Crystal and molecular structure of bis(.mu.-(1-methyluracilato-N3,O4))-bis(cis-diammineplatinum(II)) dinitrate trihydrate, [(NH3)2Pt(C5H5N2O2)2Pt(NH3)2](NO3)2.3H2O

Structure of Amorphous Platinum Uridine Green Sulfate by AWAXS and EXAFS

“…A crystalline Pt complex of type 2 has been synthesized with, e.g., 1-methylcytosine, but not with 1-methyluracil. Crystalline Pt−1-methyluracil complexes of types 3 and 4 with several Pt oxidation states are known. , The experimental Pt−Pt distance of 3 Å is in the range of typical intramolecular Pt−Pt distances of [Pt II ] 2 complexes. More oxidized dinuclear Pt complexes than 3 , like Pt II Pt III and [Pt III ] 2 , and tetranuclear Pt complexes than 4 , like [Pt II ] 2 [Pt III ] 2 , Pt II [Pt III ] 3 , and [Pt II ] 4 , are excluded, since their intramolecular Pt−Pt distances are expected to be shorter 8 than the experimental result, 3 Å.…”

“…The closest model Pt complexes for platinum uridine green sulfate are the mono-, di-, and tetranuclear Pt−1-methyluracil complexes, − which, however, lack the ribose part. The tetranuclear cis -diammineplatinum−1-methyluracil blue 28 was the first structurally characterized paramagnetic platinum pyrimidine blue.…”

Structural study of amorphous platinum 5-fluorouridine green sulfate

“…To interpret the experimental results for platinum 5fluorouridine green sulfate, model diplatinum() units, 2,4 and platinum() units 5,6 were constructed. The models 2,4 are both based on crystalline dinuclear cis-[Pt(NH 3 ) 2 (mura)] 2 [NO 3 ] 2 (mura = 1-methyluracil) complexes: head-to-head 1 48 and headto-tail 3, 49 where the ligand represents the closest analog available to 5-fluorouridine. The structure of an analog of 52 Since the crystal structure of 5-fluorouridine (fura) has not been determined, the conformation and the structure parameters of the ligand for the models 2, 4, 5 and 6 were taken from the crystal structure of 5-chlorouridine 53 by changing the C᎐Cl bond length for the C᎐F bond length.…”

An Improved Regularization Technique for Analysis of Anomalous X-ray Scattering Data; Platinum Uridine Blue Sulfate as an Example

“…To study this, the experimental RDF (17.4 keV) and Pt-Pt PDF were compared with those based on the structures of the crystalline dinuclear model Pt complexes (O'Halloran et al, 1987;Faggiani, Lock, Pollock, Rosenberg & Turner, 1981). The model RDF and PDF were obtained by calculation first of the total and the Pt-Pt partial structure factor from atomic coordinates and then of the model RDF and the Pt-Pt PDF with the same procedure that was used for obtaining the experimental ones.…”