1992
DOI: 10.1016/0003-4975(92)90632-e
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Cryopreserved allograft veins as alternative coronary artery bypass conduits: Early phase results

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Cited by 52 publications
(31 citation statements)
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“…Similarly, when satisfactory autologous SVGs are not available, cryopreserved homologous SVGs, either cryopreserved or denatured, can be an alternative conduit to the autologous ones in coronary artery bypass,127 construction of aortopulmonary communication,77 a modified Blalock-Taussig shunt,7879 and complex limb-salvage procedures 128129. Some authors127130131 have suggested that use of such conduits should be limited due to poor patency. Despite various types of stents that have been used to treat atherosclerotic stenoses of coronary, renal, and superficial femoral arteries, open surgery is still the treatment of choice when the angioplasty fails and the patient develops recurrent symptoms 15.…”
Section: Discussionmentioning
confidence: 99%
“…Similarly, when satisfactory autologous SVGs are not available, cryopreserved homologous SVGs, either cryopreserved or denatured, can be an alternative conduit to the autologous ones in coronary artery bypass,127 construction of aortopulmonary communication,77 a modified Blalock-Taussig shunt,7879 and complex limb-salvage procedures 128129. Some authors127130131 have suggested that use of such conduits should be limited due to poor patency. Despite various types of stents that have been used to treat atherosclerotic stenoses of coronary, renal, and superficial femoral arteries, open surgery is still the treatment of choice when the angioplasty fails and the patient develops recurrent symptoms 15.…”
Section: Discussionmentioning
confidence: 99%
“…Additionally it should be inexpensive and should promote good pulmonary artery growth, should not produce distortion and should be easy to take down. Encouraged by its use in coronary artery bypass grafting 11,13,14 and peripheral vessel revascularization 15,16 , homograft SVG has been used as a substitute for BTS with variable results [5][6][7][8] . Inspired by these reports we conducted this randomized controlled trial.…”
Section: Discussionmentioning
confidence: 99%
“…Eventually, infl ammatory cells will induce the release of growth factors and cytokines, stimulating the repair process and contributing to the proliferation, migration and matrix secretion of smooth muscle cells (SMCs), which leads to the development of intimal hyperplasia and stenosis of the lumen in the homograft (Fellstrom et al , 1999;Simon et al , 2000;Jurado et al , 2002). When used for CABG surgery, cryopreserved SVG homografts have shown unacceptably poor patency rates (Gelbfi sh et al , 1986;Sellke et al , 1991;Laub et al , 1992;Iaffaldano et al , 1995;Bilfi nger et al , 1997). This demonstrates that the complex cellular content of homografts creates an immune response that is above the threshold tolerated by the human body.…”
Section: Homograftsmentioning
confidence: 99%