Cross sectional study of the clinical characteristics of French primary care patients with COVID-19

Sebo, Paul; Tudrej, B.V.; Lourdaux, Julie; Cuzin, Clara; Floquet, Martin; Haller, Dagmar M.; Maisonneuve, Hubert

doi:10.1038/s41598-021-91685-3

Cited by 3 publications

(10 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Many also presented with nonspecific symptoms like headache, fatigue and myalgia. Some were rare like rash or frostbite [7][8][9]. Although it is crucial to have better understanding of signs and symptoms of covid 19 infection in primary care setting it is also found that valid correlation of symptoms with the diagnosis requires standard tools [10].…”

Section: Discussionmentioning

confidence: 99%

“…Although it is crucial to have better understanding of signs and symptoms of covid 19 infection in primary care setting it is also found that valid correlation of symptoms with the diagnosis requires standard tools [10]. Clinical Investigations, including inflammatory markers and radiological tests to rule out potential life-threatening complication like acute respiratory distress syndrome and multisystem inflammation were found to be essential in determining the severity index in the primary care settings like the approach in hospitals and other inpatient facilities [5][6][7]. The outcome of management and control was quite inspiring at the primary health care centers.…”

Section: Discussionmentioning

confidence: 99%

“…In the early phase of pandemic there was constantly evolving and changing symptomatology). [6][7][8] Cough, sore throat, fever, diarrhea, shortness of breath were predominant complaints in patients attending fever clinics in Primary Health Center in Dubai involved in screening of suspected Covid 19 patients. Almost half of the patients had a cough and sore throat.…”

Section: Discussionmentioning

confidence: 99%

“…In the early part of pandemic, without proper tools and protocols to triage suspected covid 19 patients. High variability was noted in evaluation of suspected covid 19 patients [7][8][9]. Similar concerns were raised in 2009, during the H1N1 pandemic and the need for proper tools and protocols to triage patients with HIN1 flu was highlighted [9].…”

Section: Annals Of Reviews and Researchmentioning

confidence: 99%

“…This warrants the need for standardized tools for screening, rapid identification, triaging, and implementing infection control practices specific for PHC [5,6]. Dubai health authority published its first pathway for management of suspected covid 19 cases in April 2020 to guide primary care clinicians on how to approach suspected covid 19 cases [7].…”

Section: Annals Of Reviews and Researchmentioning

confidence: 99%

See 4 more Smart Citations

"Management of suspected COVID-19 Infection in Primary Health Care Center"

Sharma

2023

ARR

View full text Add to dashboard Cite

Introduction: Primary health care centers have played a very significant role as gatekeepers in early detection and clinical management of COVID19cases during the pandemic. These dedicated centers stepped up the response measures to find, isolate, test, treat and trace transmission to save lives. The COVID clinics were set up to ensure that the health care providers follow a set of protocols in effective triaging of patients based on clinical presentation and comorbid conditions. This study aims to analyze and report the initial experience with the epidemiologic investigation, clinical features, and referrals of suspected COVID 19 cases in UAE. Methods:This cross-sectional study includes 1000 suspected Covid 19 cases who attended the CoVID 19 clinics in the primary health care centers of, Dubai Health Authority, over a period of 3 months from March 2020 to June 2020. Clinical, laboratory and radiologic data relevant to these cases were extracted from the electronic patient records of Dubai health authority (DHA) for analysis and interpretation.Results: There was no pattern of correlation between sign and symptoms, risk factors, ordering investigations or referring the patient for hospitalization in primary health care centers in Dubai at the beginning of pandemic. The Durbin Watson Regression analysis score of 1.6 and 1.468 and p value of < 1. The result indicates that there is a weak relationship between the independent variables (signs and symptoms checked/ observed) and dependent variable (testing for Covid 19 diagnosis). In terms of investigations, it was also found that there is a weak relationship between the independent variables (investigations) and the dependent variable (Covid 19 diagnosis).Discussion/Conclusion: Fever clinics and screening centers were established in primary care centers as a response to the Covid 19 pandemic wherein the infections in the community could be screened and identified. It was critical to identify the patients on basis of symptomatology, predefined risk factors like travel and contact with covid19 cases and to check vital signs, order relevant investigation to establish diagnosis severity levels for referrals to hospitals for admission. Potential concerns were raised about the use of existing triaging methods for suspected Covid 19 infections in the early part of epidemic from March 2020 to June 2020. The variability and poor correlation noted in screening and management of people suspected of having Covid 19 infection in early part of pandemic highlights the need for further research to evaluate existing triaging methods available in primary health centers. There is a need to establish standard triaging techniques in primary health centers like the hospitals in such global outbreaks.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Annals Of Reviews and Researchmentioning

confidence: 99%

Section: Annals Of Reviews and Researchmentioning

confidence: 99%

See 3 more Smart Citations

"Management of suspected COVID-19 Infection in Primary Health Care Center"

Sharma

2023

ARR

View full text Add to dashboard Cite

show abstract

COVID-19 assessment in family practice—A clinical decision rule based on self-rated symptoms and contact history

Schneider

Rauscher

Kellerer

et al. 2021

npj Prim. Care Respir. Med.

