T his contribution was prompted in response to the recent Perspective by Desiraju and Nangia (hereafter DN). 1 The somewhat unconventional format used here is consistent with scientific discourse in general and the nature of an Editorial comment. Following an initial exchange of views the four authors opted on adopting a format historically employed in written discourse−namely, presenting the views of various commentators together in the same textual offering. Likewise, each of the authors of this contribution wishes to comment individually on the DN Perspective, but we wish to contain the comments in one publication to be read, considered, and cited together rather than individually. As a result, each comment is self-contained, with its own text and references cited at the end.Dario Braga and Fabrizia Grepioni Comment. In a recent editorial Desiraju and Nangia address the question of the limited use of the term "crystal engineering" in the regulatory and patent literature of pharmaceutical solid forms.Conversely, the same term appears to be very well rooted in the scientific literature. This is witnessed, inter alia, by the existence of successful journals devoted to crystal engineering published by two of the most important learned chemical societies in the world, the American Chemical Society (this journal) and the Royal Society of Chemistry (CrystEngComm).Since both industrial and academic researchers interested in solid formulations of drugs (but also of pigments, nutraceuticals, agrochemicals, etc.) publish papers and file patents, the lower popularity of the term crystal engineering in intellectual property with respect to the scientific literature must originate from the different requirements of the two types of dissemination tools.Let us see first how the ACS and RSC crystal engineering journals define their scopes: (1) "The aim of Crystal Growth & Design is to stimulate crossfertilization of knowledge among scientists and engineers working in the fields of crystal growth, crystal engineering, and the industrial application of crystalline materials. [...] Synergistic approaches originating from different disciplines and technologies and integrating the fields of crystal growth, crystal engineering, intermolecular interactions, and industrial application are encouraged [...]". 2 (2) "CrystEngComm is the journal for innovative research covering all aspects of crystal engineering, the design, including synthesis of crystals and crystal growth, synthesis and evaluation of solid-state materials with desired properties[...]". 3 Unsurprisingly, these journals, as well as many others published by the same and other publishers, contain many explicit references to "crystal engineering". Figure 1 shows the occurrence of papers containing the terms "crystal engineering" in the title, abstract, and keywords and the number of citations of such papers over time (source WoS 4 ). Besides there is, of course, a very large occurrence of terms referring to crystal forms, e.g., solvates, polymorphs, co-crystals, ionic co-...