino]propan-2-ol

“…Biologically active nitrogen of (>C=N-) upon coordination with a transition metal center lead to complexes with improved pharmacological and physicochemical properties [7][8][9][10][11][12][13][14][15]. Despite the large number of the prepared Schiff base ligands together with their complexes, there remains an urgent need for novel ligands with new applications and properties.…”

“…The presence of the unsaturated nitrogen atom (>C=N) together with its lone pair of electrons makes the Schiff base an attractive e-donor ligand [11][12][13][14]. Such donation ability plays a critical role in the complexation with several metal ions centers [10][11][12][13][14][15][16][17].…”

“…Such compounds have been used as dyes and pigments, corrosion inhibitors, thermo-stable materials, and catalysts [3][4][5][6] and in medical applications as antifungal, anticancer, and antibacterial agents [7][8][9][10][11][12].…”

“…Such donation ability plays a critical role in the complexation with several metal ions centers [10][11][12][13][14][15][16][17].…”