View full text Add to dashboard Cite

The study aimed to evaluate the diagnostic accuracy of contact history and clinical symptoms and to develop decision rules for ruling-in and ruling-out SARS-CoV-2 infection in family practice. We performed a prospective diagnostic study. Consecutive inclusion of patients coming for COVID-PCR testing to 19 general practices. Contact history and self-reported symptoms served as index test. PCR testing of nasopharyngeal swabs served as reference standard. Complete data were available from 1141 patients, 605 (53.0%) female, average age 42.2 years, 182 (16.0%) COVID-PCR positive. Multivariable logistic regression showed highest odds ratios (ORs) for “contact with infected person” (OR 9.22, 95% CI 5.61–15.41), anosmia/ageusia (8.79, 4.89–15.95), fever (4.25, 2.56–7.09), and “sudden disease onset” (2.52, 1.55–4.14). Patients with “contact with infected person” or “anosmia/ageusia” with or without self-reported “fever” had a high probability of COVID infection up to 84.8%. Negative response to the four items “contact with infected person, anosmia/ageusia, fever, sudden disease onset” showed a negative predictive value (NPV) of 0.98 (95% CI 0.96–0.99). This was present in 446 (39.1%) patients. NPV of “completely asymptomatic,” “no contact,” “no risk area” was 1.0 (0.96–1.0). This was present in 84 (7.4%) patients. To conclude, the combination of four key items allowed exclusion of SARS-CoV-2 infection with high certainty. With the goal of 100% exclusion of SARS-CoV-2 infection to prevent the spread of SARS-CoV-2 to the population level, COVID-PCR testing could be saved only for patients with negative response in all items. The decision rule might also help for ruling-in SARS-CoV-2 infection in terms of rapid assessment of infection risk.

show abstract

Predictors of Positive Real-Time Reverse Transcription–Polymerase Chain Reaction Result for Severe Acute Respiratory Syndrome Coronavirus 2

Ioakeimidis¹,

Arvanitakis²,

Vakfari³

et al. 2022

Infect Dis Clin Pract

View full text Add to dashboard Cite

Background The COVID-19 pandemic imposed a great burden on every healthcare sector including primary care. Confident clinical decisions, proactive isolation of suspicious cases, and testing resource allocation are of crucial importance at primary care facilities. The criterion standard for the diagnosis of COVID-19, a multisystem disease with diverse symptoms, is real-time reverse-transcription polymerase chain reaction (rRT-PCR). Objectives We aim to identify clinical and demographic predictors of a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rRT-PCR test result at a single primary care facility in Greece. Methods A single-center retrospective cross-sectional study was carried out from October 22 to November 23, 2020, investigating various characteristics of individuals presenting at a primary care facility for rRT-PCR testing for the detection of SARS-CoV-2. Logistic regression was performed to identify clinical and demographic predictors of a positive rRT-PCR test result for the detection of SARS-CoV-2. Results A total of 118 specimens were included in the study, corresponding to 118 individuals, whose median age was 43.5 years (interquartile range, 28 years). Most of the participants were symptomatic (69.5%; n = 82), with fever (40.7%; n = 48), cough (21.2%; n = 25), and nasal congestion/discharge (16.9%; n = 20) being the most common presenting symptoms. The probability of a positive SARS-CoV-2 rRT-PCR result was greater for patients presenting with fever (odds ratio [OR], 10.631; 95% confidence interval [CI], 2.402–47.055; P = 0.002), anosmia or ageusia (OR, 9.56; 95% CI, 1.481–61.704; P = 0.018), and nasal congestion or discharge (OR, 7.138; 95% CI, 1.329–38.353; P = 0.022), compared with patients without. Conclusions The presence of fever, anosmia or ageusia, and nasal congestion or discharge may successfully predict a positive SARS-Cov-2 rRT-PCR test result at primary care settings.

show abstract

Cross sectional study of the clinical characteristics of French primary care patients with COVID-19

Cited by 3 publications

References 30 publications

"Management of suspected COVID-19 Infection in Primary Health Care Center"

"Management of suspected COVID-19 Infection in Primary Health Care Center"

COVID-19 assessment in family practice—A clinical decision rule based on self-rated symptoms and contact history

Predictors of Positive Real-Time Reverse Transcription–Polymerase Chain Reaction Result for Severe Acute Respiratory Syndrome Coronavirus 2

Contact Info

Product

Resources

About