Cross‐sectional diagnostic accuracy study of self‐testing for proteinuria during hypertensive pregnancies: The <scp>UDIP</scp> study

Jakubowski, Beth; Stevens, R J; Wilson, Hannah; Lavallee, Layla; Brittain, Lesley; Crawford, Carole; Hodgkinson, James; Hinton, Lisa; Mackillop, Lucy; Chappell, Lucy C; McManus, Richard J; Tucker, Katherine L.

doi:10.1111/1471-0528.17180

Cited by 5 publications

(6 citation statements)

References 23 publications

(63 reference statements)

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“…Home blood pressure monitoring both during pregnancy and postpartum has been demonstrated previously to be feasible and acceptable to pregnant and postpartum individuals 35–37 . Recent data also support the use of home monitoring for proteinuria during pregnancy, which may be particularly useful when incorporated into remote approaches to antenatal care 38 …”

Section: Discussionmentioning

confidence: 89%

“…[35][36][37] Recent data also support the use of home monitoring for proteinuria during pregnancy, which may be particularly useful when incorporated into remote approaches to antenatal care. 38 Despite promising data in the non-pregnant population, few studies have investigated self-monitoring of BP combined with additional support. Our study suggests a modest lowering of blood pressure in the intervention arms.…”

Section: Mean (95% Ci) or Median [Iqr]mentioning

confidence: 99%

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Postpartum home blood pressure monitoring and lifestyle intervention in overweight and obese individuals the first year after gestational hypertension or pre‐eclampsia: A pilot feasibility trial

Hauspurg

Seely

Rich‐Edwards

et al. 2023

BJOG

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Objective To test the feasibility of a randomised trial of home blood pressure monitoring paired with a remote lifestyle intervention (Heart Health 4 New Moms) versus home blood pressure monitoring alone versus control in individuals with a hypertensive disorder of pregnancy in the first year postpartum. Design Single‐blinded three‐arm randomised clinical trial. Setting Two tertiary care hospitals and a community organisation. Population Postpartum overweight and obese individuals with a hypertensive disorder of pregnancy and without pre‐pregnancy hypertension or diabetes. Methods We assessed the feasibility of recruitment and retention of 150 participants to study completion at 1‐year postpartum with randomisation 1:1:1 into each arm. Secondary aims were to test effects of the interventions on weight, blood pressure and self‐efficacy. Results Over 23 months, we enrolled 148 of 400 eligible, screened individuals (37%); 28% black or other race and mean pre‐pregnancy body mass index (BMI) of 33.4 ± 6.7 kg/m2. In total, 129 (87%) participants completed the 1‐year postpartum study visit. Overall, 22% of participants developed stage 2 hypertension (≥140/90 mmHg or on anti‐hypertensive medications) by 1 year postpartum. There were no differences in weight or self‐efficacy across the study arms. Conclusion In this pilot, randomised trial, we demonstrate feasibility of HBPM paired with a lifestyle intervention in the first year postpartum. We detected high rates of ongoing hypertension, emphasising the need for the development of effective interventions in this population.

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Section: Discussionmentioning

confidence: 89%

Section: Mean (95% Ci) or Median [Iqr]mentioning

confidence: 99%

Postpartum home blood pressure monitoring and lifestyle intervention in overweight and obese individuals the first year after gestational hypertension or pre‐eclampsia: A pilot feasibility trial

Hauspurg

Seely

Rich‐Edwards

et al. 2023

BJOG

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“…At present, test strips are used for a quick and simple diagnosis of proteinuria, easy to handle and apply both by primary health personnel in a prenatal consultation, and for use by the patient at home [30]. Although they can give results as false positives or negatives, motivated by the fact that the presence of pathologies prior to pregnancy or not must be known, it is useful in patients with blood pressures of 140/90 mmHg, for monitoring at home, which allows go to a care center if they are positive [30].…”

Section: Usefulness Of Urinementioning

confidence: 99%

Usefulness of Urine Tests in the Prevention, Diagnosis, Treatment and Prognosis of Pathologies Present during Pregnancy

Villalobos

2024

Advances and Challenges in Urine Laboratory Analysis

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Pregnancy produces physiological changes in the woman necessary to be able to bring it to a happy term. However, they can favor the development of pathologies in various organs and systems, ranging from urinary infections, diabetes mellitus or gestational to hypertensive disorders of pregnancy. Which produce substances that are excreted through the urine. There is also excretion of metabolites which can be evaluated for the diagnosis and prognosis of certain chromosomopathies. These substances, when measured or quantified, provide bases for diagnosis, prevention, and allow decisions to be made regarding timely treatment in many of them.

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“…Early work from small observational studies suggested the potential for reduced morbidity and resource use, as well as acceptability and feasibility, yet evidence from large-scale randomised trials for the effectiveness of SMBP in pregnancy has been lacking until recently [ 7 – 9 ]. This article reviews the findings from the Blood Pressure Monitoring in Pregnancy (BUMP) programme of work, undertaken in the United Kingdom (UK), in this rapidly developing area [ 10 – 13 ].…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore, the study also showed that automated colorimetric testing was not significantly different to performance by women or healthcare professionals. Although the accuracy of urine dipstick testing is not as high as desired in a diagnostic test, testing in the context of antenatal care, which includes repeated testing, is likely to be beneficial [ 13 ]. Furthermore, using protein testing in combination with home BP monitoring could allow better reassurance to both healthcare professionals and women that the important indicators of evolving pre-eclampsia are being monitored.…”

Section: Introductionmentioning

confidence: 99%

Using self-monitoring to detect and manage raised blood pressure and pre-eclampsia during pregnancy: the BUMP research programme and its impact

Tucker,

Hinton,

Green

et al. 2023

Hypertens Res

Self Cite

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Raised blood pressure affects around ten percent of pregnancies worldwide, causing maternal and perinatal morbidity and mortality. Self-monitoring of blood pressure during higher-risk or hypertensive pregnancy has been shown to be feasible, acceptable, safe, and no more expensive than usual care alone. Additionally, self-testing for proteinuria has been shown to be just as accurate as healthcare professional testing, creating the potential for monitoring of multiple indicators through pregnancy. The work suggests however, that an organisational shift is needed to properly use and see benefits from self-monitored readings. This paper describes the findings from a large programme of work examining the use of self-monitoring in pregnancy, summarising the findings in the context of the wider literature and current clinical context.

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Cross‐sectional diagnostic accuracy study of self‐testing for proteinuria during hypertensive pregnancies: The UDIP study

Abstract: Objective: To determine the accuracy of self-testing for proteinuria during pregnancy.

Cited by 5 publications

References 23 publications

Postpartum home blood pressure monitoring and lifestyle intervention in overweight and obese individuals the first year after gestational hypertension or pre‐eclampsia: A pilot feasibility trial

Postpartum home blood pressure monitoring and lifestyle intervention in overweight and obese individuals the first year after gestational hypertension or pre‐eclampsia: A pilot feasibility trial

Usefulness of Urine Tests in the Prevention, Diagnosis, Treatment and Prognosis of Pathologies Present during Pregnancy

Using self-monitoring to detect and manage raised blood pressure and pre-eclampsia during pregnancy: the BUMP research programme and its impact

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