“…4 In the quinuclidine ring system the C-N distances [N(1)-C(15) 1.462(2), N(1)-C(18) 1.473 (3) and N(1)-C(20) 1.476( 3) Å] are slightly shorter compared with cinchonine alkaloid. 5 No significant difference was found in the bond angles [C(18) -N(1)-C(20) 108.84(16)°, C(15)-N(1)-C(18) 108.25(15) (2)° and C(15)-N(1)-C(20) 108.36(16)…”
Quinuclidin-3-yl 2-cyclopentyl-2-hydroxy-2-phenylacetate, a more effective the muscarinic receptor antagonist, was synthesised and its crystal structure was first elucidated by X-ray crystallography.
“…4 In the quinuclidine ring system the C-N distances [N(1)-C(15) 1.462(2), N(1)-C(18) 1.473 (3) and N(1)-C(20) 1.476( 3) Å] are slightly shorter compared with cinchonine alkaloid. 5 No significant difference was found in the bond angles [C(18) -N(1)-C(20) 108.84(16)°, C(15)-N(1)-C(18) 108.25(15) (2)° and C(15)-N(1)-C(20) 108.36(16)…”
Quinuclidin-3-yl 2-cyclopentyl-2-hydroxy-2-phenylacetate, a more effective the muscarinic receptor antagonist, was synthesised and its crystal structure was first elucidated by X-ray crystallography.
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