Crystal feature and spectral characterization of Zn(II) complexes containing Schiff base of Acylpyrazolone ligand with antimalarial action

Shaikh, Irfan; Travadi, Maitrey; Jadeja, R.N.; Butcher, Ray J.; Pandya, Jignesh H.

doi:10.1016/j.jics.2022.100428

Cited by 15 publications

(7 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…CT mainly comes from the essential oil of lemon grass and has vigorous antibacterial activity: it was used for comparison against V. parahaemolyticus (MIC = 1024 µg/mL) along with CS-CT (MIC = 256 µg/mL) and ciprofloxacin (MIC = 4 µg/mL). (42), and their antifungal activity evaluation against Aspergillus flavus, A. niger, Penicillim chryogenum, Fusarium oxysporum, and Trichoderma viride, by disc diffusion method. Amphotericin-B was used as the standard drug (IZD = 22, 26, 20, 22, and 26 mm, respectively).…”

Section: Chitosan Sbs Complexes As Antimicrobialsmentioning

confidence: 99%

“…The highly stable complexes formed by SBs with transition metals often lead to compounds with strongly enhanced activities in inorganic [22,23] and bioinorganic chemistry [24], materials science [25], and pharmacology for biomedical applications [26][27][28][29][30]. The most described biological activities regarding the SBs complexes are antitumoral [31][32][33][34][35], antioxidant [36,37], antidiabetic [38][39][40][41], antimalarial [42], antiarthritic [43], antimicrobial [44][45][46][47][48], neuroprotective, catalase-like and catecholase-like enzymatic [49,50], and DNA-binding [51,52]. Recently, Aggarwal et al (2022) [53] underlined the potential applicability of some SBs and their metal complexes for the treatment of COVID-19 [54], which may represent valid alternatives to the classic treatments for this disease [55,56].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Metal Complexes with Schiff Bases as Antimicrobials and Catalysts

Iacopetta,

Ceramella,

Catalano

et al. 2023

Inorganics

View full text Add to dashboard Cite

Complexes of Schiff bases (SBs) with metals are promising compounds exhibiting a broad range of applications, such as catalysts, polymers, dyes, and several biological activities, including antimicrobial, anticancer, antioxidant, antimalarial, analgesic, antiviral, antipyretic, and antidiabetic actions. Considering the crisis that the whole world is now facing against antimicrobial-resistant bacteria, in the present review, we chose to focus on the activity of SBs as antimicrobials, particularly underlying the most recent studies in this field. Finally, some interesting catalytic applications recently described for metal complexes with SBs have also been discussed.

show abstract

Section: Chitosan Sbs Complexes As Antimicrobialsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Metal Complexes with Schiff Bases as Antimicrobials and Catalysts

Iacopetta,

Ceramella,

Catalano

et al. 2023

Inorganics

View full text Add to dashboard Cite

show abstract

“…Based on acylpyrazolones and benzhydrazide, the novel ligand 46 was found to work well for the detection of Zn 2+ ions by Shaikh et al (Figure 14 ). 92 The working of the ligands was investigated with various spectroscopic techniques. This ligand also showed anti-malarial activity.…”

Section: Schiff Base Probes For Zn 2+ Recognitionmentioning

confidence: 99%

“…All rights reserved. With the help of acylpyrazolones and benzhydrazide synthesized, the novel ligands 46 (Figure 14) work Well to detect the Zn 2+ ion by Shaikh et al [92] the working of ligands investigated with the help of various spectroscopic techniques. This ligand shows anti-malarial activity.…”

mentioning

confidence: 99%

Recent Developments in the Detection of Zn2+ Ions Using Schiff Base Probes

Singh,

Pani,

Kumar

et al. 2023

SynOpen

View full text Add to dashboard Cite

In the past few decades, zinc has received great attention towards the scientific community due to its supreme importance in living organisms. Zinc is a trace element that is vitally important to all living organisms and it plays an important role in the immune system, wound healing, growth and division. Therefore, the development and advancement of simple, efficient, selective and inexpensive chemosensors for the determination of Zn2+ is of paramount prerequisite. Chemosensors have unique properties that are used for the determination of several metal ions specifically and selectively. This review summarizes the Schiff base chemosensors designed and synthesized by several research groups from the year 2018. The interaction of these probes with zinc metal ions has also been discussed briefly in this review. Furthermore, the comparison of detection limits of these probes demonstrated that the Schiff base probe 34 possessing two benzothiazole moieties exhibits the lowest detection limit (0.00028 µM) indicating it to be the lead compound in the determination of Zn2+ ions in near future.

show abstract

“…Shaikh et al, (2022) [ 74 ] recently studied two SBs zinc complexes with the structure -C=N-N- for their antimalarial activities against P. falciparum using the MTT assay. The complex Zn(BZ-PCBPMP) 2 ( 20 ) with ( Z )- N ’-((4-chlorophenyl)-(1-phenyl)-3-methyl-5-oxo-1,5-dihydro-4 H -pyrazol-4-ylidene) methyl) benzohydrazide) was the most active compared with the standards, quinine (MIC = 0.8 μmol/L) and chloroquine showing (MIC = 0.09 μmol/L).…”

Section: Mononuclear Sbs Complexesmentioning

confidence: 99%

Metal Complexes with Schiff Bases: Data Collection and Recent Studies on Biological Activities

Sinicropi

Ceramella

Iacopetta

et al. 2022

IJMS

View full text Add to dashboard Cite

Metal complexes play a crucial role in pharmaceutical sciences owing to their wide and significant activities. Schiff bases (SBs) are multifaceted pharmacophores capable of forming chelating complexes with various metals in different oxidation states. Complexes with SBs are extensively studied for their numerous advantages, including low cost and simple synthetic strategies. They have been reported to possess a variety of biological activities, including antimicrobial, anticancer, antioxidant, antimalarial, analgesic, antiviral, antipyretic, and antidiabetic ones. This review summarizes the most recent studies on the antimicrobial and antiproliferative activities of SBs-metal complexes. Moreover, recent studies regarding mononuclear and binuclear complexes with SBs are described, including antioxidant, antidiabetic, antimalarial, antileishmanial, anti-Alzheimer, and catecholase activities.

show abstract

Crystal feature and spectral characterization of Zn(II) complexes containing Schiff base of Acylpyrazolone ligand with antimalarial action

Cited by 15 publications

References 41 publications

Metal Complexes with Schiff Bases as Antimicrobials and Catalysts

Metal Complexes with Schiff Bases as Antimicrobials and Catalysts

Recent Developments in the Detection of Zn2+ Ions Using Schiff Base Probes

Metal Complexes with Schiff Bases: Data Collection and Recent Studies on Biological Activities

Contact Info

Product

Resources

About