Cryptococcal myelitis: A rare manifestation in immunocompetent patients

Cryptococcal infection causing longitudinal extensive transverse myelitis in an immunocompetent individual: Case report and literature review

“…He was put on consolidation therapy and is currently on maintenance therapy and has completely recovered on follow up. Others’ studies ( 4 , 8 , 9 ) also showed that correct diagnosis and prompt treatment results in 90% of patients showing complete recovery. This highlights the notion that if there are clinical pointers toward an infective etiology in case of a LETM, one should rule out cryptococcus CNS infection as it is a treatable condition ( 18 ).…”

“…Overall, in cases of cryptococcal myelitis the median duration of onset of symptoms prior to admission was 38 days (IQR 9.5, 90). In the three cases of LETM reported in literature the duration of symptoms was 5, 10, and 150 days, respectively, ( 4 , 8 , 9 ). In our case, the patient had a four-day history of weakness prior to admission.…”

“…Although other spinal cord manifestations of cryptococcus infections like epidural abscess, chronic arachnoiditis, both intra and extramedullary granuloma, myelitis and vasculitis have been described ( 6 , 7 ). A cryptococcal infection causing an acute LETM has been rarely described in literature ( 8 , 9 ).…”